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Title:
FLUOROGENIC DYES FOR HIGH SENSITIVITY DNA DETECTION
Document Type and Number:
WIPO Patent Application WO/2018/085449
Kind Code:
A3
Abstract:
The present disclosure is directed to unsymmetrical cyanine dyes comprising a substituted benzazolium ring system linked by a methine bridge to a quinolinium ring that contains a heteroatom. Compounds of formula (I) are provided herein. The compounds can be useful for fluorescent detection or quantification of nucleic acids. Related methods, uses, and kits are disclosed.

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Inventors:
GEE KYLE (US)
YANG JONGTAE (US)
Application Number:
PCT/US2017/059594
Publication Date:
January 31, 2019
Filing Date:
November 01, 2017
Export Citation:
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Assignee:
LIFE TECHNOLOGIES CORP (US)
International Classes:
C07D417/12; C09B23/04; C12Q1/6818
Foreign References:
US5658751A1997-08-19
US20160010145A12016-01-14
US20090068672A12009-03-12
Attorney, Agent or Firm:
POLIZOTTO, Renée S. (US)
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