Title:
FATTY ACID MODIFIED FORMS OF GLUCOCORTICOIDS AND THEIR USE AS ANTI-INFLAMMATORY
Document Type and Number:
WIPO Patent Application WO2004033478
Kind Code:
A3
Abstract:
A genus of 11,21-dihydroxypregna-1,4-diene-3,20-diones is disclosed, in which the 21-hydroxy is esterified with C8 to C24 hydrocarbon or the residue of misoprostol. The compounds are useful for treating rhinitis and asthma, particularly by inhalation, and for treating inflammation, particularly by local or topical administration.
Inventors:
CURRIE MARK G (US)
JONES STEVEN (US)
ZEPP CHARLES M (US)
JONES STEVEN (US)
ZEPP CHARLES M (US)
Application Number:
PCT/US2003/031923
Publication Date:
September 30, 2004
Filing Date:
October 08, 2003
Export Citation:
Assignee:
SEPRACOR INC (US)
CURRIE MARK G (US)
JONES STEVEN (US)
ZEPP CHARLES M (US)
CURRIE MARK G (US)
JONES STEVEN (US)
ZEPP CHARLES M (US)
International Classes:
A61K31/56; C07J5/00; C07J71/00; (IPC1-7): C07J5/00; C07J71/00; A61K31/573
Domestic Patent References:
| WO1992013873A1 | 1992-08-20 | |||
| WO2003070745A2 | 2003-08-28 |
Foreign References:
| US3929768A | 1975-12-30 | |||
| GB1269291A | 1972-04-06 | |||
| EP0262108A1 | 1988-03-30 | |||
| EP0164636A2 | 1985-12-18 |
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