Title:
ETHER BENZYLIDENE PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2009/127944
Kind Code:
A8
Abstract:
The present invention relates to compounds of Formula (I) wherein Ar is optionally substituted phenyl or 6-membered heteroaryl moiety, or a benzisoxazole, pyrrolopyridine, or benzotriazole group; or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity, including pain, urinary incontinence, overactive bladder, emesis, cognitive disorders, anxiety, depression, sleeping disorders, eating disorders, movement disorders, glaucoma, psoriasis, multiple sclerosis, cerebrovascular disorders, brain injury, gastrointestinal disorders, hypertension, or cardiovascular disease.
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Inventors:
FAY LORRAINE KATHLEEN (GB)
JOHNSON DOUGLAS SCOTT (US)
MEYERS MARVIN JAY (US)
THORARENSEN ATLI (US)
WANG LIJUAN JANE (US)
JOHNSON DOUGLAS SCOTT (US)
MEYERS MARVIN JAY (US)
THORARENSEN ATLI (US)
WANG LIJUAN JANE (US)
Application Number:
PCT/IB2009/005246
Publication Date:
December 09, 2010
Filing Date:
April 09, 2009
Export Citation:
Assignee:
PFIZER (US)
FAY LORRAINE KATHLEEN (GB)
JOHNSON DOUGLAS SCOTT (US)
MEYERS MARVIN JAY (US)
THORARENSEN ATLI (US)
WANG LIJUAN JANE (US)
FAY LORRAINE KATHLEEN (GB)
JOHNSON DOUGLAS SCOTT (US)
MEYERS MARVIN JAY (US)
THORARENSEN ATLI (US)
WANG LIJUAN JANE (US)
International Classes:
C07D211/70; A61K31/4427; A61P9/00; A61P25/00; A61P29/00; C07D401/12; C07D413/12
Attorney, Agent or Firm:
RICHARDSON, Peter, C. (150 East 42nd StreetNew York, New York, US)
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