Title:
FLAVIVIRUS ENVELOPE PROTEIN MUTATIONS AFFECTING VIRION DISASSEMBLY
Document Type and Number:
WIPO Patent Application WO/2014/074535
Kind Code:
A9
Abstract:
Mutations in the central monomer contact interface of the flavivirus envelope protein which modulate the infectivity of the flavivirus are made. The mutations decrease the ability of the envelope dimer protein to dissociate.
Inventors:
YAMSHCHIKOV VLADIMIR (US)
Application Number:
PCT/US2013/068616
Publication Date:
September 04, 2014
Filing Date:
November 06, 2013
Export Citation:
Assignee:
SOUTHERN RES INST (US)
International Classes:
A61K39/12; A61P31/14; C12N7/01; C12N7/02; C12N7/04
Attorney, Agent or Firm:
SELLERS, Andrea, F. (1201 Walnut Street Suite 290, Kansas City MO, US)
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