Title:
EXATECAN DERIVATIVES, LINKER-PAYLOADS, AND CONJUGATES AND THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/088235
Kind Code:
A1
Abstract:
The present disclosure relates to the biopharmaceutical field, in particular, Exatecan derivatives, linker-payloads, and conjugates and thereof antibody-drug conjugates, and the corresponding preparing process and use thereof.
Inventors:
QIN GANG (CN)
ZHANG TONY YANTAO (CN)
CHEN GUANGMING (CN)
SONG PAUL H (CN)
ZHONG BOYU (CN)
HU MINGYU (CN)
ZHANG TONY YANTAO (CN)
CHEN GUANGMING (CN)
SONG PAUL H (CN)
ZHONG BOYU (CN)
HU MINGYU (CN)
Application Number:
PCT/CN2022/131904
Publication Date:
May 25, 2023
Filing Date:
November 15, 2022
Export Citation:
Assignee:
GENEQUANTUM HEALTHCARE SUZHOU CO LTD (CN)
International Classes:
C07K7/06; A61K31/165; A61K31/475; A61K31/537; A61K38/07; A61K45/00; A61K47/65; A61K47/68; A61P35/00; A61P37/02; C07D491/22; C07K5/103
Domestic Patent References:
| WO2020063673A1 | 2020-04-02 | |||
| WO2021052402A1 | 2021-03-25 | |||
| WO2021115426A1 | 2021-06-17 | |||
| WO2021190586A1 | 2021-09-30 | |||
| WO2022166762A1 | 2022-08-11 | |||
| WO2022218331A1 | 2022-10-20 | |||
| WO2022068878A1 | 2022-04-07 | |||
| WO2015165413A1 | 2015-11-05 | |||
| WO2014057687A1 | 2014-04-17 | |||
| WO2015165413A1 | 2015-11-05 |
Foreign References:
| CN104755494A | 2015-07-01 | |||
| CN111689980A | 2020-09-22 | |||
| CN115103691A | 2022-09-23 | |||
| CN110167355A | 2019-08-23 | |||
| EP2907824A1 | 2015-08-19 | |||
| US20110321183A1 | 2011-12-29 |
Other References:
See also references of EP 4211145A4
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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