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Title:
ESTER COMPOUND
Document Type and Number:
WIPO Patent Application WO/2020/153431
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a compound that is useful as an active ingredient for preventing and treating inflammatory diseases and that has a chemical structure to function as a specific antedrug having an effect of activating SIRT6. The present invention pertains to a compound represented by formula (1), or a pharmaceutically acceptable salt thereof (each symbol in formula (1) is identical to that defined in the description).

Inventors:
KAWAI JUNYA (JP)
NAKAJIMA KATSUYOSHI (JP)
IWAMOTO OSAMU (JP)
TSURUOKA HIROYUKI (JP)
SAITO KEIJI (JP)
KURIKAWA NOBUYA (JP)
NISHIHAMA NATSUMI (JP)
TANAKA SHINJI (JP)
OGITANI MOMOKO (JP)
HIRASAWA MAKOTO (JP)
SAITOH WATARU (JP)
MAKABE MUNEYOSHI (JP)
Application Number:
PCT/JP2020/002349
Publication Date:
July 30, 2020
Filing Date:
January 23, 2020
Export Citation:
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Assignee:
DAIICHI SANKYO CO LTD (JP)
International Classes:
A61P1/00; A61K31/437; A61K31/4995; A61K31/5386; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P9/04; A61P9/10; A61P11/00; A61P11/02; A61P11/04; A61P11/06; A61P11/08; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P17/08; A61P17/14; A61P19/02; A61P25/00; A61P25/02; A61P27/02; A61P27/14; A61P27/16; A61P29/00; A61P37/02; A61P37/08; A61P43/00; C07D513/04; C07D513/18
Domestic Patent References:
WO2010125799A12010-11-04
WO2010024258A12010-03-04
WO2014113191A12014-07-24
Foreign References:
US4289524A1981-09-15
JP2015097508A2015-05-28
JP2015038046A2015-02-26
Other References:
YOU, W. ET AL.: "Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 56, no. 4, 2017, pages 1007 - 1011, XP055726962
Attorney, Agent or Firm:
EIKOH PATENT FIRM, P.C. (JP)
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