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Title:
Fab REGION-BINDING PEPTIDE
Document Type and Number:
WIPO Patent Application WO/2015/030094
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide: a Fab region-binding peptide having an excellent capacity for binding to a Fab region of IgG; an affinity separation matrix having the peptide as a ligand; and a method for producing a Fab region-containing protein, said method using the affinity separation matrix. A further purpose of the present invention is to provide: DNA which codes for the peptide; a vector which contains the DNA; and a transformant which has been transformed by the vector. This Fab region-binding peptide is characterised by having a mutation at a specific site, in contrast to wild-type SpG-β1.

Inventors:
YOSHIDA SHINICHI (JP)
MURATA DAI (JP)
Application Number:
PCT/JP2014/072524
Publication Date:
March 05, 2015
Filing Date:
August 28, 2014
Export Citation:
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Assignee:
KANEKA CORP (JP)
International Classes:
C07K14/315; C07K1/22; C07K17/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/09
Domestic Patent References:
WO1998001560A11998-01-15
WO2013041730A12013-03-28
WO2013018880A12013-02-07
WO1997026930A11997-07-31
Foreign References:
JP2009195184A2009-09-03
JP2011232098A2011-11-17
JP2008115151A2008-05-22
JPS63503032A1988-11-10
JP2009195184A2009-09-03
Other References:
HOBER S. ET AL., J.CHROMATOGR, B, vol. 848, 2007, pages 40 - 47
SHUKLA A.A. ET AL., TRENDS BIOTECHNOL., vol. 28, 2010, pages 253 - 261
NELSON A.N. ET AL., NAT.BIOTECHNOL., vol. 27, 2009, pages 331 - 337
BOUVET P.J., INT. J. IMMUNOPHARMAC., vol. 16, 1994, pages 419 - 424
DERRICK J.P., NATURE, vol. 359, 1992, pages 752 - 754
AKERSTROM ET AL., J. BIOL. CHEM., vol. 28, 1987, pages 13388
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ALEXANDER ET AL., BIOCHEMISTRY, vol. 31, 1992, pages 3597
NAGATA ET AL.: "Real-time analysis experiment of biomaterial interactions", 1998, SPRINGER-VERLAG TOKYO, pages: 41
See also references of EP 3040344A4
Attorney, Agent or Firm:
UEKI, Kyuichi et al. (JP)
Hisakazu Ueki (JP)
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