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Title:
ERYTHROPOIETIN PRODUCTION-PROMOTING AGENT
Document Type and Number:
WIPO Patent Application WO/2013/054755
Kind Code:
A1
Abstract:
[Problem] To provide a treatment agent and/or a prophylactic agent for renal anemia. Also, to provide an erythropoietin production-promoting agent. [Solution] This invention provides a treatment agent and/or a prophylactic agent for renal anemia containing ALA substances. Further, this invention provides an erythropoietin production-promoting agent containing ALA substances.

Inventors:
TANAKA TOHRU (JP)
NAKAJIMA MOTOWO (JP)
TAKAHASHI KIWAMU (JP)
ABE TAKAAKI (JP)
Application Number:
PCT/JP2012/075947
Publication Date:
April 18, 2013
Filing Date:
October 05, 2012
Export Citation:
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Assignee:
SBI PHARMACEUTICALS CO LTD (JP)
International Classes:
A61K31/28; A61K31/197; A61K33/06; A61K33/26; A61K33/30; A61P7/06; A61P13/12; A61P43/00
Foreign References:
JP2003040770A2003-02-13
JP2006069963A2006-03-16
JP2008536935A2008-09-11
JP2009504766A2009-02-05
JP2006008720A2006-01-12
JP4754731B22011-08-24
Other References:
NEUMCKE,I. ET AL.: "Effects of pro- and antioxidative compounds on renal production of erythropoietin", ENDOCRINOLOGY, vol. 140, no. 2, 1999, pages 641 - 645, XP055148983
IENAGA,K. ET AL.: "First indications demonstrating the preventive effects of NZ-419, a novel intrinsic antioxidant, on the initiation and/or progression of chronic renal failure in rats", BIOL. PHARM. BULL., vol. 32, no. 7, 2009, pages 1204 - 1208, XP055148987
JENSEN,J.D. ET AL.: "Reduced production, absorption, and elimination of erythropoietin in uremia compared with healthy volunteers", J. AM. SOC. NEPHROL., vol. 5, no. 2, 1994, pages 177 - 185, XP055148995
See also references of EP 2767279A4
Attorney, Agent or Firm:
NANJO, Masahiro et al. (JP)
Masahiro Nanjo (JP)
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Claims: