Title:
ESTER COMPOUNDS AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/246925
Kind Code:
A1
Abstract:
Disclosed in the present invention are compounds or pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers or isotope labeled compounds thereof. The compounds are as shown in formula (I). Also disclosed in the present invention is the use of the compounds in preparation of a drug for preventing or treating diseases related to aging.
Inventors:
JI YIN (CN)
WANG XUEPING (CN)
ZHAI HUI (CN)
WANG XUEPING (CN)
ZHAI HUI (CN)
Application Number:
PCT/CN2023/101960
Publication Date:
December 28, 2023
Filing Date:
June 21, 2023
Export Citation:
Assignee:
NANJING REJU THERAPEUTICS INC (CN)
International Classes:
C07D417/14; A61K31/4725; A61P35/00; C07D471/04; C07D487/04; C07D513/04
Domestic Patent References:
| WO2023044046A1 | 2023-03-23 |
Foreign References:
| CN103987711A | 2014-08-13 | |||
| CN107249643A | 2017-10-13 | |||
| CN109600993A | 2019-04-09 |
Other References:
WANG LE, DOHERTY GEORGE A., JUDD ANDREW S., TAO ZHI-FU, HANSEN T. MATTHEW, FREY ROBIN R., SONG XIAOHONG, BRUNCKO MILAN, KUNZER AAR: "Discovery of A-1331852, a First-in-Class, Potent, and Orally-Bioavailable BCL-X L Inhibitor", ACS MEDICINAL CHEMISTRY LETTERS, AMERICAN CHEMICAL SOCIETY, US, vol. 11, no. 10, 8 October 2020 (2020-10-08), US , pages 1829 - 1836, XP093120763, ISSN: 1948-5875, DOI: 10.1021/acsmedchemlett.9b00568
Attorney, Agent or Firm:
IPSUNNY (CN)
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