Title:
FLUOROSILINATED LIQUID-INFUSED SURFACES WITH EMBEDDED BIOMOLECULES, METHODS OF MAKING AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/136560
Kind Code:
A1
Abstract:
The present application discloses biofunctional surfaces that have self-assembled monolayers of fluorine groups with "built-in" functional groups promote targeted cell and biomolecule binding to the surface while reducing non-specific binding. Further, this application also relates to methods for preparing functional biomolecules, viruses and cells that can be covalently immobilized to prepare biofunctional surfaces.
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Inventors:
DIDAR TOHID F (CA)
BADV MARYAM (CA)
CETINIC ZACHARY (CA)
SHAKERI AMID (CA)
BADV MARYAM (CA)
CETINIC ZACHARY (CA)
SHAKERI AMID (CA)
Application Number:
PCT/CA2019/050033
Publication Date:
July 18, 2019
Filing Date:
January 09, 2019
Export Citation:
Assignee:
UNIV MCMASTER (CA)
International Classes:
C07K17/14; A61L27/28; A61L27/54; A61L31/08; A61L31/16; C03C17/30; C07K1/107; C07K16/00; C07K16/28; C07K17/00; C08J7/12; C12N11/00; C12N11/14; C12N15/11; G01N33/53; G01N33/543
Domestic Patent References:
| WO2017095958A1 | 2017-06-08 | |||
| WO1992005444A1 | 1992-04-02 | |||
| WO1997022631A1 | 1997-06-26 |
Foreign References:
| US5079155A | 1992-01-07 | |||
| US5721131A | 1998-02-24 |
Other References:
BADV, M. ET AL.: "Lubricant-infused surfaces with built-in functional biomolecules exhibit simultaneous repellency and tunable cell adhesion", ACS NANO, vol. 12, no. 11, 27 November 2018 (2018-11-27), pages 10890 - 10902, XP055626304
Attorney, Agent or Firm:
BERESKIN & PARR LLP/S.E.N.C.R.L., S.R.L. (CA)
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