Title:
EXTENDED RELEASE ORAL DOSAGE COMPOSITION
Document Type and Number:
WIPO Patent Application WO2001045676
Kind Code:
A3
Abstract:
A compressed bilayer solid composition comprising (a) an immediate release first layer comprising an anti-allergic effective amount of desloratadine and at least one pharmaceutically acceptable excipient and (b) a sustained release second layer comprising an effective amount of a nasal decongestant and a pharmaceutically acceptable sustained release agent wherein the composition contains less than about 2 % of desloratadine decomposition products is disclosed.
Inventors:
CHO WING-KEE PHILIP (US)
Application Number:
PCT/US2000/034404
Publication Date:
January 03, 2002
Filing Date:
December 19, 2000
Export Citation:
Assignee:
SCHERING CORP (US)
CHO WING KEE PHILIP (US)
CHO WING KEE PHILIP (US)
International Classes:
A61K9/20; A61K9/24; A61K31/137; A61K31/445; A61K31/4545; A61K31/473; A61K45/00; A61K47/04; A61K47/12; A61K47/18; A61K47/32; A61K47/36; A61K47/38; A61P11/02; A61P37/08; A61K47/02; (IPC1-7): A61K9/24; A61K31/4545
Domestic Patent References:
WO1999062516A1 | 1999-12-09 | |||
WO2000002560A1 | 2000-01-20 | |||
WO1998034614A1 | 1998-08-13 |
Foreign References:
EP0396404A1 | 1990-11-07 | |||
EP0577957A1 | 1994-01-12 | |||
EP0264259A1 | 1988-04-20 |
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