Title:
FORMULATIONS OF ACTIVE PHARMACEUTICAL INGREDIENTS (APIS) FOR LOCAL DELIVERY VIA ACTIVE MICROBOT
Document Type and Number:
WIPO Patent Application WO/2022/271476
Kind Code:
A9
Abstract:
Provided herein are pharmaceutical formulations, methods of manufacturing thereof, and methods of treatment. The pharmaceutical formulations are adapted to serve as a payload on or in a microbot, and comprise a tablet of a therapeutically effective dose of a pharmaceutical agent and have dimensions such that the tablet may fit on or in the microbot. The pharmaceutical formulation may be formed into, e.g., a cylinder or spheroid of 1mm dimension, and the pharmaceutical agent may be a small molecule drug, a peptide, a peptoid, a biologic drug, cells, or any combination thereof. Thus, the pharmaceutical formulation of the present description offers delivery of targeted therapy at a locus in a subject, e.g., a tumor.
Inventors:
KISELYOV ALEX (US)
Application Number:
PCT/US2022/033256
Publication Date:
February 23, 2023
Filing Date:
June 13, 2022
Export Citation:
Assignee:
BIONAUT LABS LTD (IL)
KISELYOV ALEX (US)
KISELYOV ALEX (US)
International Classes:
A61J3/00; B65B43/42; A61J3/07; A61J7/00
Attorney, Agent or Firm:
COHEN, Mark et al. (US)
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