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Title:
FATTY ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/143946
Kind Code:
A1
Abstract:
Provided are a fatty acid compound, a preparation method therefor and use thereof. The fatty acid compound is of a structure represented by general formula I. The compound has an AMPK activating activity and a capability of inhibiting glucose production in mouse primary hepatocytes, and can be used for preparing drugs for treating obesity or diabetes.

Inventors:
NAN, Fajun (555 Zu Chong Zhi Road, Zhang Jiang Pudong, Shanghai 3, 201203, CN)
LI, Jia (555 Zu Chong Zhi Road, Zhang Jiang Pudong, Shanghai 3, 201203, CN)
LI, Jingya (555 Zu Chong Zhi Road, Zhang Jiang Pudong, Shanghai 3, 201203, CN)
ZHANG, Mei (555 Zu Chong Zhi Road, Zhang Jiang Pudong, Shanghai 3, 201203, CN)
XIE, Zhifu (555 Zu Chong Zhi Road, Zhang Jiang Pudong, Shanghai 3, 201203, CN)
WANG, Jingtao (555 Zu Chong Zhi Road, Zhang Jiang Pudong, Shanghai 3, 201203, CN)
GUO, Dongdong (555 Zu Chong Zhi Road, Zhang Jiang Pudong, Shanghai, CN)
Application Number:
CN2017/074039
Publication Date:
August 31, 2017
Filing Date:
February 20, 2017
Export Citation:
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Assignee:
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (555 Zu Chong Zhi Road, Zhang Jiang Pudong, Shanghai 3, 201203, CN)
International Classes:
C07C57/13; A61K31/194; A61P3/04; A61P3/10; C07C51/09; C07C55/28; C07C57/42; C07C61/35
Domestic Patent References:
WO1996011901A11996-04-25
Foreign References:
US4711896A1987-12-08
US4689344A1987-08-25
Other References:
DATABASE CAS 5 June 2009 (2009-06-05), retrieved from STN Database accession no. RN 71042-01-8
See also references of EP 3421447A4
Attorney, Agent or Firm:
KINGSOUND & PARTNERS (11/F, Block B KingSound International Center, 116 Zizhuyuan Road, Haidian District, Beijing 7, 100097, CN)
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