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Title:
FOOD MATERIAL HAVING RAGE SIGNALING INHIBITORY EFFECT
Document Type and Number:
WIPO Patent Application WO/2019/172174
Kind Code:
A1
Abstract:
[Problem] To provide a novel RAGE signaling inhibitor. [Solution] This RAGE signaling inhibitor contains, as an active ingredient, an extract from one or more plants selected from the plant group consisting of Geumjaponicum Thunb., Salvia sclarea, Boswellia serrata, Coleus forskohlii Briq., Fortunella species, Cinnamomum camphora, Salix alba, Ruscus aculeatus, Ficus pumila, Sassafras albidum, Hedychium coronarium, Claytonia perfoliata, Chenopodium album var. centrorubrum, and Carica papaya.

Inventors:
HAYASHI KENJIRO (JP)
YAMAMOTO YASUHIKO (JP)
MUNESUE SEIICHI (JP)
HARASHIMA AI (JP)
Application Number:
JP2019/008346
Publication Date:
September 12, 2019
Filing Date:
March 04, 2019
Export Citation:
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Assignee:
NIPPON SHINYAKU CO LTD (〒6018550, JP)
International Classes:
A61K36/185; A61K36/324; A61K36/53; A61K36/537; A61K36/54; A61K36/60; A61K36/73; A61K36/75; A61K36/76; A61K36/896; A61K36/906; A61P1/02; A61P1/16; A61P9/00; A61P9/10; A61P9/12; A61P9/14; A61P15/08; A61P15/10; A61P19/10; A61P25/28; A61P27/12; A61P35/00; A61P43/00; A23G3/34; A23L2/38; A23L2/52; A23L33/105
Foreign References:
JP2012529484A2012-11-22
JP2012529487A2012-11-22
JPH0249730A1990-02-20
US20090022827A12009-01-22
KR100718602B12007-05-09
JP2015155398A2015-08-27
JP2012529488A2012-11-22
CN104922395A2015-09-23
KR20090020279A2009-02-26
US20040247698A12004-12-09
Other References:
SUH, S. J. ET AL.: "3,4,5-Trihydroxybenzaldehyde From Geum japonicum Has Dual Inhibitory Effect on Matrix Metalloproteinase 9; Inhibition of Gelatinoytic Activity as well as MMP-9 Expression in TNF-a Induced HASMC", JOURNAL OF CELLULAR BIOCHEMISTRY, vol. 105, no. 2, 2008, pages 524 - 533, XP055041747, doi:10.1002/jcb.21854
XIA, S. F. ET AL.: "Niga-ichigoside F1 ameliorates high-fat diet-induced hepatic steatosis in male mice by Nrf2 activation", FOOD & FUNCTION, vol. 9, no. 2, 21 December 2017 (2017-12-21) - 1 February 2018 (2018-02-01), pages 906 - 916, XP055636775
Attorney, Agent or Firm:
NAKAMURA Ayatsugu (〒6018550, JP)
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