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Title:
ESTROGEN RECEPTOR ANTAGONIST
Document Type and Number:
WIPO Patent Application WO/2020/125640
Kind Code:
A1
Abstract:
Provided is an indole compound. In particular, disclosed are a compound represented by formula (II) or an isomer or pharmaceutically acceptable salt thereof and a use of the same as an estrogen receptor antagonist in preparing a drug for treating estrogen receptor-positive breast cancer.

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Inventors:
DUAN SHUWEN (CN)
LU JIANYU (CN)
HU LIHONG (CN)
DING CHARLES Z (CN)
HU GUOPING (CN)
LI JIAN (CN)
CHEN SHUHUI (CN)
Application Number:
PCT/CN2019/126046
Publication Date:
June 25, 2020
Filing Date:
December 17, 2019
Export Citation:
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Assignee:
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN)
MEDSHINE DISCOVERY INC (CN)
International Classes:
C07D209/08; A61P35/00; C07D221/02
Domestic Patent References:
WO2018098251A12018-05-31
WO2016196342A12016-12-08
Foreign References:
CN107847498A2018-03-27
CN103189361A2013-07-03
CN104220426A2014-12-17
US20160347717A12016-12-01
Other References:
See also references of EP 3889133A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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