Title:
FLOW CYTOMETER, CELL SORTER, OPTICAL INFORMATION GENERATION METHOD, AND PROGRAM
Document Type and Number:
WIPO Patent Application WO/2022/080492
Kind Code:
A1
Abstract:
This flow cytometer comprises: a light source; a microfluidic device; a photodetector; an information generation device that generates, on the basis of light signal intensity, optical information indicating the shape of an observation target; and a spatial light modulation unit that is installed on an optical path between the light source and the photodetector, and that structuralizes either illumination light radiated from the light source toward a channel, or signal light from the observation object. In a channel of the microfluidic device, a plurality of light signal detection positions are arranged linearly and at equal intervals in a prescribed direction of the channel due to the structuralization of illumination light or signal light, and a plurality of trigger signal detection positions, which are for detecting trigger signals for initiating the generation of optical information by the information generation device and which correspond to the respective optical signal detection positions, are arranged so as to be separated by an identical prescribed distance in the longitudinal direction of the channel.
Inventors:
IMAI TORU (JP)
ADACHI HIROAKI (JP)
TODA KEISUKE (JP)
ADACHI HIROAKI (JP)
TODA KEISUKE (JP)
Application Number:
PCT/JP2021/038306
Publication Date:
April 21, 2022
Filing Date:
October 15, 2021
Export Citation:
Assignee:
THINKCYTE INC (JP)
International Classes:
G01N21/53; G01N15/14; G01N21/59; G01N37/00
Domestic Patent References:
| WO2016054293A1 | 2016-04-07 | |||
| WO2019241443A1 | 2019-12-19 |
Foreign References:
| JP2019526783A | 2019-09-19 | |||
| JP2009180723A | 2009-08-13 | |||
| JP2009063308A | 2009-03-26 | |||
| US20120078531A1 | 2012-03-29 | |||
| JPS6394156A | 1988-04-25 | |||
| JP2020174037A | 2020-10-22 | |||
| JP2021110063A | 2021-08-02 | |||
| JP2011099848A | 2011-05-19 | |||
| US20170227466A1 | 2017-08-10 |
Other References:
YI GUALEX CE ZHANGYUANYUAN HANJIE LICLARK CHENYU-HWA LO: "Cytometry", 25 March 2019, INTERNATIONAL SOCIETY FOR ADVANCEMENT OF CYTOMETRY, article "Machine Learning Based Real-Time Image-Guided Cell Sorting and Classification"
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
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