Title:
FLUORINE-SUBSTITUTED TRIPTOLIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2018/019301
Kind Code:
A1
Abstract:
Provided is a compound represented by formula I, or a pharmaceutically acceptable salt, enantiomer, diastereomer, tautomer, solvate, polycrystalline material, or precursor thereof, and a manufacturing method and pharmaceutical application of same. The compound has improved immunosuppressive activity and antitumor activity, and has better development and application prospects.
Inventors:
ZHANG PENG (CN)
BAO LIXIA (CN)
LIU XIANGCHAO (CN)
HE LIJUN (CN)
XIAO FEI (CN)
BAO LIXIA (CN)
LIU XIANGCHAO (CN)
HE LIJUN (CN)
XIAO FEI (CN)
Application Number:
PCT/CN2017/094991
Publication Date:
February 01, 2018
Filing Date:
July 28, 2017
Export Citation:
Assignee:
CINKATE PHARMACEUTICAL INTERMEDIATES CO LTD (CN)
International Classes:
C07J73/00; A61K31/57; A61P35/00; A61P37/06
Domestic Patent References:
| WO2014145303A1 | 2014-09-18 | |||
| WO2005000291A1 | 2005-01-06 | |||
| WO2015085447A1 | 2015-06-18 |
Foreign References:
| CN102634561A | 2012-08-15 |
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
Download PDF: