Title:
ETHYL CARBAMATE HAPTEN COMBINATION, ARTIFICIAL ANTIGEN COMBINATION, AND METHOD FOR PREPARING SAME AND APPLICATION OF SAME
Document Type and Number:
WIPO Patent Application WO/2018/032359
Kind Code:
A1
Abstract:
Provided are an ethyl carbamate hapten combination, artificial antigen combination, and method for preparing same and application of same. The ethyl carbamate artificial antigen combination has the molecular structure as shown in formula (III) and formula (IV); the potency of the antiserum obtained by said artificial antigen may reach 1.28×105, the minimum limit of detection is 0.16 mg/L, and the semi-inhibitory concentration is 1.19 mg/L; the specificity of the prepared antibody is high, sensitivity is high, and accuracy is high; it is possible to establish an immunoassay method for detecting ethyl carbamate; high-throughput screening for ethyl carbamate in food products is achieved, detection efficiency is improved, and detection costs are reduced.
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Inventors:
XU ZHENLIN (CN)
SUN YUANMING (CN)
LUO LIN (CN)
YANG JINYI (CN)
LEI HONGTAO (CN)
SHEN YUDONG (CN)
WANG HONG (CN)
SUN YUANMING (CN)
LUO LIN (CN)
YANG JINYI (CN)
LEI HONGTAO (CN)
SHEN YUDONG (CN)
WANG HONG (CN)
Application Number:
PCT/CN2016/095543
Publication Date:
February 22, 2018
Filing Date:
August 16, 2016
Export Citation:
Assignee:
UNIV SOUTH CHINA AGRICULT (CN)
International Classes:
C07C269/04; C07C271/22; C07C271/28; C07K14/77; C07K14/795; C07K16/44; G01N33/531; G01N33/543; G01N33/577
Foreign References:
| CN102718861A | 2012-10-10 | |||
| CN101463086A | 2009-06-24 | |||
| CN101407501A | 2009-04-15 | |||
| CN106366021A | 2017-02-01 | |||
| CN101987836A | 2011-03-23 | |||
| CN103197061A | 2013-07-10 | |||
| CN101412697A | 2009-04-22 |
Attorney, Agent or Firm:
YOGO PATENT & TRADE MARK AGENCY LIMITED COMPANY (CN)
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