Title:
FLAVONOID GLYCOSIDE-ORGANIC AMINE ANTIMICROBIAL AGENT DOUBLE SALT COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/089600
Kind Code:
A1
Abstract:
The present application relates to a double salt compound of flavonoid glycoside and an organic amine antimicrobial agent. The flavonoid glycoside has a structural general formula represented by the following formula (1), wherein R1-R9 are each independently selected from among -H, -OH, C1-C6 alkyl, alkoxy or substituted alkyl, and at least one among R1 and R2 is selected from -OH. The present application also relates to a preparation method for the double salt compound. The present application further relates to a pharmaceutical composition containing a therapeutically effective amount and an application thereof. Furthermore, the present application also relates to double salt nanoparticles obtained by nano-grinding the double salt compound and an application thereof.
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Inventors:
WANG HUALU (CN)
WANG LUYING (CN)
WANG LUYING (CN)
Application Number:
PCT/CN2021/127504
Publication Date:
May 05, 2022
Filing Date:
October 29, 2021
Export Citation:
Assignee:
HANGZHOU LALIN INTELLIGENCE SCIENCE AND TECH CO LTD (CN)
International Classes:
C07H17/07; A61K31/7048; A61K45/06; A61P17/00; A61P17/02; A61P19/02; A61P29/00; A61P33/06; A61P37/02; C07D401/04; C07H1/00
Foreign References:
| CN113244212A | 2021-08-13 | |||
| CN113244211A | 2021-08-13 | |||
| CN106860866A | 2017-06-20 | |||
| CN111166887A | 2020-05-19 | |||
| CN105434454A | 2016-03-30 | |||
| CN105878231A | 2016-08-24 |
Other References:
LI XIAOHUA , HUANG SHUNDE , YANG JIE: "Effects of baicalin combined with lamivudine on cellular immunity in the treatment of chronic hepatitis B", PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA, vol. 31, no. 4, 15 August 2015 (2015-08-15), pages 218 - 220, XP055927172, DOI: 10.13412/j.cnki.zyyl.2015.04.069
ZHANG YUFENG; LYU CHUNMING; FONG SOPHIA YUI KAU; WANG QIAN; LI CHENRUI; HO NICOLAS JAMES; CHAN KAY SHEUNG; YAN XIAOYU; ZUO ZHONG: "Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs", JOURNAL OF ETHNOPHARMACOLOGY, vol. 243, 17 July 2019 (2019-07-17), IE , pages 1 - 10, XP085796383, ISSN: 0378-8741, DOI: 10.1016/j.jep.2019.112097
ZHANG YUFENG; LYU CHUNMING; FONG SOPHIA YUI KAU; WANG QIAN; LI CHENRUI; HO NICOLAS JAMES; CHAN KAY SHEUNG; YAN XIAOYU; ZUO ZHONG: "Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs", JOURNAL OF ETHNOPHARMACOLOGY, vol. 243, 17 July 2019 (2019-07-17), IE , pages 1 - 10, XP085796383, ISSN: 0378-8741, DOI: 10.1016/j.jep.2019.112097
Attorney, Agent or Firm:
ACIP LAW OFFICES (CN)
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