Title:
ENZYME INHIBITORS OF PAI-1
Document Type and Number:
WIPO Patent Application WO2007047205
Kind Code:
A8
Abstract:
The invention provides a method for the treatment of a subject suffering from a cardiovascular disease using a therapeutically effective amount of at least one enzyme that is capable of inhibiting PAI-I activity. The invention also provides a method of decreasing the risk of the occurrence of a cardiovascular disease in a subject who presents at least one risk factor that is associated with a cardiovascular disease, by administering to the subject a therapeutically effective amount of at least one enzyme that is capable of inhibiting PAI-I activity. Additionally, the invention provides a method of inhibiting PAI-I activity in a subject in need thereof, where the subject is administered an enzyme selected from a protease or peptidase.
Inventors:
JOLLY JAMES F (US)
Application Number:
PCT/US2006/039415
Publication Date:
August 23, 2007
Filing Date:
October 10, 2006
Export Citation:
Assignee:
AMANO ENZYME USA CO LTD (US)
AMANO ENZYME INC (JP)
JOLLY JAMES F (US)
AMANO ENZYME INC (JP)
JOLLY JAMES F (US)
International Classes:
A61K38/48; A61P9/10
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