Title:
A FERMENTATION PRODUCTION PROCESS OF L-SORBOSE WITH HIGH CONCENTRATION
Document Type and Number:
WIPO Patent Application WO/2016/062232
Kind Code:
A1
Abstract:
The present invention provides a fermentation production process of L-sorbose with high concentration, using gluconobacter melanogenus as a production strain and usi-ng D-sorbitol as the substrate, adding 0.1 mg/ml-5 mg/ml of gelatin into a seed strain liquid culture medium, and adding 0.1 mg/ml -5 mg/ml of citric acid and 0.1 mg/ml -5 mg/ml of itaconic acid in a respective or combined manner into the fermentation liquor at any time of 0-16 hours of fermentation. As a result, the content of the L-sorb-ose after the fermentation reaches more than 420 mg/ml.
Inventors:
XIAO JIANGFENG (CN)
HUANG JIANMIN (CN)
FENG LIPING (CN)
DU ERFENG (CN)
TAO HAI (CN)
ZHAO DUJUAN (CN)
HUANG JIANMIN (CN)
FENG LIPING (CN)
DU ERFENG (CN)
TAO HAI (CN)
ZHAO DUJUAN (CN)
Application Number:
PCT/CN2015/092248
Publication Date:
April 28, 2016
Filing Date:
October 20, 2015
Export Citation:
Assignee:
DSM JIANGSHAN PHARMACEUTICAL JIANGSU CO LTD (CN)
International Classes:
C12P19/02; C12R1/01
Foreign References:
| CN104357507A | 2015-02-18 | |||
| CN103114111A | 2013-05-22 | |||
| EP0728840A2 | 1996-08-28 |
Attorney, Agent or Firm:
BEIJING EAST IP LTD. (Tower E2 The Towers, Oriental Plaza,,No.1 East Chang An Ave., Dongcheng District, Beijing 8, CN)
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