Title:
FILLER FOR SIZE EXCLUSION CHROMATOGRAPHY AND METHOD FOR MANUFACTURING SAME
Document Type and Number:
WIPO Patent Application WO/2018/155241
Kind Code:
A1
Abstract:
The problem addressed by the present invention is to provide a filler that is suitable for use as a filler for size exclusion chromatography for fractionation requiring large volume processing, that can be manufactured by simple steps, and that has little pressure loss in a column even with a small particle size, and a method for manufacturing that filler. In the present invention, the filler for size exclusion chromatography is obtained by a manufacturing step that includes: a step for polymerization of glycerin-1,3-dimethacrylate and glycidyl methacrylate in the presence of a polymerization initiator; a step for hydrophilizing porous particles formed from the resultant polymer using sugar alcohol; and a step for ring-opening of the remaining glycidyl groups by mineral acid.
Inventors:
MARUTA SHUHEI (JP)
Application Number:
PCT/JP2018/004665
Publication Date:
August 30, 2018
Filing Date:
February 09, 2018
Export Citation:
Assignee:
SHOWA DENKO KK (JP)
International Classes:
B01J20/282; B01D15/34; G01N30/88
Domestic Patent References:
WO2015199196A1 | 2015-12-30 | |||
WO2006132333A1 | 2006-12-14 |
Foreign References:
JP2000074894A | 2000-03-14 | |||
JPS6138462A | 1986-02-24 | |||
JP4440771B2 | 2010-03-24 | |||
JP2012141212A | 2012-07-26 | |||
JPS6279356A | 1987-04-11 | |||
US20160068651A1 | 2016-03-10 | |||
JPS633006A | 1988-01-08 | |||
JP2010137207A | 2010-06-24 | |||
JP2012141212A | 2012-07-26 | |||
JP4440771B2 | 2010-03-24 | |||
JP2007170907A | 2007-07-05 |
Other References:
See also references of EP 3586958A4
Attorney, Agent or Firm:
SSINPAT PATENT FIRM (JP)
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