Title:
FORMATION OF NANOSTRUCTURED PARTICLES OF POORLY WATER SOLUBLE DRUGS AND RECOVERY BY MECHANICAL TECHNIQUES
Document Type and Number:
WIPO Patent Application WO/2009/117410
Kind Code:
A8
Abstract:
The present invention provides a composition and method of forming an amorphous drug-loaded particle by forming one or more amorphous drug-loaded nanoparticles comprising one or more active agents stabilized by one or more polymers, desolvating the one or more amorphous drug-loaded nanoparticles to form one or more flocculated amorphous drug-loaded nanoparticles, filtering the one or more flocculated amorphous drug-loaded nanoparticles and drying the one or more flocculated amorphous drug-loaded nanoparticles to form amorphous drug-loaded particles.
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Inventors:
JOHNSTON KEITH P (US)
WILLIAMS ROBERT O III (US)
MATTEUCCI MICHAL E (US)
WILLIAMS ROBERT O III (US)
MATTEUCCI MICHAL E (US)
Application Number:
PCT/US2009/037391
Publication Date:
August 12, 2010
Filing Date:
March 17, 2009
Export Citation:
Assignee:
UNIV TEXAS (US)
JOHNSTON KEITH P (US)
WILLIAMS ROBERT O III (US)
MATTEUCCI MICHAL E (US)
JOHNSTON KEITH P (US)
WILLIAMS ROBERT O III (US)
MATTEUCCI MICHAL E (US)
International Classes:
A61K9/16; A61K9/20; A61K9/50; A61K31/496; A61K47/34; C01B13/14
Attorney, Agent or Firm:
CHALKER, Daniel et al. (LLP2711 LBJ Freeway, Suite 103, Dallas TX, US)
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