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Title:
EVALUATION METHOD FOR VASCULAR HYPERPERMEABILITY REGULATION ACTION
Document Type and Number:
WIPO Patent Application WO/2014/129653
Kind Code:
A1
Abstract:
A method that uses the peak height of endothelium cells in a test substance as an indicator of vascular hyperpermeability regulation action in the endothelium cells, and which comprises: a step in which the test substance is brought in contact with the endothelium cells; a step in which a drug that exacerbates vascular permeability in endothelium cells is brought in contact with the endothelium cells; and a step in which the peak height of the endothelium cells is measured.

Inventors:
YAMAUCHI Toyohiko (1126-1 Ichino-cho, Higashi-ku, Hamamatsu-sh, Shizuoka 58, 〒4358558, JP)
HIRAKAWA Satoshi (20-1 Handayama 1-chome, Higashi-ku, Hamamatsu-sh, Shizuoka 92, 〒4313192, JP)
YAMASHITA Yutaka (1126-1 Ichino-cho, Higashi-ku, Hamamatsu-sh, Shizuoka 58, 〒4358558, JP)
TOKURA Yoshiki (20-1 Handayama 1-chome, Higashi-ku, Hamamatsu-sh, Shizuoka 92, 〒4313192, JP)
Application Number:
JP2014/054528
Publication Date:
August 28, 2014
Filing Date:
February 25, 2014
Export Citation:
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Assignee:
HAMAMATSU PHOTONICS K.K. (1126-1, Ichino-cho Higashi-ku, Hamamatsu-sh, Shizuoka 58, 〒4358558, JP)
International Classes:
C12Q1/02
Foreign References:
JP2005002093A2005-01-06
JP2006506321A2006-02-23
JP2012524058A2012-10-11
JP2012530784A2012-12-06
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (SOEI PATENT AND LAW FIRM, Marunouchi MY PLAZA 9th fl. 1-1, Marunouchi 2-chome, Chiyoda-k, Tokyo 05, 〒1000005, JP)
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