FRAGRANCE COMPOSITIONS AND USES THEREOF

FIELD OF THE INVENTION

The present invention relates to the field of perfumery. In particular, it provides compositions comprising fragrance materials in a diamond construction and at least one substantially non-odorous fragrance modulator for improving or enhancing the fidelity and/or longevity of the fragrance profile. The invention also relates to methods of making and using said compositions. BACKGROUND OF THE INVENTION

Conventional perfuming compositions have a fragrance profile characterized by the classical fragrance pyramid three-tiered structure, which contains a higher amount of the base notes, a medium amount of the heart notes, and a lower amount of the top notes (see Fig. la). The conventional pyramid structure is used because higher levels of the base notes are relied upon to provide the intensity of the overall fragrance profile over time and replace the heart notes when those are declining. Simply increasing the levels of heart and top notes does not provide the required longevity because of their fast evaporation.

Perfumers typically classify fragrance materials as a base, heart or top note according to their specific characters. For instance, the fragrance material "Hedione ^® " (or also known as "methyl dihydrojasmonate") is commonly classified as a heart note based on its perceived floral character. However, due to the somewhat subjective nature of characters, there has been no universal convention for objectively classifying fragrance materials. As a result of the subjective classification approach, fragrance formulation has been inconsistent. For example, two compositions having the exact same classification of fragrance materials constructed according to the classical fragrance pyramid structure could have two different, possibly very different, fragrance profiles.

With the classical fragrance pyramid structure, "base notes" make up from greater than 30 wt%, typically greater than 40 wt% or typically greater than 50 wt%, relative to the total weight of the perfume formulation. Base notes are characterized by providing animalic, woody, sweet, amber or musky characters, and not being very volatile. The "heart or middle notes", make up from about 0.1 wt% to about 60 wt% relative to the total weight of the perfume formulation and have an intermediate volatility. Heart notes are associated with desirable characters such as floral characters (e.g., jasmin, rose), fruity, marine, aromatic or spicy characters. The "top or head notes" provide citrusy, green, light, or fresh characters, and make up from about 0.1 wt% to about 40 wt% relative to the total weight of the perfume formulation. Top notes tend to evaporate quickly due to their high volatility.

There are at least one of several drawbacks to the above described classical formulation approach. Firstly, classification of fragrance materials by their characters is subjective and therefore results in inconsistency in the fragrance profile under classical fragrance pyramid construction rules. Secondly, the perceived intensity of the fragrance profile of the conventional perfume compositions, particularly those characters attributable to the more volatile fragrance materials, decreases rapidly over time due to their quick evaporation. Accordingly, conventional perfume compositions will typically change their overall fragrance profile over time. This is a problem because it is desirable to maintain "fragrance profile fidelity" over time. In other words, it is desirable to maintain the same or substantively similar fragrance profile for a commercial fragrance over time, particularly over long periods of time (at least 4 hrs, 6 hrs, or even 8 hours after application). Thirdly, with the classical fragrance pyramid construction, the possible types of fragrance profiles have been somewhat limited. The consequence of using base notes at high levels is that many fragrance dry-downs appear repetitive, boring, non-memorable and uninteresting to consumers. However, if base notes are reduced or excluded then the fragrance intensity weakens over time and does not last for a sufficient duration. Lastly, it is generally accepted that some consumers desire prolonged intensity of select characters, particularly the floral, spicy or aromatic characters derived from the heart notes. Unfortunately, the consequence of using high levels of base notes is that they may impart particularly undesirable characters, such as for example, musky, woody, ambery, warm and sweet, which overpower and dominate the more desirable fragrance characters over time, particular over long periods of time. Thus, the unique challenge remains of selectively extending the more desirable characters attributable from the heart and/or top notes, particularly the heart notes, and even more particularly extending these desirable characters over long periods of time.

Previous attempts to overcome these problems have been through the use of various "fixatives" or "modulators" to retard the evaporation of the more volatile fragrance ingredients present in fragrance compositions. For instance, U.S. Patent No. 6,737, 396B2 (Firmenich) describes a perfume composition formed by mixing 2-30%, relative to the weight of the composition, of a fixative, (l-ethoxyethoxy)cyclododecane, to fix or exalt the musky or aromatic-type notes. U.S. Patent No. 6,440,400B1 (Takasago Perfumery) describes a composition using trimethylcyclohexane derivatives as perfuming-holding agents and melanin- formation inhibitors. U.S. Patent No. 4,313,855 (Dragoco) describes the use in cosmetic compositions of l-(2,6,6-trimethylcyclohexyl)-hexane-3-ol as an odourless fixative for increasing the perfume's intensity. U.S. Patent No. 6,147,049 (Givaudan) discloses a perfume fixative derived from tera-hydronaphthalenese for use in a wide range of fragrance compositions. WO85/04803 (Diagnostica) describes the use of hyaluronic acid/ hyaluronate as fixatives (via molecular encapsulation) in fragrance products to improve persistent of the fragrance. JP Patent No. 61-083114 (Kanebo) describes ether derivatives as aroma-preserving agent for fine perfume composition. JP Patent No. 61-063612 (Kanebo) discloses diethylene glycol ether derivatives as fragrance adjusting agent showing effects as a fixative and a solubilizer. JP Patent No. 62- 084010 (Shiseido) describes hydroquinone glycoside as perfume fixatives applicable for all kinds of perfume and blended perfume. U.S. Patent No. 7,196,052 (Takasago Int. Corp.) describes fragrance compositions containing glycerol ether derivatives as fixatives or fragrance note-improving agent. EP Patent Publication No. 616800A2 (Givaudan) discloses odourant compositions containing panethenol ethyl ether having improved prolonged diffusion of the perfume materials from the skin, without notably modifying the olfactive note of the product. U.S. Patent No. 4,110,626 (Shiseido) describes the use of aliphatic dibasic acid diester as "perfume controlling agent" for improved fixing effect on fragrance component. PCT Publication No. WO2014/155019 (LVMH) describes aliphatic ether derivatives to increase the stability of alcoholic fragrance composition and more particularly to preserve the original olfactive notes.

These attempts have advocated the use of such fixatives or modulators indiscriminately without regard to the fragrance profile. Further, these attempts do not teach how to objectively classify the fragrance materials as low, moderate or high volatile fragrance materials. Further, the use of fixatives or modulators in these attempts often shows effects on single fragrance material, which are often not observed in a fragrance composition of a mixture of fragrance materials where a number of such fragrance materials are competing with each other to interact with said fixatives or modulators. They do not teach how to formulate with fixatives or modulators in fragrance mixtures, which is not trivial. As a result, these attempts, while disclosing compositions that retain the perfume by way of fixatives or modulators, neither teach the fragrance diamond construction in compositions nor the particular type or levels of fragrance materials to include for delivering the benefits of improved fidelity to the perceived fragrance profile over time, or improved longevity of the fragrance profile, preferably the characters attributable from the moderate or high volatile fragrance materials, particularly the moderate volatile fragrance materials.

On the other hand, other attempts propose a selective approach aimed at the selection of specific fixatives or modulators and defined amounts of fragrance materials. For instance, U.S. Patent No. 7,538,081 (Takasago Perfumery) approaches the problem of fixing a perfume and/or extending the perfume release from a fragrance composition. More particularly, said document describes the use of L-menthoxy ether derivatives as fixatives in fragrance compositions comprising at least one note selected from: floral, citrus, fruity, green, mint, herb and marine. U.S. Patent Publication No. 2011/0104089A1 (Symrise) describes certain compositions containing neopentyl glycol diisononanoate as a fixative for top note perfume oils by increasing their adhereance to skin and hair. U.S. Patent Publication No. 2011/0091404 (Symrise) discloses the use of N-hexadecyl n-nonanoate and N-octadecyl n-nonanoate as fixatives of fragrance substances, particularly the readily volatile top notes, by lowering their vapor pressure to allow for a time-delayed release of the perfume oil components from a composition.

However, these attempts tend not to describe how to formulate with fixatives or modulators in complex mixtures of fragrance materials. For those references that do describe mixtures of fragrance materials, they have different fragrance design criteria and are directed to specific preferred fixatives or modulators.

SUMMARY OF THE INVENTION

The inventors have discovered new rules for objectively classifying fragrance materials according to their vapor pressures into low, moderate and high volatile fragrance materials for formulating into fragrance mixtures, preferably complex mixtures having a diamond construction.

In a first aspect, the present invention is directed to a composition comprising a diamond construction fragrance formulation (see Fig. lb) and at least one substantially non-odorous fragrance modulator for delivering enhanced intensity of the perceived fragrance profile over time, preferably the components attributable from the moderate and high volatile fragrance materials. In particular, the present invention is directed to a composition comprising: (i) a fragrance component present in an amount of from about 0.04 wt% to about 30 wt%, relative to the total weight of the composition; (ii) at least one substantially non-odorous fragrance modulator present in the amount of from about 0.1 wt% to about 20 wt%, relative to the total weight of the composition; (iii) a volatile solvent present in an amount of from about 50 wt% to about 80 wt%, relative to the total weight of the composition; and (iv) optionally water. The fragrance component comprises: (a) at least one low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C present in an amount of from about 10 wt% to about 30 wt%, relative to the total weight of the fragrance component; (b) at least one moderate volatile fragrance material having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C present in an amount of from about 40 wt% to about 80 wt%, relative to the total weight of the fragrance component; and (c) at least one high volatile fragrance material having a vapor pressure greater than 0.1 Torr (0.0133 kPa) at 25 °C present in an amount of from about 1 wt% to about 30 wt%, relative to the total weight of the fragrance component.

In another aspect, the present invention is directed to a method for imparting, intensifying, or modifying an odour on human skin or human hair, comprising applying to human skin and/or human hair with the composition of the present invention.

Thus, it is an advantage of the present invention to provide new rules for objectively classifying fragrance materials according to their volatility using their their vapor pressures defined at suitable temperature, instead of their characters. The new rules operate irrespective of perfumers performing the classification. In particular, the new rules classify the fragrance materials into low, moderate or high volatile fragrance materials for formulating into fragrance mixtures, particularly ones having a diamond construction. It is a further advantage of the present invention to provide compositions having improved fidelity to the perceived fragrance profile over time. It is yet a further advantage to provide a composition, wherein the character attributable to moderate and high volatile fragrance materials, particularly the moderate volatile fragrance materials, remains significantly consistent from its initial impression to the end. It is yet a further advantage to provide compositions having improved longevity of the perceived fragrance profile, preferably the characters attributable from the moderate or high volatile fragrance materials, particularly the moderate volatile fragrance material. It is yet a further advantage to provide compositions having stable quality of end product (e.g., fragrance profile, visual appearance) substantially comparable to the classical fragrance pyramid three-tiered structure, preferably even after three months storage at 40 °C. It is yet a further advantage to be able to create new to the world fragrance profiles wherein one, or several, well-recognized moderate volatile fragrance material characters, are maintained over time, preferably for long periods of time (e.g., greater than 4, 6, or even 8 hours).

These and other features of the present invention will become apparent to one skilled in the art upon review of the following detailed description when taken in conjunction with the appended claims.

BRIEF DESCRIPTION OF THE DRAWINGS

While the specification concludes with claims particularly pointing out and distinctly claiming the invention, it is believed that the invention will be better understood from the following description of the accompanying figures wherein:

Figure la is a diagram of the classical fragrance pyramid structure of the prior art.

Figure lb is a diagram of a fragrance diamond construction according to an embodiment of the present invention.

Figure 2 provides the panel test results of perceived fragrance profile, particularly improved fragrance profile longevity of Composition A9 comprising Indocolore fragrance material and Expert Gel ^® 56 substantially non-odorous fragrance modulator as compared to Composition B9, a control absent of a substantially non-odorous fragrance modulator (Expert Gel ^® 56), and as a function of time elapsed since application of the composition.

Figure 3 provides the panel test results of perceived fragrance profile, particularly improved fragrance profile longevity of Composition C9 comprising Dimethyl Benzyl Carbinol fragrance material and Kolliphor ^® EL substantially non-odorous fragrance modulator as compared to Composition D9, a control absent of a substantially non-odorous fragrance modulator (Kolliphor ^® EL), and as a function of time elapsed since application of the composition. Figure 4 provides the panel test results of perceived fragrance profile, particularly improved fragrance profile longevity of Composition E9 comprising Eugenol fragrance material and Kolliphor ^® EL substantially non-odorous fragrance modulator as compared to Composition F9, a control absent of a substantially non-odorous fragrance modulator (Kolliphor ^® EL), and as a function of time elapsed since application of the composition.

Figure 5 provides the panel test results of perceived fragrance profile, particularly improved fragrance profile longevity of Composition G9 comprising Phenethyl alcohol (PEA) fragrance material and Kolliphor ^® EL substantially non-odorous fragrance modulator as compared to Composition H9, a control absent of a substantially non-odorous fragrance modulator (Kolliphor ^® EL), and as a function of time elapsed since application of the composition.

Figure 6 provides the panel test results of the fragrance profile longevity, particularly intensity of the character attributable to the volatile fragrance materials, of Composition A4 comprising Diamond Floral Magnifica Fragrance Example 4b, and PPG-20 Methyl Glucose Ether (i.e., Glucam™ P-20) substantially non-odorous fragrance modulator as compared to Composition C4, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 7 provides the panel test results of the fragrance profile longevity, particularly intensity of the character attributable to the volatile fragrance materials, of Composition A4 comprising Diamond Muguesia Magnifica Fragrance Example 5b, and PPG-20 Methyl Glucose Ether (i.e., Glucam™ P-20) substantially non-odorous fragrance modulator as compared to Composition C4, comprising Traditional Muguesia Magnifica Fragrance Example 5a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 8 provides the panel test results of the fragrance profile longevity, particularly intensity of the character attributable to the volatile fragrance materials, of Composition A2 comprising Diamond Floral Magnifica Fragrance Example 4b, and Diisobutyl Adipate substantially non-odorous fragrance modulator as compared to Composition C2, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition. Figure 9 provides the panel test results of the fragrance profile longevity, particularly intensity of the character attributable to the volatile fragrance materials, of Composition A2 comprising Diamond Muguesia Magnifica Fragrance Example 5b, and Diisobutyl Adipate substantially non-odorous fragrance modulator as compared to Composition C2, comprising Traditional Muguesia Magnifica Fragrance Example 5a, and absent of a substantially non- odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 10 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition A4 comprising Diamond Floral Magnifica Fragrance Example 4b, and PPG-20 Methyl Glucose Ether (i.e., Glucam™ P-20) substantially non-odorous fragrance modulator as compared to Composition C4, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 11 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition A4 comprising Diamond Muguesia Magnifica Fragrance Example 5b, and PPG-20 Methyl Glucose Ether (i.e., Glucam™ P-20) substantially non-odorous fragrance modulator as compared to Composition C4, comprising Traditional Muguesia Magnifica Fragrance Example 5a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 12 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition D4 comprising Diamond Floral Magnifica Fragrance Example 4b, and Caprylyl/Capryl Glucoside (i.e., Plantacare ^® 810 UP) substantially non-odorous fragrance modulator as compared to Composition F4, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 13 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition G4 comprising Diamond Floral Magnifica Fragrance Example 4b, and Undecyl Glucoside (i.e., Simulsol SL 11W) substantially non-odorous fragrance modulator as compared to Composition 14, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 14 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition J4 comprising Diamond Floral Magnifica Fragrance Example 4b, and Isocetyl Alcohol (i.e., Ceraphyl ^® ICA) substantially non-odorous fragrance modulator as compared to Composition L4, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 15 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition A2 comprising Diamond Floral Magnifica Fragrance Example 4b, and Diisobutyl Adipate substantially non-odorous fragrance modulator as compared to Composition C2, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 16 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition A2 comprising Diamond Muguesia Magnifica Fragrance Example 5b, and Diisobutyl Adipate substantially non-odorous fragrance modulator as compared to Composition C2, comprising Traditional Muguesia Magnifica Fragrance Example 5a, and absent of a substantially non- odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 17 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition J2 comprising Diamond Floral Magnifica Fragrance Example 4b, and PPG- 11 Stearyl Ether substantially non-odorous fragrance modulator as compared to Composition L2, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator, and as a function of time elapsed since application of the composition. Figure 18 provides the panel test results of fragrance profile fidelity, particularly the dominance of the floral character attributable to the volatile fragrance materials, of Composition J2 comprising Diamond Muguesia Magnifica Fragrance Example 5b, and PPG- 11 Stearyl Ether substantially non-odorous fragrance modulator as compared to Composition L2, comprising Traditional Muguesia Magnifica Fragrance Example 5a, and absent of a substantially non- odorous fragrance modulator, and as a function of time elapsed since application of the composition.

Figure 19 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MODI) comprising a volatile fragrance mixture and PPG-3 Myristyl Ether (i.e., Tegosoft ^® APM) substantially non-odorous fragrance modulator as compared to a control composition (REF), and as a function of time elapsed since application of the composition.

Figure 20 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD2) comprising a volatile fragrance mixture and Neopentyl Glycol Diethylhexanoate (i.e., Scherecemol™ NGDO) substantially non-odorous fragrance modulator as compared to a control composition (REF), and as a function of time elapsed since application of the composition.

Figure 21 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD3) comprising a volatile fragrance material mixture and Kolliphor ^® EL substantially non-odorous fragrance modulator as compared to a control composition (REF), and as a function of time elapsed since application of the composition.

Figures 22(a)(i) and 22(a)(ii) provide the headspace chromatography of the fragrance profile of Composition L2, comprising Traditional Muguesia Magnifica Fragrance Example 5a, and absent of a substantially non-odorous fragrance modulator as a function of time elapsed, after 10 mins and 60 mins evaporation, respectively.

Figures 22(b)(i) and 22(b)(ii) provide the headspace chromatography of the fragrance profile of Composition J2 comprising Diamond Muguesia Magnifica Fragrance Example 5b, and PPG- 11 Stearyl Ether substantially non-odorous fragrance modulator as a function of time elapsed, after 10 mins and 60 mins evaporation, respectively.

Figures 23(a)(i) and 23(a)(ii) provide the headspace chromatography of the fragrance profile of Composition C4, comprising Traditional Muguesia Magnifica Fragrance Example 5a, and absent of a substantially non-odorous fragrance modulator as a function of time elapsed, after 10 mins and 60 mins evaporation, respectively.

Figures 23(b)(i) and 23(b)(ii) provide the headspace chromatography of the fragrance profile of Composition A4 comprising Diamond Muguesia Magnifica Fragrance Example 5b, and PPG-20 Methyl Glucose Ether (i.e., GLUCAM™ P-20) substantially non-odorous fragrance modulator as a function of time elapsed, after 10 mins and 60 mins evaporation, respectively.

Figures 24(a)(i) and 24(a)(ii) provide the headspace chromatography of the fragrance profile of Composition L4, comprising Traditional Floral Magnifica Fragrance Example 4a, and absent of a substantially non-odorous fragrance modulator as a function of time elapsed, after 10 mins and 60 mins evaporation, respectively.

Figures 24(b)(i) and 24(b)(ii) provide the headspace chromatography of the fragrance profile of Composition J4 comprising Diamond Floral Magnifica Fragrance Example 4b, and Isocetyl Alcohol (i.e., Ceraphyl ^® ICA) substantially non-odorous fragrance modulator as a function of time elapsed, after 10 mins and 60 mins evaporation, respectively.

Figures 25(a)(i) and 25(a)(ii) provides the headspace chromatography of the fragrance profile of Composition 14, comprising Traditional Muguesia Magnifica Fragrance Example 5a, and absent of a substantially non-odorous fragrance modulator as a function of time elapsed, after 10 mins and 60 mins evaporation, respectively.

Figures 25(b)(i) and 25(b)(ii) provide the headspace chromatography of the fragrance profile of Composition G4 comprising Diamond Muguesia Magnifica Fragrance Example 5b, and Undecyl Glucoside (i.e., Simulsol ^® SL 11W) substantially non-odorous fragrance modulator as a function of time elapsed, after 10 mins and 60 mins evaporation, respectively.

DETAILED DESCRIPTION OF THE INVENTION

Definitions

As used herein, articles such as "a" and "an" when used in a claim, are understood to mean one or more of what is claimed or described.

As used herein, the terms "include", "includes" and "including" are meant to be non- limiting. As used herein, the term "body splash" means a body care formulation that is applied to the body. Typically, the body splash is applied to the body after bathing and provides a subtle hint of scent to the body. Body splashes are commonly used by consumers who prefer less strong fragrance compositions. A body splash may comprise an ethanol-free composition according to the present invention which comprises from 0.2-8 wt%, relative to the total weight of the composition, of a fragrance component. The body splash may further comprise alkyl polyglucosides as non-ionic surfactants.

As used herein, the term "body spray" means a formulation comprising fragrance materials intended to be applied to the body to prevent or mask body odor caused by the bacterial breakdown of perspiration on the body (e.g., armpits, feet, and other areas of the body). The body spray may also provide a fragrance expression to the consumers. Typically, body spray compositions are applied as an aerosol spray in an effective amount on the skin of a consumer.

As used herein, the term "composition" includes a fine fragrance composition intended for application to a body surface, such as for example, skin or hair, i.e., to impart a pleasant odor thereto, or cover a malodour thereof. They are generally in the form of perfume concentrates, perfumes, eau de parfums, eau de toilettes, aftershaves, or colognes. The fine fragrance compositions may be an ethanol-based composition. The term "composition" may also include a cosmetic composition, which comprises a fragrance material for the purposes of delivering a pleasant smell to drive consumer acceptance of the cosmetic composition. The term "composition" may also include body splashes or body sprays. The term "composition" may also include cleaning compositions, such as fabric care composition or home care compositions, including air care compositions (e.g., air freshners), for use on clothing or other substrates such as hard surfaces (e.g., dishes, floors, countertops). Additional non-limiting examples of "composition" may also include facial or body powder, deodorant, foundation, body/facial oil, mousse, creams (e.g., cold creams), waxes, sunscreens and blocks, bath and shower gels, lip balms, self-tanning compositions , masks and patches.

As used herein, the term "consumer" means both the user of the composition and the observer nearby or around the user.

As used herein, the term "diamond construction" means a fragrance formulation as shown in Fig. lb. In particular, the diamond construction relates to the relative weight % of the fragrance materials classified according to their vapor pressure category (i.e., low, moderate or high). A diamond constructed fragrance has a substantially greater amount of the perfume raw materials of a moderate volatility as comparied to the low and high volatile fragrance materials.

As used herein, the term "fragrance material" and "fragrance materials" relates to a perfume raw material ("PRM"), or a mixture of perfume raw materials ("PRMs"), that are used to impart an overall pleasant odour or fragrance profile to a composition. "Fragrance materials" can encompass any suitable perfume raw materials for fragrance uses, including materials such as, for example, alcohols, aldehydes, ketones, esters, ethers, acetates, nitriles, terpene hydrocarbons, nitrogenous or sulfurous heterocyclic compounds and essential oils. However, naturally occurring plant and animal oils and exudates comprising complex mixtures of various chemical components are also know for use as "fragrance materials". The individual perfume raw materials which comprise a known natural oil can be found by reference to Journals commonly used by those skilled in the art such as "Perfume and Flavourist" or "Journal of Essential Oil Research", or listed in reference texts such as the book by S. Arctander, Perfume and Flavor Chemicals, 1969, Montclair, New Jersey, USA and more recently re-publisehd by Allured Publishing Corporation Illinois (1994). Additionally, some perfume raw materials are supplied by the fragrance houses (Firmenich, International Flavors & Fragrances, Givaudan, Symrise) as mixtures in the form of proprietary speciality accords. Non-limiting examples of the fragrance materials useful herein include pro-fragrances such as acetal pro-fragrances, ketal pro-fragrances, ester pro-fragrances, hydrolyzable inorganic-organic pro-fragrances, and mixtures thereof. The fragrance materials may be released from the pro-fragrances in a number of ways. For example, the fragrance may be released as a result of simple hydrolysis, or by a shift in an equilibrium reaction, or by a pH-change, or by enzymatic release.

As used herein, the term "fragrance profile" means the description of how the fragrance is perceived by the human nose at any moment in time. The fragrance profile may change over time. It is a result of the combination of the low, moderate and high volatile fragrance materials, if present, of a fragrance. A fragrance profile is composed of 2 characteristics: 'intensity' and 'character'. The 'intensity' relates to the perceived strength whilst 'character' refers to the odour impression or quality of the perfume, i.e., fruity, floral, woody, etc.

As used herein, the terms "modulator", and "fragrance modulator" are used interchangeably to designate an agent having the capacity to affect the fragrance profile, such as for example, by impacting the fragrance materials' evaporation rate. The modulator may mediate its effect by lowering the vapor pressure of the fragrance materials and increasing their adherence to the substrate (skin and/or hair) thus ensuring a longer-lasting impression of the fragrance. By incorporating the modulator, it is desired that the fragrance profile, preferably the fragrance components of the diamond construction attributable to the moderate and high volatile fragrance materials of the composition can be perceived by a consumer, over a longer period of time, as compared to the same perception in the absence of the fragrance diamond construction and the modulator. Suitable examples of the modulator are provided herein below. However, as discovered by the inventors, simply adding modulators to a traditionally constructed fragrance composition (i.e., classical fragrance pyramid construction) will not ensure an improved or enhanced fidelity and/or longevity of the fragrance profile over time. Instead, it is only when the modulators are added in the presence of the fragrance diamond construction can the improved or enhanced fidelity and/or longevity of the fragrance profile, preferably attributable to the moderate and high volatile fragrance materials, be perceived as compared to control composition absent the fragrance diamond construction and modulators.

As used herein, the term "substantially non-odorous" means an agent that does not impart an odour of its own when added into a composition of the present invention. For example, a "substantially non-odorous fragrance modulator" does not impart a new odour that alters the character of the fragrance profile of the composition to which it is added. The term "substantially non-odorous" also encompasses an agent that may impart a minimal or slight odour of its own when added into a composition of the present invention. However, the odour imparted by the "substantially non-odorous fragrance modulator" is generally undetectable or tends to not substantively alter the character of the fragrance profile of the composition to which it is added initially or preferably over time. Furthermore, the term "substantially non-odorous" also includes materials that are perceivable only by a minority of people or those materials deemed "anosmic" to the majority of people. Furthermore, the term "substantially non-odorous" also includes materials that may, from particular suppliers, contain an odour due to impurities, such as when the materials contain the impurities at not more than about 5 wt%, preferably not more than 1 wt%, often even not more than 1 part per million (ppm). These impurities maybe removed by purification techniques known in the art as required to make them suitable for use in fragrance compositions of the present invention. As used herein, the term "vapor pressure" means the partial pressure in air at a defined temperature (e.g., 25 °C) and standard atmospheric pressure (760 mmHg) for a given chemical species. It defines a chemical species' desire to be in the gas phase rather than the liquid or solid state. The higher the vapor pressure the greater the proportion of the material that will, at equilibrium, be found in a closed headspace. It is also related to the rate of evaporation of a fragrance material which is defined in an open environment where material is leaving the system. The vapor pressure is determined according to the reference program Advanced Chemistry Development (ACD/Labs) Software Version 14.02, or preferably the latest version update).

It is understood that the test methods that are disclosed in the Test Methods Section of the present application must be used to determine the respective values of the parameters of Applicants' inventions as described and claimed herein.

In all embodiments of the present invention, all percentages are by weight of the total composition, as evident by the context, unless specifically stated otherwise. All ratios are weight ratios, unless specifically stated otherwise, and all measurements are made at 25 °C, unless otherwise designated.

Compositions

The inventors have surprisingly discovered a revolutionary new way of objectively classifying fragrance materials and then formulating those fragrance materials into complex fragrance mixtures having improved fragrance profile fidelity and longevity. Essentially, the solution is to formulate the fragrance materials into a diamond construction in the presence of a substantially non-odorous fragrance modulator to provide for improved or enhanced longevity and/or fidelity of the fragrance profile, particularly amongst characters derived from the more volatile fragrance materials (i.e., moderate and high vapor pressure range of the perfumer's palette). In fact, the inventors have discovered that in the complete absence of the low volatile fragrance materials or at very low levels of the low volatilie fragrance materials (less than 10wt% relative to the total weight of the fragrance component) there is insufficient character complexity and roundness of the fragrance profile for consumer acceptance of the composition. Therefore the level of low volatile fragrance materials needs to be carefully chosen between 10 wt% and 30 wt%, relative to the total weight of the fragrance component, to balance consumer acceptance and the desired improved or enhanced longevity and/or fidelity of the fragrance profile, particularly amongst characters attributable to the moderate and/or high volatile fragrance materials.

Unlike previous proposed classification of fragrance materials according to their characteristic characters, which tends to be subjective, the inventors have established new rules to objectively classifying fragrance materials into low, moderate or high volatile fragrance materials according to their volatility using their vapor pressures defined at a suitable temperature. For example, methyl dihydrojasmonate which has been typically classified as a heart note under the traditional approach is now classified as a low volatile fragrance material because it has a vapor pressure of 0.00071000 Torr (0.000095 kPa) at 25 °C. This new classification better reflects methyl dihydrojasmonate's technical properties of slow evaporation and long lasting.

Also unlike previous proposed uses of modulators to enhance fragrance profile, the inventors have established that the improved aforementioned advantages are not tied to a particular modulator of specific nature/structure but can be reapplied broadly. In fact, what the inventors have established is a systematic approach for providing longer lasting fragrance profiles that is totally unexpected and advantageous contribution to the perfumery technology.

Specifically, in one aspect, the present invention provides for a composition comprising a fragrance component present in an amount of from about 0.04 wt% to 30 wt%, preferably 1 wt% to about 30 wt%, more preferably less than about 25 wt%, yet more preferably less than about 20 wt%, yet even more preferably less than about 15 wt%, yet even more preferably less than about 10 wt% or most preferably less than about 8 wt%, relative to the total weight of the composition. Alternatively, the fragrance component is present in an amount of from about 0.04 wt%, 0.3 wt%, 1 wt%, 8 wt% or 10 wt%, to about 15 wt%, 20 wt%, 25 wt% or 30 wt%, relative to the total weight of the composition. (i) Low Volatile Fragrance Materials

The fragrance component comprises at least one low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C. Preferably the composition according to the present invention comprises at least 3 low volatile fragrance materials, or at least 5 low volatile fragrance materials, or at least 7 low volatile fragrance materials. It is preferred that the composition of the present invention comprises low, preferably very low levels of the low volatile fragrance materials, lower than would traditionally be present in a fragrance pyramid three-tiered structure. As such, compositions of the present invention can comprise low levels of the low volatile fragrance material present in an amount of from about 10 wt% to about 30 wt%, preferably less than about 30 wt%, or preferably less than about 29 wt%, or preferably less than about 28 wt%, or preferably less than about 27 wt%, or preferably less than about 26 wt%, or preferably less than about 25 wt%, relative to the total weight of the fragrance component. Alternatively, the low volatile fragrance material is present in an amount of from about 10 wt%, 12 wt%, 15 wt%, 20 wt%, 25 wt% or 30 wt%, relative to the total weight of the fragrance component. If there is more than one low volatile fragrance materials, then the ranges provided hereinabove cover the total of all of the low volatile fragrance materials. Preferable examples of low volatile fragrances materials are provided in Table 1 below.

(ii) Moderate Volatile Fragrance Materials

The fragrance component comprises at least one moderate volatile fragrance material having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C. Preferably the composition according to the present invention comprises at least 3 moderate volatile fragrance materials, or at least 5 moderate volatile fragrance materials, or at least 7 moderate volatile fragrance materials. It is preferred that the composition of the present invention comprises high, preferably higher levels of the moderate volatile fragrance materials than would traditionally be present in a fragrance pyramid three-tiered structure. As such, compositions of the present invention can comprise high levels of the moderate volatile fragrance materials present in an amount of from about 40 wt% to about 80 wt%, preferably at least about 45 wt%, or preferably at least about 50 wt%, or preferably at least about 55 wt%, or preferably at least about 60 wt%, or preferably at least about 65 wt%, relative to the total weight of the fragrance component. Alternatively, the moderate volatile fragrance material is present in an amount less than about 75 wt%, or preferably less than 72 wt%, or preferably less than 70 wt%, relative to the total weight of the fragrance component. If there is more than one moderate volatile fragrance materials, then the ranges provided hereinabove cover the total of all of the moderate volatile fragrance materials. Preferable examples of modrate volatile fragrances materials are provided in Table 2 below. (iii) High Volatile Fragrance Materials The fragrance component comprises at least one high volatile fragrance material having a vapor pressure greater than 0.1 Torr (0.0133 kPa) at 25 °C. Preferably the composition according to the present invention comprises at least 3 high volatile fragrance materials, or at least 5 high volatile fragrance materials, or at least 7 high volatile fragrance materials. It is preferred that the composition of the present invention comprises high volatile fragrance materials present in an amount of from about 1 wt% to about 30 wt%, preferably less than about 25 wt%, or preferably less than about 22 wt%, or preferably less than about 20 wt%, relative to the total weight of the fragrance component. Alternatively, the low volatile fragrance material is present in an amount of from about 6 wt%, 8 wt%, 10 wt%, 12 wt %, 14 wt% or 16 wt% relative to the total weight of the fragrance component. If there is more than one high volatile fragrance materials, then the ranges provided hereinabove cover the total of all of the high volatile fragrance materials. Preferable examples of high volatile fragrances materials are provided in Table 3 below.

(iv) Fragrance Modulators

The composition further comprises at least one substantially non-odorous fragrance modulator as described herein below. Preferable examples of the substantially non-odorous fragrance modulators are provided in Table 4 below.

Preferably, the substantially non-odorous fragrance modulator is present in an amount of from about 0.1 wt% to about 20 wt%, preferably from about 0.5 wt% to about 18 wt% or more preferably from about 2.5 wt% to about 15 wt% or combinations thereof, relative to the total weight of the composition. Alternatively, the substantially non-odorous fragrance modulator is present in an amount of from about 0.1 wt%, 0.5 wt% or 2.5 wt% to about 15 wt%, 18 wt% or 20 wt%, relative to the total weight of the composition. If there is more than one substantially non- odorous fragrance modulators, then the ranges provided hereinabove cover the total of all of the substantially non-odorous fragrance modulators.

The substantially non-odorous fragrance modulator of the present invention may be a liquid at temperatures lower than 100 °C, preferably at ambient temperature. The substantially non-odorous fragrance modulators may be fully miscible with the fragrance materials to form a single phase liquid. However, if the fragrance materials are not entirely miscible, or are immiscible, then co-solvents (e.g., dipropylene glycol (DPG), triethyl citrate, or others as well known to those skilled in the art) can be added to aid in the solubility of the fragrance materials. Preferably, the composition according to the present invention, wherein the substantially non-odorous fragrance modulator does not comprise: (i) isocetyl alcohol, PPG-3 myristyl ether, neopentyl glycol diethylhexanoate or their mixtures; and (ii) n-hexadecyl n-nonanoate, n- octadecyl n-nonanoate or their mixtures.

Preferably, the composition according to the present invention, wherein the substantially non-odorous fragrance modulator and fragrance component are present in a weight ratio from about 3:1 to about 1:3.

The inventors have surprisingly discovered that by formulating the fragrance component into a diamond construction in a composition, the effect of the substantially non-odorous fragrance modulator on the fragrance profile, particularly the characters of the fragrance profile which is attributable to the moderate and high volatile fragrance materials, preferably the moderate volatile fragrace materials, can be improved. By "improved" it is meant that the fragrance profile of the composition, particular the components contributed by the moderate and high volatile fragrance materials, can be perceived by the consumer at later time points such as, for example, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 7 hours, 8 hours, 10 hours, and possibly all the way up to 24 hrs after application as compared to controls, i.e., compositions containing the classical fragrance pyramid three-tiered structure and the substantially non-odorous fragrance modulator or compositions containing the classical fragrance pyramid three-tiered structure and no substantially non-odorous fragrance modulator.

Alternatively, by "improved" it can mean that the perception, by the consumer, of the fidelity of the fragrance profile contributed by the moderate and high volatile fragrance materials is markedly increased or enhanced as compared to the controls. "Increased" or "enhanced" means that the consumer perceives the fragrance profile, preferably the characters attributable to the moderate and/or high volatile fragrance materials, of a composition as not changing from its initial impression or the changes are minimal from when the composition was first applied to when it dissipates. In other words, the fidelity of the perceived fragrance profile of the composition is maintained over time.

Typically, it has been very difficult to formulate fragrance profile, particularly a floral or spicy character of the moderate volatile fragrance materials, which can last for very long periods, especially throughout the life of the composition after its application, without giving way to the stronger characters of the low volatile fragrance materials. The present invention of the diamond construction of fragrance materials with the substantially non-odorous fragrance modulators allows perfumers to increase the olfactive perception of the moderate and high volatile fragrance materials, particularly the moderate volatile fragrance materials, to create new characters and address a re-occurring consumer issue that particular fragrance profiles, particularly those having floral or aromatic and spicy characters, do not last long enough.

Such a solution as presented herein provides enhanced or improved fidelity and/or longevity of the fragrance profile, particularly amongst those composition formulated from volatile fragrance materials having moderate to high vapor pressure ranges (greater than or equal to 0.001 Torr (0.000133 kPa) at 25 °C), without having to rely on the presence or significant amounts of the low volatile fragrance materials, which has a tendency to overpower and alter the overall fragrance profile, particularly over time. As a result, the present invention provides the perfumer options to formulate compositions having new fragrance profiles not possible before. Volatile Solvents

The present invention provides the solution to the problem of extending the longevity of the fragrance profile of compositions, particularly fine fragrance and cosmetic compositions, preferably fine fragrance compositions, which commonly contain high levels of a volatile solvent. Preferably, the composition according to the present invention, further comprising a volatile solvent present in the amount of from about 50 wt% to about 80 wt%, or preferably from about 55 wt% to about 75 wt%, relative to the total weight of the composition, and wherein the solvent is a branch or unbranched Ci to Cio alkyl, akenyl or alkynyl group having at least one alcohol moiety, preferably ethanol, or isopropanol, or other alcohols (e.g., methanol, propanol, isopropanol, butanol, and mixtures thereof) commonly found in commercial fine fragrance products.

Accordingly, ethanol may be present in any of the compositions of the present invention, and more specifically, it will form from about 10 wt% to about 80 wt%, or even from about 25 wt% to about 75 wt% of the composition, or combinations thereof, relative to the total weight of the composition. Alternatively, ethanol may be present in an amount of from about 10 wt% or 25 wt% to about 75 wt% or 80 wt%, relative to the total weight of the composition. The ethanol useful in the present invention may be any acceptable quality of ethanol, compatible and safe for the specific intended use of the composition such as, for example, topical applications of fine fragrance or cosmetic compositions. Water

In yet another aspect, water may be present in any of the compositions of the present invention, and more specifically, it shall not exceed about 40 wt%, preferably about 20 wt% or less, or more preferably about 10 wt% or less, relative to the total weight of the composition. Alternatively, water may be present in an amount of from about 10 wt% or about 20 wt% to about 40 wt%, relative to the total weight of the composition. When the composition is a cosmetic composition the level of water should not be so high that the product becomes cloudy thus negatively impacting the product aesthetics. It is understood that the amount of water present in the composition may be from the water present in the volatile solvent (e.g., ethanol) used in the composition, as the case may be.

Non- Volatile Solvents

The composition may comprise a non-volatile solvent or a mixture of non-volatile solvents. Non-limiting examples of non- volatile solvents include benzyl benzoate, diethyl phthalate, isopropyl myristate, propylene glycol, dipropylene glycol, triethyl citrate, and mixtures thereof. These solvents often are introduced to the product via the perfume oil as many perfume raw materials may be purchased as a dilution in one of these solvents. Where nonvolatile solvents are present, introduced either with the perfume materials or separately, then for the purposes of calculating the proportion of fragrance component having a vapor pressure of less than 0.001 Torr (0.000133 kPa) at 25 °C the total fragrance components does not include non-volatile solvents. Where non-volatile solvents are present, introduced either with the perfume materials or separately, then for the purposes of calculating the total level of fragrance component this does not include non-volatile solvents. In addition if present with cyclic oligosacchrides, the non-volatile solvent may be included at a weight ratio of the non-volatile solvent to the cyclic oligosaccharide of less than 1:1, less than 1:2, less than 1:10, or less than 1:100.

Entrapment Materials

In yet another aspect, compositions of the present invention may comprise an entrapment material at a level such that the weight ratio of the entrapment material to the fragrance materials is in the range of from about 1:20 to about 20:1. Preferably, the composition may comprise an entrapment material present in the amount of from about 0.001 wt% to about 40 wt%, from about 0.1 wt% to about 25 wt%, from about 0.3 wt% to about 20 wt%, from about 0.5 wt% to about 10 wt%, or from about 0.75 wt% to about 5 wt%, relative to the total weight of the composition. The compositions disclosed herein may comprise from 0.001 wt% to 40%, from 0.1 wt% to 25 wt%, from 0.3 wt% to 20 wt%, from 0.5 wt% to 10 wt% or from 0.75 wt% to 5 wt%, relative to the total weight of the composition, of a cyclic oligosaccharide.

Suitable entrapment materials for use herein are selected from polymers; capsules, microcapsules and nanocapsules; liposomes, absorbents; cyclic oligosaccharides and mixtures thereof. Preferred are absorbents and cyclic oligosaccharides and mixtures thereof. Highly preferred are cyclic oligosaccharides (see PCT Publication Nos. WO2000/67721 (Procter & Gamble); and WO2000/67720 (Procter & Gamble); and U.S. Patent No. 6,893,647 (Procter & Gamble)).

As used herein, the term "cyclic oligosaccharide" means a cyclic structure comprising six or more saccharide units. Preferred for use herein are cyclic oligosaccharides having six, seven or eight saccharide units and mixtures thereof, more preferably six or seven saccharide units and even more preferably seven saccharide units. It is common in the art to abbreviate six, seven and eight membered cyclic oligosaccharides to α, β and γ respectively.

The cyclic oligosaccharide of the compositions used for the present invention may comprise any suitable saccharide or mixtures of saccharides. Examples of suitable saccharides include, but are not limited to, glucose, fructose, mannose, galactose, maltose and mixtures thereof. However, preferred for use herein are cyclic oligosaccharides of glucose. The preferred cyclic oligosaccharides for use herein are a-cyclodextrins or β-cyclodextrins, or mixtures thereof, and the most preferred cyclic oligosaccharides for use herein are β-cyclodextrins.

The cyclic oligosaccharide, or mixture of cyclic oligosaccharides, for use herein may be substituted by any suitable substituent or mixture of substituents. Herein the use of the term "mixture of substituents" means that two or more different suitable substituents can be substituted onto one cyclic oligosaccharide. The derivatives of cyclodextrins consist mainly of molecules wherein some of the OH groups have been substituted. Suitable substituents include, but are not limited to, alkyl groups; hydroxy alkyl groups; dihydroxyalkyl groups; (hydroxyalkyl)alkylenyl bridging groups such as cyclodextrin glycerol ethers; aryl groups; maltosyl groups; allyl groups; benzyl groups; alkanoyl groups; cationic cyclodextrins such as those containing 2-hydroxy-3-(dimethylamino) propyl ether; quaternary ammonium groups; anionic cyclodextrins such as carboxyalkyl groups, sulphobutylether groups, sulphate groups, and succinylates; amphoteric cyclodextrins; and mixtures thereof.

The substituents may be saturated or unsaturated, straight or branched chain. Preferred substituents include saturated and straight chain alkyl groups, hydroxyalkyl groups and mixtures thereof. Preferred alkyl and hydroxyalkyl substituents are selected from Ci-C ₈ alkyl or hydroxyalkyl groups or mixtures thereof, more preferred alkyl and hydroxyalkyl substituents are selected from Ci-C ₆ alkyl or hydroxyalkyl groups or mixtures thereof, even more preferred alkyl and hydroxyalkyl substituents are selected from C1-C4 alkyl or hydroxyalkyl groups and mixtures thereof. Especially preferred alkyl and hydroxyalkyl substituents are propyl, ethyl and methyl, more especially hydroxypropyl and methyl and even more preferably methyl.

Preferred cyclic oligosaccharides for use in the present invention are unsubstituted, or are substituted by only saturated straight chain alkyl, or hydroxyalkyl substituents. Therefore, preferred examples of cyclic oligosaccharides for use herein are a-cyclodextrin, β-cyclodextrin, methyl-a-cyclodextrin, methyl-P-cyclodextrin, hydroxypropyl- a-cyclodextrin and hydroxypropyl-P-cyclodextrin. Most preferred examples of cyclic oligosaccharides for use herein are methyl-a-cyclodextrin and methyl-P-cyclodextrin. These are available from Wacker-Chemie GmbH Hanns-Seidel-Platz 4, Munchen, DE under the tradename Alpha W6 M and Beta W7 M respectively. Especially preferred is methyl-P-cyclodextrin.

The cyclic oligosaccharides of the compositions used for the present invention are preferably soluble in water, ethanol, or both water and ethanol. As used herein "soluble" means at least about 0.1 g of solute dissolves in 100 mL of solvent, at 25 °C and 1 standard atmospheric pressure (760 mmHg). Preferably the cyclic oligosaccharides for use herein have a solubility of at least about 1 g/100 mL, at 25 °C and 1 atm of pressure. Preferred is that cyclic oligosaccharides are only present at levels up to their solubility limits in a given composition at room temperature. A person skilled in the art will recognise that the levels of cyclic oligosaccharides used in the present invention will also be dependent on the components of the composition and their levels, for example the solvents used or the exact fragrance oils, or combination of fragrance oils, present in the composition. Therefore, although the limits stated for the entrapment material are preferred, they are not exhaustive.

Propellants The compositions described herein may include a propellant. Some examples of propellants include compressed air, nitrogen, inert gases, carbon dioxide, and mixtures thereof. Propellants may also include gaseous hydrocarbons like propane, n-butane, isobutene, cyclopropane, and mixtures thereof. Halogenated hydrocarbons like 1,1-difluoroethane may also be used as propellants. Some non-limiting examples of propellants include 1,1,1,2,2- pentafluoroethane, 1,1,1,2-tetrafluoroethane, 1,1, 1,2,3,3, 3-heptafluoropropane, trans- 1,3,3,3- tetrafluoroprop-l-ene, dimethyl ether, dichlorodifluoromethane (propellant 12), 1,1-dichloro- 1,1,2,2-tetrafluoroethane (propellant 114), l-chloro-l,l-difluoro-2,2-trifluoroethane (propellant 115), l-chloro-l,l-difluoroethylene (propellant 142B), 1,1-difluoroethane (propellant 152A), monochlorodifluoromethane, and mixtures thereof. Some other propellants suitable for use include, but are not limited to, A-46 (a mixture of isobutane, butane and propane), A-31 (isobutane), A- 17 (n-butane), A- 108 (propane), AP70 (a mixture of propane, isobutane and n- butane), AP40 (a mixture of propane, isobutene and n-butane), AP30 (a mixture of propane, isobutane and n-butane), and 152A (1,1 diflouroethane). The propellant may have a concentration from about 15%, 25%, 30%, 32%, 34%, 35%, 36%, 38%, 40%, or 42% to about 70%, 65%, 60%, 54%, 52%, 50%, 48%, 46%, 44%, or 42% by weight of the total fill of materials stored within the container.

Antiperspirant Active

The compositions described herein may be free of, substantially free of, or may include an antiperspirant active (i.e., any substance, mixture, or other material haying antiperspirant activity). Examples of antiperspirant actives include astringent metallic salts, like the inorganic and organic salts of aluminum, zirconium and zinc, as well as mixtures thereof. Such antiperspirant actives include, for example, the aluminum and zirconium salts, such as aluminum halides, aluminum hydroxyhalides, zirconyl oxyhalides, zirconyl hydroxyhalides, and mixtures thereof.

Other Ingredients

In yet another aspect, the composition consists essentially of the recited ingredients but may contain small amounts (not more than about 10 wt%, preferably no more than 5 wt%, or preferably no more than 2 wt% thereof, relative to the total weight of the composition) of other ingredients that do not impact on the fragrance profile, particularly the evaporation rate and release of the fragrance materials. For example, a fine fragrance composition may comprise stabilizing or anti-oxidant agents, UV filters or quenchers, or colouring agents, commonly used in perfumery. There are a number of other examples of additional ingredients that are suitable for inclusion in the present compositions, particularly in compositions for cosmetic use. These include, but are not limited to, alcohol denaturants such as denatonium benzoate; UV stabilisers such as benzophenone-2; antioxidants such as tocopheryl acetate; preservatives such as phenoxyethanol, benzyl alcohol, methyl paraben, and propyl paraben; dyes; pH adjusting agents such as lactic acid, citric acid, sodium citrate, succinic acid, phosphoric acid, sodium hydroxide, and sodium carbonate; deodorants and anti-microbials such as farnesol and zinc phenolsulphonate; humectants such as glycerine; oils; skin conditioning agents such as allantoin; cooling agents such as trimethyl isopropyl butanamide and menthol; silicones; solvents such as hexylene glycol; hair-hold polymers such as those described in PCT Publication No. WO94/08557 (Procter & Gamble); salts in general, such as potassium acetate and sodium chloride and mixtures thereof.

In yet another aspect, the composition of the present invention, depending on its intended use, is a mixture of fragrance materials possibly together with other ingredients such as, for example, perfume carriers. By the term "perfume carrier", it is meant to include materials which are practically neutral from a perfumery point of view, i.e., which does not significantly alter the organoleptic properties of perfuming components. The perfume carrier may be a compatible liquid or solid fillers, diluents, and the like. The term "compatible", as used herein, means that the components of the compositions of this invention are capable of being combined with the primary actives of the present invention, and with each other, in a manner such that there is no interaction which would substantially reduce the efficacy of the composition under ordinary use situations. The type of carrier utilized in the present invention depends on the type of product desired and may comprise, but are not limited to, solutions, aerosols, emulsions (including oil-in- water or water-in-oil), gels, and liposomes. Preferably, the carrier is a liquid and will be a solvent such as, for example, dipropyleneglycol, diethyl phthalate, isopropyl myristate, benzyl benzoate, 2-(2-ethoxyethoxy)-l-ethanol, or ethyl citrate (triethyl citrate).

In yet another aspect, the compositions for use in the present invention may take any form suitable for use, more preferably for perfumery or cosmetic use. These include, but are not limited to, vapor sprays, aerosols, emulsions, lotions, liquids, creams, gels, sticks, ointments, pastes, mousses, powders, granular products, substrates, cosmetics (e.g., semi-solid or liquid makeup, including foundations) and the like. Preferably the compositions for use in the present invention take the form of a vapor spray. Compositions of the present invention can be further added as an ingredient to other compositions, preferably fine fragrance or cosmetic compositions, in which they are compatible. As such they can be used within solid composition or applied substrates etc.

Preferably, the compositions of the present invention comprise:

(i) a fragrance component present in an amount of from about 0.04 wt% to about 30 wt%, relative to the total weight of the composition, and wherein the fragrance component comprises:

(a) at least one low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C;

(b) at least one moderate volatile fragrance material having a vapor pressure from greater than or equal to 0.001 Torr to 0.1 Torr (0.000133 kPa to 0.0133 kPa) at 25 °C; and

(c) at least one high volatile fragrance material having a vapor pressure greater than 0.1 Torr (0.0133 kPa) at 25 °C;

wherein the weight ratio of (a) versus the combination of (b) and (c) are present in the range of from about 1:2.33 to about 1:9;

(ii) at least one substantially non-odorous fragrance modulator present in the amount of from about 0.1 wt% to about 20 wt%, relative to the total weight of the composition;

(iii) a volatile solvent present in an amount of from about 50 wt% to about 80 wt%, relative to the total weight of the composition; and

(iv) optionally water.

Preferably, the present invention relates to a fine fragrance composition, preferably in the form of a perfume concentrate, a perfume, a parfum, an eau de toilette, an eau de parfum, or a cologne.

Preferably, the present invention relates to a composition, wherein the composition is in the form of a body splash or a body spray.

Therefore, it goes without saying that the compositions of the present invention encompasses any composition comprising any of the ingredients cited herein, in any embodiment wherein each such ingredient is independently present in any appropriate amount as defined herein. Many such compositions, than what is specifically set out herein, can be encompassed. Article of Manufacture

The composition may be included in an article of manufacture comprising a spray dispenser. The spray dispenser may comprise a vessel for containing the composition to be dispensed. The spray dispenser may comprise an aerosolized composition (i.e., a composition comprising a propellant) within the vessel as well. Other non-limiting examples of spray dispensers include non-aerosol dispensers (e.g., vapor sprays), manually activated dispensers, pump-spray dispensers, or any other suitable spray dispenser available in the art.

Methods of Using the Compositions

The composition of the present invention according to any embodiments described herein is a useful perfuming composition, which can be advantageously used as consumer products intended to perfume any suitable substrate. As used herein, the term "substrate" means any surface to which the composition of the present invention may be applied to without causing any undue adverse effect. For example, this can include a wide range of surfaces including human or animal skin or hair, paper (fragranced paper), air in a room (air freshener or aromatherapy composition), fabric, furnishings, dishes, hard surfaces and related materials. Preferred substrates include body surfaces such as, for example, hair and skin, most preferably skin.

The composition of the present invention may be used in a conventional manner for fragrancing a substrate. An effective amount of the composition, typically from about 1 μL· to about 10,000 μΐ _^ , preferably from about 10 μΐ _^ to about 1,000 μΐ _^ , more preferably from about 25 μL· to about 500 μΐ _^ , or most preferably from about 50 μΐ _^ to about 100 μΐ _^ , or combinations thereof, is applied to the suitable substrate. Alternatively, an effective amount of the composition of the present invention is from about 1 μί, 10 μΐ _^ , 25 μΐ _^ or 50 μΐ _^ to about 100 μί, 500 μΐ _^ , 1,000 μΐ _^ or 10,000 μh. The composition may be applied by hand or applied utilizing a delivery apparatus such as, for example, vaporizer or atomizer. Preferably, the composition is allowed to dry after its application to the substrate. The scope of the present invention should be considered to cover one or more distinct applications of the composition or the continuous release of a composition via a vaporizer or other type of atomizer.

The present invention provides a method for imparting, intensifying, or modifying an odour on human skin or human hair, comprising applying to human skin and/or human hair the composition of the present invention. It is preferred that the method is for imparting, intensifying or modifying the longevity of a floral character or aromatic/spicy character on human skin or human hair, wherein the perceived intensity of the floral character or aromatic/spicy character at 1 hr, 2 hrs, 3 hrs or 6 hrs after application is greater than a control composition that does not include the substantially non-odorous fragrance modulator as determined by the panel method as disclosed herein.

Non-limiting examples of floral character is selected from the group consisting of lavender-type note, a rose-type note, a lily of the valley-type note, a muguet-type note, a jasmine-type note, a magnolia- type note, a cyclamen-type note, a hyacinth-type note, a lilac-type note, an orange blossom-type note, a cherry blossom-type note, a peony-type note, a lotus-type note, a linden blossom-type note, an osmanthus-type note, a lilac-type note, a heliotrope-type note, a violet-type note, an orris-type note, a tiare-type note, a patchouli-type note and the like.

Non-limiting examples of of aromatic (or haerbaceous) and spicy character include: cinnamon, cloves, coriander, ginger, saffron, peppers of various kinds (e.g.: black pepper, pink pepper), caraway, cardamom, anise, tea, coffee, cumin, nutmeg, coumarin, basil, rosemary, thyme, mint, tarragon, marjoram, fennel, sage, juniper and the like.

Preferably, the fragrance profile or character of the composition of the present invention is detectable by a consumer at later time points such as, for example, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 7 hours, 8 hours, 10 hours, and possibly all the way up to 24 hours after application of the composition to a substrate as compared to controls (i.e., classical fragrance pyramid three-tiered structure).

The present invention also relates to compositions of the present invention that may be used as consumer products or articles selected from the group consisting of a fabric care product, an air care product, or a home care product. Therefore, according to this embodiment, the present invention provides a method of modifying or enhancing the odour properties of a substrate, preferably fabric, furnishings, dishes, hard surfaces and related materials, comprising contacting or treating the substrate with a composition of the present invention.

In another aspect, the present invention is also directed to a method of producing a consumer product comprising bringing into contact or mixing into the product an organoleptically active quantity of a composition of the present invention.

Fragrance Materials In order that the compositions can be developed with the appropriate fragrance profile for the present invention, the "fragrance materials" have been classified as low, moderate or high volatile fragrance materials according to their volatility by their vapor pressure. This method of classifying fragrance materials by their vapor pressure avoids the problem of different classifications for the same fragrance material according to the traditional approach that relies on their subjective characteristic character. For the purpose of clarity, when the fragrance materials refer to a single individual compound, its vapor pressure should be determined according to the reference program cited above. In the case that the fragrance materials are a natural oil, extract or absolute, which comprises a mixture of several compounds, the vapor pressure of the complete oil should be treated a mixture of the individual perfume raw material components using the reference program cited above. The individual components and their level, in any given natural oil or extract, can be determined by direct injection of the oil into a GC-MS column for analysis as known by one skilled in the art. In the scenario that the fragrance materials are a proprietary specialty accord, so called 'bases', the vapor pressure, using the reference program cited above, should preferably be obtained from the supplier. However, it is understood by one skilled in the art that they can physically analyze the composition of a full fragrance oil available commercially to identity the fragrance raw materials and their levels using standard GC-MS techniques. This would be irrespective of whether they had been added to the fragrance oil as individual chemicals, as components of naturals or from proprietary bases. Although proprietary bases and naturals are included in our examples, when analyzing a commercially available fragrance via GC-MS one could simply identify the components of the base or natural oil as part of the overall fragrance mixture and their levels, without being able to identify which proprietary base or natural oil the fragrance had come from.

The nature and type of fragrance materials in the compositions according to the present invention can be selected by the skilled person, on the basis of its general knowledge together with the teachings contained herein, with reference to the intended use or application of the composition and the desired fragrance profile effect. Examples of suitable fragrance materials are disclosed in U.S. Pat. No. 4,145,184, U.S. Pat. No. 4,209,417, U.S. Pat. No. 4,515,705, and U.S. Pat. No. 4,152,272. (i) Low Volatile Fragrance Materials Preferable examples of fragrance materials having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C are provided in Table 1 Low Volatile Fragrance Materials. Preferably, the low volatile fragrance material is selected from at least 1 material, or at least 2 materials, or at least 3 materials, or at least 5 materials, or at least 7 low volatile fragrance materials as disclosed in Table 1.

Table 1 - Low Volatile Fragrance Materials

No. CAS Vapor Pressure Number IUPAC Name Common Name**

(Torr at 25°Q*

Cyclopentaneacetic acid, 3-oxo-2-

1. 1211-29- (2Z)-2-penten-l-yl-, methyl ester, Methyl jasmonate 0.00096500 6

(1R,2R>

2. 28219- 2-Buten-l-ol, 2-methyl-4-(2,2,3-

Hindinol 0.00096100 60-5 trimethyl-3-cyclopenten- 1-yl)-

3. Methyl beta-naphthyl

93-08-3 Ethanone, l-(2-naphthalenyl)- 0.00095700 ketone

4. 67633- Methyl Lavender

3-Decanone, 1-hydroxy- 0.00095100 95-8 Ketone

5. Cyclopropanemethanol, 1-methyl-

198404- 2- [( 1 ,2,2-trimethylbicyclo [3.1.0] Javanol ^® 0.00090200 98-7

hex-3-yl)methyl]-

6. Benzaldehyde, 3-ethoxy-4-

121-32-4 Ethyl vanillin 0.00088400 hydroxy-

7. 72403- 3 -Cyclohexene-1 -methanol, 4-(4-

Myraldylacetate 0.00087900 67-9 methyl-3-penten- 1-yl)-, 1-acetate

8. 28940- 2H- 1 , 5 -B enzodioxepin- 3 (4H) -one,

Oxalone ^® 0.00083100 11-6 7-methyl-

9. 139504- 2-Butanol, l-[[2-(l,l-

Amber core 0.00080300

68-0 dimethylethyl)cyclohexyl] oxy] -

10. Spiro[5.5]undec-8-en-

502847- Spiro[5.5]undec-8-en-l-one, 2,2,7,

1-one, 2,2,7,9- 0.00073100 01-0 9-tetramethyl- tetramethyl-

11. 2570-03- Cyclopentaneacetic acid, 3-oxo-2- trans-Hedione 0.00071000 8 pentyl-, methyl ester, (lR,2R)-rel-

12. Methyl

24851- Cyclopentaneacetic acid, 3-oxo-2- dihydrojasmonate or 0.00071000 98-7 pentyl-, methyl ester

alternatives ^;

13. Hexyl cinnamic

101-86-0 Octanal, 2-(phenylmethylene)- 0.00069700 aldehyde Indeno[4,5-d]-l,3-dioxin, 4,4a,5,6,

365411- 7,8,9,9b-octahydro-7,7,8,9,9- Nebulone 0.00069200 50-3

pentamethyl-

37172- Cyclopentanecarboxylic acid, 2-

Dihydro Iso Jasmonate 0.00067500 53-5 hexyl-3-οχο-, methyl ester

65113- 3 -Cyclopentene- 1 -butanol, α,β ,2,2,

Sandalore ^® 0.00062500 99-7 3-pentamethyl-

68133- Cyclopentanone, 2-(3,7-dimethyl-

Apritone 0.00062000 79-9 2,6-octadien-l-yl)-

7212-44- l,6,10-Dodecatrien-3-ol, 3,7,11-

Nerolidol 0.00061600 4 trimethyl-

53243- 2-Pentenenitrile, 3-methyl-5-

Citronitril 0.00061500 59-7 phenyl-, (2Z)-

134123- Benzenepropanenitrile, 4-ethyl-a,

Fleuranil 0.00057600 93-6 a-dimethyl- lH-3a,7-Methanoazulen-6-ol,

77-53-2 octahydro- 3 ,6 , 8 , 8 - tetramethyl- , Cedrol Crude 0.00056900

(3R,3aS,6R R S)-

Ethanone, l-(l,2,3,5,6,7,8,8a-

68155- octahydro-2,3,8,8-tetramethyl-2- Iso Gamma Super 0.00056500 66-8

naphthalenyl)-

Ethanone, 1-(1,2,3,4,5,6,7,8-

54464- octahydro-2,3,8,8-tetramethyl-2- Iso-E Super ^® 0.00053800 57-2

naphthalenyl)-

Ethanone, l-(5,6,7,8-tetrahydro-2-

774-55-0 Florantone 0.00053000 naphthalenyl)-

2-Octanol, 8,8-dimethoxy-2,6- Hydroxycitronellal

141-92-4 0.00052000 dimethyl- Dimethyl Acetal

20665- Propanoic acid, 2-methyl-, 4-

Vanillin isobutyrate 0.00051200 85-4 formyl-2-methoxyphenyl ester

l,6-Heptadien-3-one, l-(2,6,6-

79-78-7 Hexalon 0.00049800 trimethyl-2-cyclohexen- 1-yl)-

6259-76- Benzoic acid, 2-hydroxy-, hexyl

Hexyl Salicylate 0.00049100 3 ester

93-99-2 Benzoic acid, phenyl ester Phenyl Benzoate 0.00047900

153859- Cyclohexanepropanol, 2,2,6-

Norlimbanol 0.00046900 23-5 trimethyl-a-propyl-, (IR,6S)-

70788- Cyclohexanepropanol, 2,2,6-

Timberol 0.00046900 30-6 trimethyl- a-propyl-

68555- Benzoic acid, 2-hydroxy-, 3-

Prenyl Salicylate 0.00045700 58-8 methyl-2-buten-l-yl ester

950919- 2H- 1 , 5 -B enzodioxepin- 3 (4H) -one,

Cascalone 0.00045500 28-5 7-(l-methylethyl)-

9-29-5 Oxacycloheptadecan-2-one Silvanone Ci 0.00002600

Benzeneacetic acid, 4- Para Cresyl Phenyl

1-94-0 0.00002330 methylphenyl ester Acetate

Benzeneacetic acid, 2-phenylethyl Phenyl Ethyl Phenyl

2-20-5 0.00002300 ester Acetate

8562-

Cyclododecaneethanol, β-methyl- Hydroxyambran 0.00001800-5

2-Propenoic acid, 3 -phenyl-,

3-41-3 Benzyl Cinnamate 0.00001050 phenylmethyl ester 07-47- Benzoic acid, 2,4-dihydroxy-3,6-

Veramoss 0.00001050 dimethyl-, methyl ester

3551- Naphtho[2, l-b]furan-6(7H)-one,

Myrrhone 0.00000977-9 8,9-dihydro-l,5,8-trimethyl-, (8R)-

Benzeneacetic acid, (4- Para Anisyl Phenyl

2-17-0 0.00000813 methoxyphenyl)methyl ester Acetate

Benzene, 2-methoxy-l-0-11-6 (phenylmethoxy)-4-(l-propen- 1- Benzyl Iso Eugenol 0.00000676 yl)-

Benzeneacetic acid, (2E)-3,7-2-22-7 Geranyl Phenylacetate 0.00000645 dimethyl-2,6-octadien-l-yl ester 1879- Oxacyclohexadec- 12-en-2-one,

Habanolide 100% 0.00000431-2 (12E)-

Benzoic acid, 2-hydroxy-, 2- Phenyl Ethyl

-22-9 0.00000299 phenylethyl ester Salicylate

2-Propenoic acid, 3 -phenyl-, 1--37-5 ethenyl- 1 ,5-dimethyl-4-hexen- 1 -yl Linalyl Cinnamate 0.00000174 ester

645-

Oxacycloheptadec- 10-en-2-one Ambrettolide 0.00000139-4

Oxacycloheptadec-8-en-2-one,

3-69-3 Ambrettolide 0.00000136 (8Z)-91-83- l,7-Dioxacycloheptadecan-8-one Musk RI 0.00000057 527- 7-Octen-2-ol, 8-(lH-indol-l-yl)-

Indolene 0.000000445-7 2,6-dimethyl- 107. Methyl 2-[(7-hydroxy-3,7-

89-43-0 dimethyloctylidene)amino]benzoat Aurantinol 0.0000000100 e

108. 54982- 1 ,4-Dioxacyclohexadecane-5 , 16-

Zenolide 0.00000000834 83-1 dione

109. l,4-Dioxacycloheptadecane-5,17-

105-95-3 Ethylene Brassylate 0.00000000313 dione

110. 3681-73- Hexadecanoic acid, (2E)-3,7-

Hexarose 0.00000000300 0 dimethyl-2,6-octadien-l-yl ester

111. 4159-29- Phenol, 4-[3-(benzoyloxy)-l-

Coniferyl benzoate 0.00000000170 9 propen- 1 -yl] -2-methoxy-

112. 144761- Benzoic acid, 2-[(l-hydroxy-3-

Trifone DIPG 0.00000000093 91-1 phenylbutyl)amino]-, methyl ester

Non-limiting examples of alternative qualities from various suppliers can be purchased under the following tradenames: Kharismal ^® Super (IFF), Kharismal ^® (IFF), Hedione ^® (Firmenich), Hedione ^® HC (Firmenich), Paradisone (Firmenich), Cepionate (Zenon), Super cepionate (Zenon), Claigeon ^® (Zenon).

* Vapor Pressures are acquired as described in the Test Methods Section.

** Origin: The low volatile fragrance materials may be obtained from one or more of the following companies: Firmenich (Geneva, Switzerland), Symrise AG (Holzminden, Germany), Givaudan (Argenteuil, France), IFF (Hazlet, New Jersey), Bedoukian (Danbury, Connecticut), Sigma Aldrich (St. Louis, Missouri), Millennium Speciality Chemicals (Olympia Fields, Illinois), Polarone International (Jersey City, New Jersey), and Aroma & Flavor Specialities (Danbury, Connecticut).

Exemplary low volatile fragrance materials selected from the group of Table 1 Low Volatile Fragrance Materials are preferred. However, it is understood by one skilled in the art that other low volatile fragrance materials, not recited in Table 1, would also fall within the scope of the present invention, so long as they have a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C.

Preferably, the compositions of the present invention, wherein: (i)(a) the low volatile fragrance material is selected from the group of Table 1 Low Volatile Fragrance Materials 1, 4-6, 8, 12-16, 18, 22-25, 27-28, 31, 34-37, 41, 45, 47, 52-55, 57, 60, 61, 63, 65, 68, 69-74, 75, 78, 80, 83-84, 89, 94, 99, 102, 104, 106-108, and mixtures thereof; and (ii) the substantially non-odorous fragrance modulator is selected from the group of Table 4(a) Substantially Non-Odorous Fragrance Modulators 1-5, and mixtures thereof.

Preferably, the compositions of the present invention, wherein: (i)(a) the low volatile fragrance material is selected from the group consisting of Table 1 Low Volatile Fragrance Materials 1-6, 8-9, 12-14, 16, 18-19, 23, 25-28, 31, 34-35, 37, 41-42, 45, 47-49, 53-55, 57-60, 63, 65, 69, 71-73, 75, 78-79, 81, 84-85, 95, 100, 103, 105, 107, 109 and mixtures thereof; and (ii) the substantially non-odorous fragrance modulator is selected from the group of Table 4(a) Substantially Non-Odorous Fragrance Modulators 6-8, and mixtures thereof.

Preferably, the compositions of the present invention, the low volatile fragrance material is selected from the group (as described herein above), and wherein this group of low volatile fragrance material has at least about 20 wt%, at least about 30 wt%, at least about 40 wt%, at least about 50 wt%, at least about 60 wt%, or at least about 70 wt%, relative to the total weight of the low volatile fragrance material.

(ii) Moderate Volatile Fragrance Materials Preferable examples of moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C are provided in Table 2 Moderate Volatile Fragrance Materials. Preferably, the moderate volatile fragrance material is selected from at least 1 material, or at least 2 materials, or at least 3 materials, or at least 5 materials, or at least 7 moderate volatile fragrance materials as disclosed in Table 2. Table 2 - Moderate Volatile Fragrance Materials

No. CAS Vapor Pressure Number IUPAC Name Common Name**

(Torr at 25 °Q*

1. Pyrazine, 2-methoxy-3-(l-

24168-70-5 Methoxyisobutylpyrazine 0.09950000 methylpropyl)-

2. Cyclohexanol, 5-methyl-2-

89-79-2 (1-methylethenyl)-, (IR, Iso-Pulegol 0.09930000

2S,5R>

3. 112-12-9 2-Undecanone Methyl Nonyl Ketone 0.09780000

4. Benzenepropanol, α,α- Phenyl Ethyl Dimethyl

103-05-9 0.09770000 dimethyl- Carbinol

5. Bicyclo[2.2. l]heptan-2-ol,

125-12-2 Iso Bornyl Acetate 0.09590000

1,7,7-trimethyl-, 2-acetate, (lR,2R,4R)-rel- l,6-Octadien-3-ol, 3,7-

78-70-6 Linalool 0.09050000 dimethyl-

Benzeneacetic acid, ethyl

101-97-3 Ethyl Phenyl Acetate 0.08970000 ester

Benzeneethanol, α,α-

100-86-7 Dimethyl Benzyl Carbinol 0.08880000 dimethyl-

Cyclopropanecarboxylic

188570-78- acid, (3Z)-3-hexen-l-yl Montaverdi 0.08640000 7

ester

3 -Cyclohexene- 1 -

67634-25-7 methanol, 3,5-dimethyl-, Floralate 0.08500000

1 -acetate

112-44-7 Undecanal Undecyl Aldehyde 0.08320000

Ethanone, l-(3-

32669-00-4 Tanaisone ^® 0.08150000 cycloocten-l-yl)-

Cyclohexanone, 4-(l,l-

98-53-3 Patchi 0.07780000 dimethylethyl)-

35854-86-5 6-Nonen-l-ol, (6Z)- cis-6-None-l-ol 0.07770000

5331-14-6 Benzene, (2-butoxyethyl)- Butyl phenethyl ether 0.07760000

Bicyclo[3.1. l]hept-3-en-2-

80-57-9 Verbenone 0.07730000 one, 4,6,6-trimethyl-

Cyclohexanecarboxylic

22471-55-2 acid, 2,2,6-trimethyl-, Thesaron 0.07670000 ethyl ester, (lR,65)-rel-

60-12-8 Benzeneethanol Phenethyl alcohol 0.07410000

2,6-Octadienal, 3,7-

106-26-3 Neral 0.07120000 dimethyl-, (2Z)-

2,6-Octadienal, 3,7-

5392-40-5 Citral 0.07120000 dimethyl-

Cyclohexanol, 5-methyl-2-

89-48-5 (1-methylethyl)-, 1- Menthyl Acetate 0.07070000 acetate, (lR,25,5R)-rel-

Benzoic acid, 2-hydroxy-,

119-36-8 Methyl salicylate 0.07000000 methyl ester

Benzene, l-methoxy-4-

4180-23-8 Anethol 0.06870000

(lE)-l-propen-l-yl-

2,6-Octadiene, 1,1-

7549-37-3 Citral Dimethyl Acetal 0.06780000 dimethoxy-3 ,7-dimethyl-

Cyclohexanemethanol, a,

25225-08-5 Aphermate 0.06780000

3,3-trimethyl-, 1 -formate

3913-81-3 2-Decenal, (2E)- 2-Decene-l-al 0.06740000 3 -Cyclopentene- 1 -

15373-31-6 acetonitrile, 2,2,3- Cantryl ^® 0.06700000 trimethyl-

2-Cyclohexen-l-one, 2-

6485-40-1 methyl-5-(l- Laevo carvone 0.06560000 methylethenyl)-, (5R)-

Cyclohexanone, 4-(l,l-

16587-71-6 Orivone 0.06490000 dimethylpropyl)-

6,10-

Dioxaspiro [4.5] decane,

62406-73-9 Opalal CI 0.06290000

8,8-dimethyl-7-(l- methylethyl)-

2-Cyclohexen-l-one, 3-

3720-16-9 Livescone 0.06270000 methyl- 5 -propyl-

Benzonitrile, 4-(l-

13816-33-6 Cumin Nitrile 0.06230000 methylethyl)-

67019-89-0 2,6-Nonadienenitrile Violet Nitrile 0.06200000

Butanoic acid, 2-methyl-, cis-3-Hexenyl Alpha

53398-85-9 0.06130000

(3Z)-3-hexen-l-yl ester Methyl Butyrate

208041-98- n/a Jasmonitrile 0.05920000 9

Benzene, 1-

16510-27-3 (cyclopropylmethyl)-4- Toscanol 0.05870000 methoxy-

2-Nonynoic acid, methyl

111-80-8 Methyl Octine Carbonate 0.05680000 ester

Acetic acid, 2-phenylethyl

103-45-7 Phenyl Ethyl Acetate 0.05640000 ester

2550-26-7 2-Butanone, 4-phenyl- Benzyl Acetone 0.05570000

Cyclohexanol, 2-(l,l-

13491-79-7 Verdol 0.05430000 dimethylethyl)-

7786-44-9 2,6-Nonadien- 1 -ol 2,6-Nonadien- 1 -ol 0.05370000

Propanoic acid, 2-methyl-,

103-28-6 Benzyl Iso Butyrate 0.05130000 phenylmethyl ester

Formic acid, 2-phenylethyl

104-62-1 Phenyl Ethyl Formate 0.05050000 ester

Bicyclo[2.2. l]heptan-2-ol,

28462-85-3 1,2,3,3-tetramethyl-, (IR, Humus Ether 0.04870000

2tf,4S)-rel-

Benzaldehyde, 4-(l-

122-03-2 Cuminic Aldehyde 0.04820000 methylethyl)-

358331-95- 2,5-Octadien-4-one, 5,6,7-

Pomarose 0.04810000 0 trimethyl-, (2E)- 2,4-Cyclohexadiene- 1 -

35044-57-6 carboxylic acid, 2,6,6- Ethyl Safranate 0.03880000 trimethyl-, ethyl ester

106-21-8 1-Octanol, 3,7-dimethyl- Dimethyl Octanol 0.03860000

84560-00-9 Cyclopentanol, 2-pentyl- Cyclopentol 0.03790000

Furan, tetrahydro-2,4-

82461-14-1 Rhubafuran ^® 0.03780000 dimethyl-4-phenyl-

Benzene, [2-(3- Phenyl Ethyl Isoamyl

56011-02-0 0.03690000 methylbutoxy)ethyl] - Ether

Butanoic acid,

103-37-7 Benzyl Butyrate 0.03660000 phenylmethyl ester

6378-65-0 Hexyl hexanoate Hexyl hexanoate 0.03490000

Benzoic acid, 2-hydroxy-,

118-61-6 Ethyl salicylate 0.03480000 ethyl ester

Cyclohexanol, 4-(l,l-

98-52-2 Patchon 0.03480000 dimethylethyl)- l,6-Octadien-3-ol, 3,7-

115-99-1 Linalyl Formate 0.03440000 dimethyl-, 3 -formate

112-54-9 Dodecanal Laurie Aldehyde 0.03440000

3,6-Nonadien-l-ol, (3Z,

53046-97-2 3,6 Nonadien-l-ol 0.03360000

6Z)-

76649-25-7 3 ,6-Nonadien- 1 -ol 3 ,6-Nonadien- 1 -ol 0.03360000

141-25-3 3 ,7-Dimethyloct-6-en- 1 -ol Rhodinol 0.03290000

1975-78-6 Decanenitrile Decanonitrile 0.03250000

Cyclohexanol, 5-methyl-2-

2216-51-5 (1-methylethyl)-, (1R.25, L-Menthol 0.03230000

5R)-

4-hydroxy-2,5-

3658-77-3 Pineapple Ketone 0.03200000 dimethylfuran-3 -one

Propanoic acid, 2-methyl-,

103-93-5 Para Cresyl iso-Butyrate 0.03120000

4-methylphenyl ester

Propanoic acid, 2-methyl-,

( 1R,25,4R)- 1,7,7-

24717-86-0 Abierate 0.03110000 trimethylbicyclo[2.2.1]

hept-2-yl ester, rel-

Acetaldehyde, 2-(4-

67845-46-9 Aldehyde XI 0.03090000 methylphenoxy ) -

2-Butenoic acid, 2-methyl-

67883-79-8 , (3Z)-3-hexen-l-yl ester, Cis-3-Hexenyl Tiglate 0.03060000

(2E)- Bicyclo[3.1. l]hept-2-ene-

33885-51-7 Pino Acetaldehyde 0.03040000

2-propanal, 6,6-dimethyl-

6-Octen-l-ol, 3,7-

105-85-1 Citronellyl Formate 0.03000000 dimethyl-, 1 -formate

70214-77-6 2-Nonanol, 6,8-dimethyl- Nonadyl 0.03010000

215231-33- Cyclohexanol, l-methyl-3-

Rossitol 0.02990000 7 (2-methylpropyl)-

120-72-9 lH-Indole Indole 0.02980000

2463-77-6 2-Undecenal 2-Undecene-l-al 0.02970000

2H-Pyran-2-one, 4,6-

675-09-2 Levistamel 0.02940000 dimethyl-

3 -Cyclohexene- 1 -

98-55-5 Alpha-Terpineol 0.02830000 methanol, a,a,4-trimethyl-

3-Hepten-2-one, 3,4,5,6,6-

81786-73-4 Koavone 0.02750000 pentamethyl-, (3Z)-

122-97-4 Benzenepropanol Phenyl Propyl Alcohol 0.02710000

2(3H)-Furanone, 5-

39212-23-2 Methyl Octalactone 0.02700000 butyldihydro-4-methyl-

7-Octen-2-ol, 2,6-

53767-93-4 Dihydro Terpinyl Acetate 0.02690000 dimethyl-, 2- acetate

1 ,3 -Cyclohexadiene- 1 -

35044-59-8 carboxylic acid, 2,6,6- Ethyl Safranate 0.02660000 trimethyl-, ethyl ester

104-55-2 2-Propenal, 3 -phenyl - Cinnamic Aldehyde 0.02650000 l,6-Octadien-3-ol, 3,7-

144-39-8 Linalyl Propionate 0.02630000 dimethyl-, 3-propanoate

l,6-Nonadien-3-ol, 3,7- 3,7-Dimethyl-l,6-

61931-80-4 0.02630000 dimethyl-, 3 -acetate nonadien-3-yl acetate

Benzeneacetic acid, 2-

102-13-6 Iso Butyl Phenylacetate 0.02630000 methylpropyl ester

Cyclopentanone, 2,2,5-

65443-14-3 Veloutone 0.02610000 trimethyl- 5 -pentyl-

2,6-Octadien-l-ol, 3,7-

141-12-8 Neryl Acetate 0.02560000 dimethyl-, 1-acetate, {27)-

2,6-Octadien-l-ol, 3,7-

105-87-3 Geranyl acetate 0.02560000 dimethyl-, 1-acetate, (2E)-

Methyl Nonyl

Undecane, 1,1-dimethoxy-

68141-17-3 Acetaldehyde Dimethyl 0.02550000

2-methyl- Acetal

Benzenemethanol, a-

2206-94-2 Indocolore 0.02550000 methylene-, 1-acetate Cyclohexanepropanol, a-

10528-67-3 Cyclohexylmagnol 0.02550000 methyl-

123-11-5 Benzaldehyde, 4-methoxy- Anisic Aldehyde 0.02490000

Cyclohexanol, 5-methyl-2-

57576-09-7 (1-methylethenyl)-, 1- Iso Pulegol Acetate 0.02480000 acetate, (1R,2S,5R)-

6-Octenenitrile, 3,7-

51566-62-2 Citronellyl Nitrile 0.02470000 dimethyl-

2H-Pyran, 3,6-dihydro-4-

60335-71-9 Rosyrane Super 0.02470000 methyl-2-phenyl-

6-Octen-2-ol, 2,6-

30385-25-2 Dihydromyrcenol 0.02440000 dimethyl-

101-84-8 Benzene, Ι,Γ-oxybis- Diphenyl Oxide 0.02230000

136-60-7 Benzoic acid, butyl ester Butyl Benzoate 0.02170000

5,8-Methano-2H-l-

93939-86-7 benzopyran, 6- Rhuboflor 0.02120000 ethylideneoctahydro -

Cyclohexanepropanol, α,α-

83926-73-2 Coranol 0.02100000 dimethyl-

125109-85- Benzenepropanal, β-

Florhydral 0.02070000 5 methyl- 3 - ( 1 -methylethyl) -

Benzenemethanol, 4-

104-21-2 Anisyl Acetate 0.02050000 methoxy-, 1 -acetate

2-Furanmethanol, 5-

1365-19-1 ethenyltetrahydro- a, a,5 - Linalool Oxide 0.02050000 trimethyl-

137-03-1 Cyclopentanone, 2-heptyl- Frutalone 0.02040000

Phenol, 2-ethoxy-4-

2563-07-7 Ultravanil 0.02030000 methyl-

2-Cyclopenten-l-one, 3-

1128-08-1 Dihydroj asmone 0.02020000 methyl-2-pentyl-

Benzene, [2-(l-

7493-57-4 Acetaldehyde 0.01990000 propoxyethoxy)ethyl] -

7-Octen-l-ol, 3,7-

141-25-3 Rhodinol 0.01970000 dimethyl-

Bicyclo[4.3.1]decane, 3- 3-Methoxy-7,7-dimethyl-

216970- methoxy-7,7-dimethyl- 10- 10-methylenebicyclo [4.3 0.01960000 21-7

methylene- .l]decane

Propanoic acid, 2-(l,l-

319002-92- dimethylpropoxy)-, propyl Sclareolate ^® 0.01960000 1

ester, (25)-

Benzoic acid, 2-

85-91-6 Dimethyl anthranilate 0.01930000

(methylamino)-, methyl

, a met anonap t aene ,

-p enyet y ester Heptanal, 2-

122-40-7 Amyl Cinnamic Aldehyde 0.00233000

(phenylmethylene) -

103694-68- Benzenepropanol, β,β,3-

Majantol ^® 0.00224000 4 trimethyl-

2-Cyclohexen-l-one, 4-(2-

13215-88-8 buten-l-ylidene)-3,5,5- Tabanone Coeur 0.00223000 trimethyl-

3-Hexen-l-ol, 1-benzoate,

25152-85-6 Cis-3-Hexenyl Benzoate 0.00203000

(3Z)-

406488-30- 2-Ethyl-N-methyl-N-(m-

Paradisamide 0.00200000 0 tolyl)butanamide

Benzaldehyde, 4-hydroxy-

121-33-5 Vanillin 0.00194000

3-methoxy- lH-3a,7-Methanoazulen-

6-ol, octahydro-3,6,8,8-

77-54-3 Cedac 0.00192000 tetramethyl-, 6-acetate,

(3tf,3aS,6tf,7tf,8aS)-

4,7-Methano- lH-inden-6- ol, 3a,4, 5,6,7,7a-

76842-49-4 Frutene 0.00184000 hexahydro- 8 , 8-dimethyl- ,

6-propanoate

2- Oxiranecarboxylic acid,

121-39-1 Ethyl Phenyl Glycidate 0.00184000

3 - phenyl-, ethyl ester

4H-4a,9-

Methanoazuleno [5 ,6-d] - 1 ,

211299-54- 3-dioxole, octahydro-2,2, Ambrocenide ^® 0.00182000 6

5,8, 8 ,9a-hexamethyl- ,

(4aR,5R,7aS,9R)-

(2,5-Dimethyl-l,3-

285977-85- dihydroinden-2- Lilyflore 0.00180000 7

yl)methanol

Butanoic acid, 1,1-

Dimethyl Benzyl Carbinyl

10094-34-5 dimethyl-2-phenylethyl 0.00168000

Butyrate

ester

Cyclododeca[c]furan, 1,3,

40785-62-4 3a,4,5,6,7,8,9,10,l 1,13a- Muscogene 0.00163000 dodecahydro-

Benzenebutanenitrile, a, a,

75490-39-0 Khusinil 0.00162000 γ-trimethyl-

2-Butanone, 4-(l,3-

55418-52-5 Dulcinyl 0.00161000 benzodioxol- 5 -yl) -

Benzoic acid, 4-hydroxy-

3943-74-6 Carnaline 0.00157000

3-methoxy-, methyl ester

3 -Cyclopentene- 1 -butanol,

72089-08-8 P,2,2,3-tetramethyl- Brahmanol ^® 0.00154000

2-Methyl-4-(2,2,3-

Vapor Pressures are acquired as described in the Test Methods Section.

** Origin: Same as for Table 1 hereinabove.

Exemplary moderate volatile fragrance materials selected from the group of Table 2 Moderate Volatile Fragrance Materials are preferred. However, it is understood by one skilled in the art that other moderate volatile fragrance materials, not recited in Table 2, would also fall within the scope of the present invention, so long as they have a vapor pressure of 0.1 to 0.001 Torr at 25 °C.

Preferably, the compositions of the present invention, wherein: (i)(b) the moderate volatile fragrance material is selected from the group of Table 2 Moderate Volatile Fragrance Materials 1-9, 11-12, 14-15, 17-18, 20-25, 27-35, 37-38, 39-43, 45-46, 48-53, 55-61, 63, 65, 67- 71, 73-77, 79, 81-84, 86-91, 93-122, 124-125, 130-131, 133-135, 137, 139-145, 147-149, 151, 153-155, 157, 161-162, 164-169, 171-191, 193, 195-198, 200-203, 205-215, 218-219, 221, 223- 241, 243, 245-250, 252-255, 257-262, 264-265, 267-268, 272, 273-276, 279-300, 302-304, 306, 308-310, 312-319, and mixtures thereof, and (ii) the substantially non-odorous fragrance modulator is selected from the group of Table 4(a) Substantially Non-Odorous Fragrance Modulators 1-5, and mixtures thereof.

Preferably, the compositions of the present invention, wherein: (i)(a) the moderate volatile fragrance material is selected from the group consisting of Table 2 Moderate Volatile Fragrance Materials 1, 3, 4, 6, 7, 9, 11-12, 14, 15, 17-18, 20-25, 30-31, 34-35, 37-38, 41-42, 45- 46, 49, 51-53, 55, 57-59, 65-70, 73, 75-77, 79-80, 82, 86-89, 91-94, 98, 101-107, 111-113, 115- 122, 124-125, 130-133, 135, 137, 139-143, 145, 147-149, 151, 153-155, 157-159, 161-162, 164- 168, 171-180, 182-183, 187-191, 193, 195-198, 200-203, 205-213, 218-219, 221-222, 224-229, 231-241, 243, 245-250, 252, 253, 254-255, 257-263, 264-265, 267-269, 271, 273-276, 279-300, 302-304, 306, 308-310, 312, 314-319, and mixtures thereof; and (ii) the substantially non- odorous fragrance modulator is selected from the group of Table 4(a) Substantially Non-Odorous Fragrance Modulators 6-8, and mixtures thereof.

Preferably, the compositions of the present invention, the low volatile fragrance material is selected from the group (as described herein above), and wherein this group of low volatile fragrance material has at least about 20 wt%, at least about 30 wt%, at least about 40 wt%, at least about 50 wt%, at least about 60 wt%, or at least about 70 wt%, relative to the total weight of the low volatile fragrance material.

(iii) High Volatile Fragrance Materials

Preferable examples of high volatile fragrance materials having a vapor pressure greater than 0.1 (0.0133 kPa) Torr at 25 °C are provided in Table 3 High Volatile Fragrance Materials. Preferably, the high volatile fragrance material is selected from at least 1 material, or at least 2 materials, or at least 3 materials, or at least 5 materials, or at least 7 high volatile fragrance materials as disclosed in Table 3.

Table 3 - High Volatile Fragrance Materials

No. CAS Vapor Pressure Number IUPAC Name Common Name**

(Torr at 25 °Q* 107-31-3 Formic acid, methyl ester Methyl Formate 732.00000000

Dimethyl Sulfide 1.0% In

75-18-3 Methane, Ι,Γ-thiobis- 647.00000000

DEP

141-78-6 Acetic acid ethyl ester Ethyl Acetate 112.00000000

105-37-3 Propanoic acid, ethyl ester Ethyl Propionate 44.50000000

Acetic acid, 2-

110-19-0 Isobutyl Acetate 18.00000000 methylpropyl ester

105-54-4 Butanoic acid, ethyl ester Ethyl Butyrate 13.90000000

14765-30-1 1-Butanol Butyl Alcohol 8.52000000

Butanoic acid, 2-methyl-,

7452-79-1 Ethyl-2-Methyl Butyrate 7.85000000 ethyl ester

1-Butanol, 3-methyl-, 1-

123-92-2 Iso Amyl Acetate 5.68000000 acetate

Butanoic acid, 2-methyl-, Iso Propyl 2-

66576-71-4 5.10000000

1-methylethyl ester Methylbutyrate

110-43-0 2-Heptanone Methyl Amyl Ketone 4.73000000

6728-26-3 2-Hexenal, (2E)- Trans-2 Hexenal 4.62000000

123-51-3 1-Butanol, 3-methyl- Isoamyl Alcohol 4.16000000

2-Buten-l-ol, 3-methyl-,

1191-16-8 Prenyl acetate 3.99000000

1 -acetate

l,3-Dioxolane-2-

57366-77-5 Methyl Dioxolan 3.88000000 methanamine, N-methyl-

Bicyclo[3.1. l]hept-2-ene,

7785-70-8 Alpha Pinene 3.49000000

2,6,6-trimethyl-, (1R.5R)-

Bicyclo[2.2.1]heptane, 2,

79-92-5 Camphene 3.38000000

2-dimethyl- 3 -methylene-

2-Butanethiol, 4-methoxy- 4-Methoxy-2-Methyl-2-

3.31000000

94087-83-9 2-methyl- Butanenthiol

Pentanoic acid, 2-methyl-,

39255-32-8 Manzanate 2.91000000 ethyl ester

Bicyclo[3.1.0]hexane, 4-

3387-41-5 methylene-l-(l- Sabinene 2.63000000 methylethyl)-

Bicyclo[3.1.1]heptane, 6,

127-91-3 Beta Pinene 2.40000000

6-dimethyl-2-methylene-

1-Butanol, 3-methyl-, 1-

105-68-0 Amyl Propionate 2.36000000 propanoate

1,6-Octadiene, 7-methyl-

123-35-3 Myrcene 2.29000000

3-methylene- 124-13-0 Octanal Octyl Aldehyde 2.07000000

2H-Pyran, 2-

7392-19-0 ethenyltetrahydro-2,6,6- Limetol 1.90000000 trimethyl-

111-13-7 2-Octanone Methyl Hexyl Ketone 1.72000000

123-66-0 Hexanoic acid, ethyl ester Ethyl Caproate 1.66000000

2-Oxabicyclo[2.2.2]

470-82-6 Eucalyptol 1.65000000 octane, 1,3,3-trimethyl-

Benzene, l-methyl-4-(l-

99-87-6 Para Cymene 1.65000000 methylethyl)-

Benzene, l-methoxy-4-

104-93-8 Para Cresyl Methyl Ether 1.65000000 methyl-

1,3,6-Octatriene, 3,7-

13877-91-3 Ocimene 1.56000000 dimethyl-

Cyclohexene, l-methyl-4-

138-86-3 dl-Limonene 1.54000000

( 1 -methylethenyl)-

Cyclohexene, l-methyl-4-

5989-27-5 d-limonene 1.54000000

(1-methylethenyl)-, (4R)-

106-68-3 3-Octanone Ethyl Amyl Ketone 1.50000000

Methyl Nonyl

110-41-8 Undecanal, 2-methyl- 1.43000000

Acetaldehyde

142-92-7 Acetic acid, hexyl ester Hexyl acetate 1.39000000

110-93-0 5-Hepten-2-one, 6-methyl- Methyl Heptenone 1.28000000

81925-81-7 2-Hepten-4-one, 5-methyl- Filbertone 1% in TEC 1.25000000

3-Hexen-l-ol, 1-acetate,

3681-71-8 cis-3-Hexenyl acetate 1.22000000

(3Z)-

Propanoic acid, 2-

97-64-3 Ethyl Lactate 1.16000000 hydroxy-, ethyl ester

Cyclohexene, l-methyl-4-

586-62-9 Terpineolene 1.13000000

( 1 -methylethylidene)-

Butanoic acid, 2-

51115-64-1 Amyl butyrate 1.09000000 methylbutyl ester

Butanoic acid, 3-

106-27-4 Amyl Butyrate 1.09000000 methylbutyl ester

1,4-Cyclohexadiene, 1-

99-85-4 Gamma Terpinene 1.08000000 methyl-4-( 1 -methylethyl)-

Thiazole, 2-(2-

18640-74-9 2-Isobutylthiazole 1.07000000 methylpropyl)-

928-96-1 3-Hexen-l-ol, (3Z)- cis-3-Hexenol 1.04000000

met ypropy ester Propanoic acid, 2-methyl-,

2349-07-7 Hexyl isobutyrate 0.41300000 hexyl ester

Cyclohexanecarboxylic

23250-42-2 acid, 1,4-dimethyl-, Cyprissate 0.40500000 methyl ester, trans-

122-78-1 Benzeneacetaldehyde Phenyl acetaldehyde 0.36800000

Butanoic acid, 3-hydroxy-,

5405-41-4 Ethyl-3 -Hydroxy Butyrate 0.36200000 ethyl ester

Propanedioic acid, 1,3-

105-53-3 Diethyl Malonate 0.34400000 diethyl ester

93-58-3 Benzoic acid, methyl ester Methyl Benzoate 0.34000000

16356-11-9 1,3,5-Undec atriene Undecatriene 0.33600000

65405-70-1 4-Decenal, (4E)- Decenal (Trans-4) 0.33100000

1,3-Dioxane, 2-butyl-4,4,

54546-26-8 Herboxane 0.33000000

6-trimethyl-

13254-34-7 2-Heptanol, 2,6-dimethyl- Dimethyl-2 6-Heptan-2-ol 0.33000000

98-86-2 Ethanone, 1-phenyl- Acetophenone 0.29900000

Benzeneacetaldehyde, a-

93-53-8 Hydratropic aldehyde 0.29400000 methyl-

Propanoic acid, 2-methyl-,

80118-06-5 1 ,3 -dimethyl-3 -buten- 1 -yl Iso Pentyrate 0.28500000 ester

557-48-2 2,6-Nonadienal, (2E,6Z)- E Z-2,6-Nonadien-l-al 0.28000000

Pyrazine, 2-methoxy-3-(2- 2-Methoxy-3-Isobutyl

24683-00-9 0.27300000 methylpropyl)- Pyrazine

Formic acid, phenylmethyl

104-57-4 Benzyl Formate 0.27300000 ester

Benzene, l-methoxy-4-

104-45-0 Dihydro anethole 0.26600000 propyl-

Cyclohexanone, 5-methyl-

491-07-6 2-(l-methylethyl)-, (2R, Iso Menthone 0.25600000

5tf)-rel-

Cyclohexanone, 5-methyl-

89-80-5 2-(l-methylethyl)-, (2R, Menthone Racemic 0.25600000

5S)-rel-

2463-53-8 2-Nonenal 2 Nonen-l-al 0.25600000

Cyclohexanone, 2-ethyl-4,

55739-89-4 Thuyacetone 0.25000000

4-dimethyl-

Hydroquinone Dimethyl

150-78-7 Benzene, 1,4-dimethoxy- 0.25000000

Ether Benzene, 1-

64988-06-3 (ethoxymethyl)-2- Rosacene 0.24600000 methoxy-

Bicyclo[2.2. l]heptan-2-

76-22-2 Camphor gum 0.22500000 one, 1,7,7-trimethyl-

2-Hexene, 6,6-dimethoxy-

67674-46-8 Methyl Pamplemousse 0.21400000

2,5,5-trimethyl-

112-31-2 Decanal Decyl Aldehyde 0.20700000

Benzenepropanal, β-

16251-77-7 Trifernal 0.20600000 methyl-

Benzenemethanol, a- Methylphenylc arbinol

93-92-5 0.20300000 methyl-, 1 -acetate Acetate

143-13-5 Acetic acid, nonyl ester Nonyl Acetate 0.19700000

Ethanone, l-(4-

122-00-9 Para Methyl Acetophenone 0.18700000 methyiphenyl)-

2H-Pyran, 6-butyl-3,6-

24237-00-1 Gyrane 0.18600000 dihydro-2,4-dimethyl-

Propanoic acid, 2-methyl-,

41519-23-7 Hexenyl Isobutyrate 0.18200000

(3Z)-3-hexen-l-yl ester

93-89-0 Benzoic acid, ethyl ester Ethyl Benzoate 0.18000000

3-Octanol, 3,7-dimethyl-,

20780-48-7 Tetrahydro Linalyl Acetate 0.18000000

3 -acetate

101-41-7 Methyl 2-phenylacetate Methylphenyl acetate 0.17600000

1-Hexanol, 5-methyl-2-(l- Tetrahydro Lavandulyl

40853-55-2 0.17300000 methylethyl)-, 1 -acetate Acetate

Cyclohexanol, 3,3,5-

933-48-2 Trimethylcyclohexanol 0.17300000 trimethyl-, (lR,5R)-rel-

2-Hexenal, 5-methyl-2-(l-

35158-25-9 Lactone of Cis Jasmone 0.17200000 methylethyl)-

7-Octen-2-ol, 2,6-

18479-58-8 Dihydromyrcenol 0.16600000 dimethyl-

Acetic acid, phenylmethyl

140-11-4 Benzyl acetate 0.16400000 ester

Cyclohexanone, 2-(l- 2-sec-Butyl Cyclo

14765-30-1 0.16300000 methylpropyl)- Hexanone

20125-84-2 3-Octen-l-ol, (3Z)- Octenol 0.16000000

Heptanoic acid, 2-propen-

142-19-8 Allyl Heptoate 0.16000000

1-yl ester

100-51-6 Benzenemethanol Benzyl Alcohol 0.15800000

Butanoic acid, 2-methyl-,

10032-15-2 Hexyl-2-Methyl Butyrate 0.15800000 hexyl ester 14. 2(3H)-Furanone, 5-

695-06-7 Gamma Hexalactone 0.15200000 ethyldihydro-15. Cyclohexaneethanol, 1-

21722-83-8 Cyclohexyl Ethyl Acetate 0.15200000 acetate

16. 2-Nonenoic acid, methyl

111-79-5 Methyl-2-Nonenoate 0.14600000 ester

17. Butanoic acid, (3Z)-3-

16491-36-4 Cis 3 Hexenyl Butyrate 0.13500000 hexen-l-yl ester

18. 2-Octynoic acid, methyl

111-12-6 Methyl Hep tine Carbonate 0.12500000 ester

19. 1,3-Oxathiane, 2-methyl-

59323-76-1 Oxane 0.12300000

4-propyl-, (2R,45)-rel-20. Heptanal, 6-methoxy-2,6-

62439-41-2 Methoxy Melonal 0.11900000 dimethyl-21. Bicyclo[2.2. l]heptan-2-ol,

13851-11-1 Fenchyl Acetate 0.11700000

1,3,3-trimethyl-, 2-acetate

22. l,6-Octadien-3-ol, 3,7-

115-95-7 Linalyl acetate 0.11600000 dimethyl-, 3 -acetate

23. 18479-57-7 2-Octanol, 2,6-dimethyl- Tetra-Hydro Myrcenol 0.1150000024. 78-69-3 3,7-dimcthyIoctan-3-ol Tetra-Hydro Linalool 0.1150000025. 111-87-5 1-Octanol Octyl Alcohol 0.1140000026. 3 -Cyclohexene- 1 -

71159-90-5 methanethiol, α,α,4- Grapefruit mercaptan 0.10500000 trimethyl-27. Cyclohexanemethanol, a,

80-25-1 Menthanyl Acetate 0.10300000 a,4-trimethyl-, 1-acetate

28. Cyclohexanol, 2-(l,l-

88-41-5 Verdox™ 0.10300000 dimethylethyl)-, 1-acetate

29. Cyclohexanol, 4-(l,l-

32210-23-4 Vertenex 0.10300000 dimethylethyl)-, 1-acetate

30. 112-44-7 Undecanal n-Undecanal 0.1020000031. 124-19-6 Nonanal Nonanal Aldehyde C-9 0.5320000032. 929253-05- 6-methoxy-2,6- 6-methoxy-2,6-dimethyl

0.04020000 4 dimethyloctanal octanal

33. 2-propan-2-

68039-47-4 Phenethyl Isopropyl Ether 0.24900000 yloxyethylbenzene

34. ethyl 2-(2-methyl-l,3-

6413-10-1 Apple Ketal 0.21900000 dioxolan-2-yl)acetate

35. 106-23-0 3,7-dimethyloct-6-enal citronellal 0.21500000

Vapor Pressures are acquired as described in the Test Methods Section.

Origin: Same as for Table 1 hereinabove. Exemplary high volatile fragrance materials selected from the group of Table 3 High Volatile Fragrance Materials are preferred. However, it is understood by one skilled in the art that other high volatile fragrance materials, not recited in Table 3, would also fall within the scope of the present invention, so long as they have a vapor pressure of greater than 0.1 Torr (0.0133 kPa) at 25 °C.

Preferably, the compositions of the present invention, wherein: (i)(c) the high volatile fragrance material is selected from the group of Table 3 High Volatile Fragrance Materials 1, 2, 6, 8, 9, 12, 14, 19, 36, 39, 46, 47, 56, 57, 58, 60, 62, 74, 78, 93, 94, 96, 100, 106, 111, 117, 119, 120, 128, 129, 131-135 and mixtures thereof; and (ii) the substantially non-odorous fragrance modulator is selected from the group of Table 4(a) Substantially Non-Odorous Fragrance Modulators 1-5, and mixtures thereof.

Preferably, the compositions of the present invention, wherein: (i)(c) the high volatile fragrance material is selected from the group consisting of Table 3 high Volatile Fragrance Materials 1, 2, 6, 8, 9, 12, 14, 19, 36, 39, 46, 47, 56, 57, 58, 60, 62, 74, 78, 93, 94, 96, 100, 106, 111, 117, 119, 120, 128, 129, 131-135, and mixtures thereof; and (ii) the substantially non- odorous fragrance modulator is selected from the group of Table 4(a) Substantially Non-Odorous Fragrance Modulators 6-8, and mixtures thereof.

Preferably, the compositions of the present invention, the high volatile fragrance material is selected from the group (as described herein above), and wherein this group of high volatile fragrance material has at least about 20 wt%, at least about 30 wt%, at least about 40 wt%, at least about 50 wt%, at least about 60 wt%, or at least about 70 wt%, relative to the total weight of the high volatile fragrance material.

Fragrance Modulators

In one aspect, compositions of the present invention comprise at least one substantially non-odorous modulator selected from the group consisting of:

(a) Methyl Glucoside Polyol; Ethyl Glucoside Polyol; Propyl Glucoside Polyol; and their mixtures;

(b) Isocetyl Alcohol;

(c) PPG-3 Myristyl Ether; Neopentyl Glycol Diethylhexanoate; and their mixtures;

(d) Sucrose Laurate, Sucrose Dilaurate, Sucrose Myristate, Sucrose Palmitate, Sucrose

Stearate, Sucrose Distearate, Sucrose Tristearate, and mixtures thereof; (e) Trimethylcyclohexane derivatives having the formula (I):

wherein:

n is 0, 1 or 2;

A is C=0 or CH-OH;

R ^la is hydrogen or methyl;

R ^a is a C ₂ -C ₁ 0 hydrocarbon group; and

is a saturated or unsaturated carbon-carbon bond;

(f) L-menthoxy ether derivatives having the formula (II):

wherein:

m is 0, 1 or 2;

B is hydrogen or OH; and

C is hydrogen or methyl;

(g) Tetra-hydronaphthalene derivatives having the formula (III):

wherein: R is hydrogen or methyl; and

R ^2b is alkyl;

(h) Hyaluronic acid disaccharide sodium salt, sodium hyaluronate and their mixtures;

(i) Ether derivatives having the formula (IV) or formula (V):

C ₅ H _/ O _m -(OR ^lc ) _n (IV) wherein:

C ₅ H _/ C is a pentose residue, wherein / is an integer from 6 to 9, and m is an integer from 1 to 4;

n is an integer from 1 to 4; and

R ^lc is C ₄ -C ₂₀ hydrocarbon group; and

C ₆ H _x O _y -(OR ^ld ) _z

(V) wherein:

C ₆ H _x O _y is a hexose residue, wherein x is an integer from 7 to 11, and y is an integer from 1 to 5;

z is an integer from 1 to 5; and

R ^ld is C ₄ -C ₂₀ hydrocarbon group; and

(]) Diethylene Glycol Ether derivatives having the formula (VI) or formula (VII):

C ₅ H _c O _d -(OCH ₂ CH ₂ -0-CH ₂ CH ₂ -0-R ^le ) _e

(VI) wherein:

CsH _c O _d is a pentose residue, wherein c is an integer from 6 to 8, and d is an integer from 1 to 3;

e is an integer from 2 to 4; and

R ^le is Ci-C ₆ alkyl group; and C ₆ H _f O _g -(OCH2CH ₂ -0-CH ₂ CH ₂ -0-R ^li ) _h

(VII) wherein:

C ₆ H _f O _g is a hexose residue, wherein f is an integer from 7 to 10, and g is an integer from 1 to 4;

h is an integer from 2 to 5; and

If

R is Ci-C ₆ alkyl group;

(k) Hydroquinone Glycoside derivatives having the formula (VIII):

(VIII) wherein:

R ^g is selected from the group consisting of: (i) pentose residue, hexose residue, aminosaccharide residue, uronic acid residue and their mixtures; (ii) methylated versions of group (i); and (iii) mixtures of groups (i) and (ii); and

(1) Propylene Glycol Propyl Ether; Dicetyl Ether; Polyglycerin-4 Ethers; Isoceteth-5;

Isoceteth-7, Isoceteth-10; Isoceteth-12; Isoceteth-15; Isoceteth-20; Isoceteth-25;

Isoceteth-30; Disodium Lauroamphodipropionate; Hexaethylene glycol monododecyl ether; and their mixtures;

(m)Neopentyl Glycol Diisononanoate; Cetearyl Ethylhexanoate; and their mixtures;

(n) Glyceryl Ether derivatives having the formula (IX):

wherein:

R is C4-C12 aliphatic hydrocarbon group;

(o) Panthenol Ethyl Ether, DL-Panthenol and their mixtures; (p) Aliphatic Dibasic Acid Diester derivatives having the formula (X):

_R i i _0C0 R2i _C00R : 3i

(X)

wherein:

R ⁿ is C ₄ -C5 alkyl;

R ²¹ is C ₄ alkylene; and

FT is C ₄ -C5 alkyl; and (q) Aliphatic Ether derivatives having the formula (XI):

R ⁴ⁱ -0-(CH(CH ₃ )-CH ₂ 0) _a -(CH ₂ -CH ₂ 0) _b

wherein:

a and b are integers such that the sum of a and b is from 1 to 4; and R ⁴¹ is an aliphatic chain comprising from 8 to 18 carbons;

(r) N-hexadecyl n-nonanoate, Noctadecyl n-nonanoate and their mixtures;

(s)Tricyclodecane Amide derivatives selected from the group consisting of:

(i) the compounds of formula (XII):

(ΧΠ)

wherein:

X is selected from:

Y is hydrogen, or a halogen; and

each R ¹ ^ is independently selected from a hydrogen, or C ₁ -C4 alkyl;

(ii) the compounds of formula (XIII):

wherein:

each R ² ^ is independently selected from a hydrogen, methyl, ethyl or C ₃

2e Ci8 alkyl, cycloalkyl or cycloheteroalkyl, with the proviso that both R groups are not hydrogen; and

(iii) mixtures of the compounds of formulae (XII) and (XIII); and

(t) mixtures thereof. Preferably, the substantially non-odorous fragrance modulator is selected from the group of materials disclosed in Table 4(a).

Table 4(a): Substantially Non-Odorous Fragrance Modulators

CAS

No. Group Chemical Name Supplier

Number

1. 61849-72-

PPG- 10 Methyl Glucose Ether

7

2. 61849-72-

PPG-20 Methyl Glucose Ether ^; Lubrizol

7

3. 68239-42-

(a) Ethoxylated Methyl Glucose Ether

9

4. 68515-73-

Caprylyl/Capryl Glucoside ³ BASF

1

5. SEPPIC

Undecyl Glucoside ^3a —

(France)

Ashland

6. 36653-82-

(b) Isocetyl Alcohol ⁴ Speciality

4

Ingredients

7. PPG-3 Myristyl Ether ⁵ — Evonik

(c)

8. 28510-23-

Neopentyl Glycol Diethylhexanoate ⁶ Lubrizol

8

9. 25339-99- Alfa Chemicals

Sucrose Laurate

5 Ltd. (UK)

10. 25915-57- Alfa Chemicals

Sucrose dilaurate

5 Ltd. (UK)

11. 27216-47- Mitsubishi

(d) Sucrose Myristate

3 Chemicals

12. 26446-38-

Sucrose Palmitate

8 Alfa Chemicals

13. 25168-73- Ltd. (UK)

Sucrose Stearate

4

14. 27195-16- Mitsubishi

Sucrose Distearate

0 Chemicals (JP)

15. 27923063- Mitsubishi

Sucrose Tristearate

3 Chemicals (JP)

16. (E)-l-(2,2,6-trimethylcyclohexyl)oct-l-en-3- Takasago

(e) - one ^s (Japan)

17. 2-(l-menthoxy)ethane-l-ol ⁹ -

18. l-(l-menthoxy)propane-2-ol ⁹ -

Takasago

19. (f) (Japan)

3-(l-menthoxy)propane-l-ol ⁹ —

20. 3-(l-menthoxy)propane-l,2-diol ⁹ —

TetraMs-0-(3,6-dioxaheptanyl)-xylopyranose ¹³ —

Bis-0-(3,6-dioxadodecanyl)-glucopyranose ¹³ —

Tris-0-(3,6-dioxadodecanyl)-glucopyranose ¹³ —

Tetrakis-0-(3,6-dioxadodecanyl)-glucopyranose

13 —

Pentakis-0-(3,6-dioxadodecanyl)-

—

glucopyranose ⁷³

(k) Hydroquinone beta-D-glycoside ¹⁴ 497-76-7 Shiseido

Propylene Glycol Propyl Ether 1569-01-3 Sigma Aldrich

Dicetyl Ether 4113-12-6 (UK)

25618-55- Solvay

Polyglycerin-4 Ethers

7 Chemicals

69364-63-

Isoceteth-5

2

69364-63-

Isoceteth-7

2

69364-63-

Isoceteth-10

2

69364-63-

Isoceteth-12 Nihon

(1) 2

Emulsion

69364-63-

Isoceteth-15 Company Ltd.

2

69364-63-

Isoceteth-20

2

69364-63-

Isoceteth-25

2

69364-63-

Isoceteth-30

2

68929-04-

Disodium Lauroamphodipropionate Rhodia

4

Sigma Aldrich

Hexaethylene glycol monododecyl ether ^14b 3055-96-7

(UK)

27841-07-

Neopentyl Glycol Diisononanoate ¹⁵

2 Symrise

(m)

90411-68- (Germany)

Cetearyl Ethylhexnoate ¹⁶

0

(n) 2-ethylhexyloxypr 17 70455-33- opanediol Takasago (JP)

9

DSM

(o) Panthenol Ethyl Ether ¹⁸ 667-83-4 Nutritional

Products, Inc.

² available as Glucam™ E-20.

³ available as Plantacare ^® 810 UP.

3 ^a available as Simulsol ^® SL 11W.

4 available as CERAPHYL ^® ICA.

⁵ available as Tegosoft ^® APM.

⁶ available as Schercemol™ NGDO.

⁷ disclosed in U.S. Patent No. 6,737,396B2 (Firmenich), column 1, lines 43-47.

diclosed as compound l'i in U.S. Patent No. 6,440,400B1 (Takasago Int. Corp.), col. 5.

8 ^a diclosed in U.S. Patent No. 4,313,855 (Dragoco Gerberding & Co. GmbH), col. 1, lines 12-13. ⁹ disclosed in U.S. Patent No. 7,538,081B2 (Takasago Int. Corp.), column 7, lines 50-53. disclosed in U.S. Patent No. 6,147,049 (Givaudan Roure), col. 5, line 24, to col. 6, line 17. " disclosed in PCT Publication No. WO85/04803 (Diagnostic), pg. 2, line 1 to pg. 4, line 2. ¹² disclosed in JP Patent No. 61-083114 (Kanebo).

"disclosed in JP Patent No. 61-063612 (Kanebo).

1 ⁴ disclosed in JP Patent No. 62-084010 (Shiseido).

1 ^4b available as: Laureth-6.

"disclosed in U.S. Patent Publication No. 2011/0104089A1 (Symrise), para. [0001].

1 ⁶ available as PCL-Liquid ^® 100.

"disclosed in U.S. Patent No. 7,196,052 (Takasago Int. Corp.), col. 4, lines 34-35.

"disclosed in EP Patent Publication No. 616800A2 (Givaudan), pg. 2, lines 12-25.

"disclosed in U.S. Patent No. 4,110,626 (Shiseido), column 3, lines 54-56.

^19a disclosed in PCT Publication No. WO2014/155019 (LVMH).

^19b disclosed in U.S. Patent No. 9,050,261 (Symrise).

²⁰ disclosed as compounds C1-C22 in WO2014/139952 (Unilever).

2 ¹ available as Expert Gel ^® EG56.

²² available as Kolliphor ^® EL.

²³ disclosed in U.S. Patent No. 9,050,261 (Symrise).

Preferably, the substantially non-odorous fragrance modulator is selected from the group of materials disclosed in Table 4(b).

Table 4(b): Substantially Non-Odorous Fragrance Modulators

CAS

No. Chemical or INCI Name Trade Name Supplier

Number

68131- Sigma Aldrich

1. C12-14 Sec-Pareth-3 Tergitol ^® 15-S-7

40-8 (UK)

Poly(ethylene glycol-ran-

9038- Sigma Aldrich

2. propylene glycol) monobutyl PPG-7-Buteth-10

95-3 (UK) ether

37311- Chemical

3. PPG-4-Ceteth-10 Nikkol PBC-33

01-6 Navi

Ethox

5703-

4. Deceth-4 Ethal DA-4 Chemicals,

94-6

Inc.

A & E

9087- Connock

5. PPG-5-Ceteth-20 AEC PPG-5-Ceteth-20

53-0 (Perfumery &

Cosmetics) Ltd.

Shell

Neodol 45-7 alcohol 68951-

C14-15 Pareth-7 Chemical ethoxylate 67-7

Company

Linear alcohol (C12-15) Pareth- 68131-

Bio-soft N25-7 Stephan 3ethoxylate, POE-7 39-5

Company

Linear alcohol (C12-13) Pareth- 66455-

Bio-soft N23-6.5 (USA) 3ethoxylated, POE-6.5) 14-9

Polyethylene glycol 1100

68439- Sigma Aldrich mono(hexadecyl/octadecyl) Cremophor ^® A 25

49-6 (UK) ether

Stephan

Linear alcohol (C9-11) 68439-

Bio- soft N91-8 Company ethoxylated POE -8 Pareth-3 46-3

(USA)

Coceth-lO or

61791- Sigma Aldrich Polyoxyethylene (10) dodecyl Genapol ^® C-100

13-7 (UK) ether

Solvay

68439-

Alcohols, C12-14, ethoxylated Rhodasurf ^® LA 30 Solutions

50-9

Italia S.p.A.

Poly(ethylene glycol) methyl Poly(ethylene glycol) 9004- Sigma Aldrich ether methyl ether 74-4 (UK)

Shell

68002-

C 10- 16 Pareth- 1 Neodol ^® PC 110 Chemical

97-1

Company

25231-

PPG- 11 Stearyl Ether Arlamol™ PS HE Croda (UK)

21-4

9005- Sigma Aldrich

Steareth-100 Brij ^® S100

00-9 (UK)

Polyethylene glycol hexadecyl 9004- Sigma Aldrich

Brij ^® C-58

ether 95-9 (UK)

9003- Sigma Aldrich

Pluronic ^® F-127 Pluronic ^® F-127

11-6 (UK)

Linear Alcohol (CI 1) 34398- Stepan

Bio-soft Nl-5

Ethoxylate, POE-5 01-1 Canada Inc.

6540- Evonik

Laureth-10 Intrasol FA 12/18/10

99-4 Industries AG

Decaethylene glycol Polyoxyethylene (10) 9002- Sigma Aldrich mono-dodecyl ether lauryl ether 92-0 (UK)

Ethylene glycol monomethyl 109-86- Sigma Aldrich

2-Methoxyethanol

ether 4 (UK)

Grau

27306- Aromatic s

Myreth-4 Homulgator 920 G

79-2 GmbH &

Company KG

Oleth-16 Pegnol 0-16A 25190- Toho Alkoxylated Alcohols 05-0 Chemical

Industry Co., Ltd.

Nihon

52292- Emulsion

Isosteareth-5 Emalex 1805

17-8 Company,

Ltd.

9035-

PPG-lO Cetyl Ether Arlamol™ PC 10 Croda (UK)

85-2

Polyoxy (ethylene glycol) (18) Poly(ethylene glycol) 24938- Sigma- tridecyl ether (18) tridecyl ether 91-8 Aldrich (UK)

Sasol

Poly(oxy- 1 ,2-ethanediyl) , a- ALFONIC ^® 10-8 26183- Chemicals decyl-w-hydroxy- Ethoxylate 52-8

(USA) LLC

4536-

Laureth- 1 Mackam™ 2LSF Rhodia (DE)

30-5

Ethox

PEG- 5 Hydrogenated Tallow 61791-

Ethox HTAM-5 Chemicals, Amine 26-2

Inc.

Nikko

26635-

PEG- 15 Oleamine Nikkol TAMNO-15 Chemicals

93-8

Co., Ltd.

9004- Sigma Aldricholyoxyethylene (20) oleyl ether Brij ^® O20-SS

98-2 (UK)

8065-

Cetoleth-10 Brij ^® CO10 Croda, Inc.

81-4

Sanyo

61791-

Talloweth-7 Emulmin 70 Chemical

28-4

Industries Ltd.

Isobutoxypropanol 34150-

Isobutoxyprop anol MolPort Alcohols 35-1

AKos

Isobutoxypropanol 23436-

Isobutoxyprop anol Consulting & Alcohols 19-3

Solutions

111-46-

Diethylene Glycol Twincide EDG Roda

6

Toho

109-86- Chemical

Methoxyethanol Hisolve MC

4 Industry Co.,

Ltd.

Ethoxyethanol 110-80- Sigma-

2- Ethoxyethanol

Alcohols 5 Aldrich (UK)

The Dow

Methoxyisopropanol 107-98-

Dowanol™ PM Chemical Alcohols 2

Company

Methoxyethanol Hisolve MC 32718- Toho 54-0 Chemical

Industry Co., Ltd.

Methylal 109-87- Sigma-

Dimethoxymethane

Ethers 5 Aldrich (UK)

Hans

2517- Schwarzkopf

3 -Methoxybutanol Methoxybutanol

43-3 GmbH / Co.

KG

Shell

111-76-

Butoxyethanol Butyl OXITOL Chemical

2

Company

5131-

The Dow

66-

Propylene Glycol n-Butyl Ether Dowanol™ PnB Chemical

8/29387

Company -86-8

Propylene Glycol Butyl 15821- Sigma Aldrich

Propylene Glycol Butyl Ether

Ether 83-7 (UK)

Diethylene glycol butyl 112-34- Sigma Aldrich

2-(2-butoxyethoxy)ethanol

ether 5 (UK)

52019-

Deceth-4 Phosphate Crodafos™ D4A Croda, Inc.

36-0

Ethylene glycol 2136- Sigma-

2-(Hexadecyloxy)ethanol

monohexadecyl ether 71-2 Aldrich (UK)

Poly(propylene glycol) Poly(propylene glycol) 9003- Sigma- monobutyl ether monobutyl ether 13-8 Aldrich (UK)

The Dow

30136-

Propylene Glycol Propyl Ether Dowanol™ PnP Chemical

13-1

Company

29387-

The Dow

86-

Propylene Glycol n-Butyl Ether Dowanol™ PnB Chemical

8/5131- Company 66-8

Di(propylene glycol)

Dipropylene glycol monomethyl 34590- Sigma Aldrich methyl ether, mixture of

ether 94-8 (UK) isomers

The Dow

Dipropylene Glycol Dimethyl 111109-

Proglyde™ DMM Chemical Ether 77-4

Company

The Dow

13429-

PPG-2 Methyl Ether Dowanol™ DPM Chemical

07-7

Company

Methoxydiglycol 111-77- Orient Stars

OriStar DEGME

Ethers 3 LLC

Di(ethylene glycol) ethyl 111-90- Sigma Aldrich

Diethylene glycol ethyl ether

ether 0 (UK) 16057-

76. Steareth-2 Brij ^® S2 Croda, Inc.

43-5

8065-

77. Cetoleth-10 Brij ^® CO10 Croda, Inc.

81-4

Trimethyl Pentanol

Trimethyl Pentanol 68959- Angene

78. Hydroxyethyl Ether

Hydroxyethyl Ether 25-1 Chemical Alcohols

109292-

79. Steareth-10 Allyl Ether Salcare ^® SC80 BASF

17-3

1733- Angene

80. TEA-Lauryl Ether material ID- AG-J-99109

93-3 Chemical

71032-

81. Polyglyceryl-2 Oleyl Ether Chimexane NB Chimex

90-1

544-62- Sigma-

82. Batyl Alcohol B402 ALDRICH

7 Aldrich (UK)

5117- Sigma-

83. Octaethylene Glycol 15879 ALDRICH

19-1 Aldrich (UK)

66082-

84. Triglycerol diisostearate Cithrol™ Croda (UK)

42-6

Sakamoto

59113- Yakuhin

85. Diglycerin Diglycerin 801

36-9 Kogyo Co.,

Ltd.

Sakamoto

25618- Yakuhin

86. Polyglycerin #310 Polyglycerin #310

55-7 Kogyo Co.,

Ltd.

Sasol

6297-

87. Distearyl Ether Cosmacol® SE Germany

03-6

GmbH

AKos

10438-

88. Caprylyl Glyceryl Ether Caprylyl Glyceryl Ether Consulting &

94-5

Solutions

Nikko

506-03-

89. Chimyl Alcohol Chimyl Alcohol Chemicals

6

Co., Ltd.

Lipo

Dipentaerythrityl 68130-

90. Liponate ^® DPC-6 Chemicals, Hexacaprylate/Hexacaprate 24-5

Inc.

110-91- Sigma-

91. Morpholine 394467 ALDRICH

8 Aldrich (UK)

The Dow

51200-

92. Dimethyl Oxazolidine OXABAN™ -A Chemical

87-4

Company

Ethyl Hydroxymethyl Oleyl 68140- Angene

93. 4-Oxazolemethanol

Oxazoline 98-7 Chemical Methyl Hydroxymethyl Oleyl 14408- Adeka

94. Adeka Nol GE-RF

Oxazoline 42-5 Corporation

637-58- Orient Stars

95. Pramoxine HC1 OriStar PMHCL

1 LLC

57448-

96. Allantoin Ascorbate Allantoin Ascorbate ABI Chem

83-6

Stearamidopropyl Morpholine 55852-

97. Mackalene™ 326 Rhodia Inc.

Lactate 14-7

646-06- Lambiotte &

98. Dioxolane Elcotal DX

0 CIE S.A.

5464- Sigma Aldrich

99. Glycerol Formal Glycerol Formal

28-8 (UK)

55852-

100. Stearamidopropyl Morpholine Mackine 321 Rhodia Inc.

13-6

2,4,6- Poly(melamine-co-

68002- Sigma-

101. Tris[bis(methoxymethyl)amino] formaldehyde)

20-0 Aldrich (UK) -1,3,5-triazine methylated

11111-

102. Poloxamine 1307 Pluracare ^® 1307 BASF

34-5

27177-

103. Nonoxynol-8 Igepal ^® CO-610 Rhodia Inc.

05-5

27177-

104. Nonoxynol-10 Igepal ^® CO-710 Rhodia Inc.

08-8

Nikko

2315-

105. Octoxynol-10 Nikkol OP- 10 Chemicals

66-4

Co., Ltd.

68987-

106. Nonoxynol-9 Igepal ^® CO-630 Rhodia Inc.

90-6

94349- Angene

107. Nonoxynol-9 Iodine Nonoxynol-9 iodine

40-3 Chemical

Octylphenoxy

68987-

108. poly(ethyleneoxy)ethanol, Igepal ^® CA-630 Rhodia Inc.

90-6

branched

The Dow

Sodium Octoxynol-2 Ethane 55837-

109. Triton™ X-200 Chemical

Sulfonate 16-6

Company

14548- Lanxess

110. B enzylhemiformal Preventol D2

60-8 Corporation

27176-

111. Nonoxynol-2 Igepal ^® CO-210 Rhodia Inc.

93-8

The Dow

2315-

112. Octoxynol-3 Igepal® CA-420 Chemical

62-0

Company

Sasol

27176-

113. Nonoxynol-3 Marlophen NP 3 Germany

95-0

GmbH 7311-

114. Alkoxylated Alcohols Alkasurf NP-4 Rhodia Inc.

27-5

Triethylene Glycol Santa Cruz

51437-

115. Nonoxynol-3 Mono(p-nonylphenyl) Biotechnolog

95-7

Ether y

Jos. H.

27177-

116. Nonoxynol-7 Lowenol 2689 Lowenstein &

03-3

Sons, Inc.

27177-

117. Nonoxynol-6 Igepal ^® CO-530 Rhodia Inc.

01-1

20636-

118. Nonoxynol-5 Igepal ^® CO-520 Rhodia Inc.

48-0

26264-

119. Nonoxynol-5 Igepal ^® CO-520 Rhodia Inc.

02-8

27176-

120. Nonoxynol-4 Alkasurf NP-4 Rhodia Inc.

97-2

Nikko

102051-

121. Polyglyceryl-10 Trioleate Nikkol Decaglyn 3-OV Chemicals

00-3

Co., Ltd.

Nikko

33940-

122. Polyglyceryl-10 Dioleate Nikkol Decaglyn 2-0 Chemicals

99-7

Co., Ltd.

34424- Abitec

123. Polyglyceryl-10 Tetraoleate Caprol 10G40

98-1 Corporation

Nikko

Nikkol Decaglyn 1-SV 79777-

124. Polyglyceryl-10 Stearate Chemicals

EX 30-3

Co., Ltd.

Sakamoto

79665- Yakuhin

125. Polyglyceryl-10 Oleate S-Face O-1001 P

93-3 Kogyo Co.,

Ltd.

Nikko

Nikkol Decaglyn 1-MV 87390-

126. Polyglyceryl-10 Myristate Chemicals

EX 32-7

Co., Ltd.

34406- Dr.

127. Dermofeel ^® G 10 L Dermofeel ^® G 10 L

66-1 Straetmans

51033- Chemical

128. Polyglyceryl-6 Laurate NIKKOL Hexaglyn 1-L

38-6 Navi

Sakamoto

126928- Yakuhin

129. Polyglyceryl-6 Isostearate S-Face IS-601 P

07-2 Kogyo Co.,

Ltd.

Nihon

27321- Emulsion

130. Choleth-10 Emalex CS-10

96-6 Company,

Ltd. Steareth-10 Allyl 109292-

131. Salcare ^® SC80 BASF Ether/ Acrylates Copolymer 17-3

9003- Phoenix

132. Polyvinyl Stearyl Ether Giovarez ^® 1800

96-7 Chemical, Inc.

Sasol

133. Dicetyl Ether Cosmacol Ether 16 - Germany

GmbH

Pola Chemical

9038-

134. PPG-23-Steareth-34 Unisafe 34S-23 Industries,

43-1

Inc.

17517-

135. Stearoxypropyl Dimethylamine Farmin DM E-80 Kao Corp.

01-0

Sasol

6297-

136. Distearyl Ether Cosmacol SE Germany

03-6

GmbH

A & E Connock

55353-

137. Polyquaternium- 10 AEC Polyquaternium- 10 (Perfumery &

19-0

Cosmetics) Ltd.

629-82- Sigma Adlrich

138. Octyl ether Dioctyl ether

3 (UK)

EMD

139. Ethyl Ether Diethyl Ether 60-29-7

Chemicals

Methyl Hexyl Ether 4747- TCI

140. methyl hexyl ether

Ethers 07-3 AMERICA

Nihon

94159- Emulsion

141. Ceteth-12 Emalex 112

75-8 Company,

Ltd.

Ceteth-10 or cetyl alcohol POE- 14529- Jeen

142. Jeecol CA-10

10 40-9 International

13149- Jeen

143. Steareth-10 Jeecol SA-10

86-5 International

Nonaethylene glycol Nonaethylene glycol 3055- Sigma Aldrich

144.

monododecyl ether monododecyl ether 99-0 (UK)

71976-

145. Oleth-10 Brij ^® O10 Croda, Inc.

00-6

24871-

146. Oleth-10 Brij ^® O10 Croda, Inc.

34-9

The Dow

6790-

147. PEG- 12 Carbowax™ PEG 600 Chemical

09-6

Company

3386-

148. PEG-9 Sabopeg 400 Sabo s.p.a.

18-3

149. PEG- 10 DECAETHYLENE 5579- MolPort 95-6 America, Inc.

Jeen

59970-

167. Steareth-4 Jeecol SA-4 International

10-4

Corporation

5274-

168. Laureth-4 Brij ^® L4 Croda, Inc.

68-0

Grau

39034- Aromatic s

169. Myreth-4 Homulgator 920 G

24-7 GmbH &

Company KG

5274- Protameen

170. Ceteth-4 Procol CA-4

63-5 Chemicals

5353-

171. Oleth-4 Chemal OA-4 Chemax, Inc.

26-4

103622-

172. Oleth-4 Chemal OA-4 Chemax, Inc.

85-1

497926-

173. Polyimide- 1 Aquaflex™ XL-30 Chemwill

97-3

Polymethoxy Bicyclic 56709- Angene

174. Caswell No. 494CA

Oxazolidine 13-8 Chemical

Angus

Hydroxymethyl 6542-

175. Zoldine™ ZT Chemical

Dioxoazabicyclooctane 37-6

Company

5 -Ethyl- 1 - aza- 3 ,7 -

Dihydro-7a-ethyloxazolo[3,4- 7747- Sigma Aldrich

176. dioxabicyclo [3.3.0] octan

c]oxazole 35-5 (UK) e

32647- Roquette

177. Dibenzylidene Sorbitol Disorbene ^®

67-9 America, Inc.

135861- Milliken

178. Dimethyldibenzylidene Sorbitol Millad ^® 3988

56-2 Chemicals

Alfonic 1216CO-2 3055- Sasol North

179. Laureth-2

Ethoxylate 93-4 America, Inc.

2-(2-Butoxyethoxy)ethyl (6- Sigma-

180. Piperonyl Butoxide 51-03-6

propylpiperonyl) ether Aldrich (UK)

63187-

181. Menthone Glycerin Acetal Frescolat ^® MGA Symrise

91-7

68332-

182. Propylene Glycol Caprylate Mackaderm PGC Rhodia Inc.

79-6

67674-

183. Diethoxynonadiene SBB016951 Ambinter

36-6

Takasago

Menthoxypropanediol 87061-

184. Coolact ^® 10 International

Alcohols 04-9

Corporation

2-Diphenylmethoxy-N,N-

147-24- Sigma-

185. dimethylethylamine Diphenhydramine HC1

0 Aldrich (UK) hydrochloride 186. 3-((2-ethylhexyl)oxy)propane- 70445-

- - 1,2-diol 33-9

3-((2-propylheptyl)oxy)propane-

187. - - - 1,2-diol

l-amino-3-((2- 99509-

188. - —

ethylhexyl)oxy)propan-2-ol 00-9

l-( 1 -Methyl-2-propoxyethoxy)- Di(propylene glycol) 29911- Sigma Aldrich

189.

2-propanol propyl ether 27-1 (UK)

The compounds, as described above in Tables 4(a) and 4(b), act as a substantially non- odorous fragrance modulator of the perceived fidelity and/or longevity of the fragrance profile of the composition of the present invention. For example, the substantially non-odorous fragrance modulators, with a fragrance component having a diamond construction, act to prolong the duration during which the fragrance profile, preferably the characters attributable from the moderate and high volatile fragrance materials, can be perceived as compared to a control composition in the absence of the modulators or having the classical fragrance pyramid three- tiered structure. As another example, the substantially non-odorous fragrance modulators, with a fragrance component having a diamond construction, can improve the fidelity of the fragrance profile, preferably the characters attributable from the moderate and high volatile fragrance materials, such that it remains significantly the same from initial impression to the end as compared to a control composition in the absence of the modulators or having the classical fragrance pyramid three-tiered structure. While not wishing to be bound by theory, it is believed that the substantially non-odorous fragrance modulators associate to the fragrance materials and retard evaporation.

TEST METHODS

The following assays set forth must be used in order that the invention described and claimed herein may be more fully understood.

Test Method 1: Determining Vapor Pressure

In order to determine the vapor pressure for the fragrance materials, go to the website https://scifinder.cas.org/scifinder/view/scifinder/scifinder Explore.isf and follow these steps to acquire the vapor pressure.

1. Input the CAS registry number for the particular fragrance material.

2. Select the vapor pressure from the search results. 3. Record the vapor pressure (given in Torr at 25 °C).

SciFinder uses Advanced Chemistry Development (ACD/Labs) Software Version 11.02. (© 1994-2013). If the CAS number for the particular fragrance material is unknown or does not exist, you can utilize the ACD/Labs reference program to directly determine the vapor pressure. Vapor Pressure is expressed in 1 Torr, which is equal to 0.133 kilopascal (kPa).

Test Method 2: Olfactory Tests

In order to show the effect of the substantially non-odorous fragrance modulators and fragrance component having a diamond construction on the perception of fragrance profile in a composition of the present invention, test compositions are made, as described in the Example section, and given to panelists to evaluate.

At the testing facility, 50 μΐ _^ samples of the compositions and the controls are applied to glass slides and placed on a hot plate at 32 °C to represent skin temperature for varying durations. It is important that glass slides of samples that are to be later compared are prepared at the same time. The panelists are asked to evaluate the perceived fragrance profile (intensity and/or character) of each glass slide sample at a given time point. Slides are presented coded so that their identity is not known by the panelists. Within a given time point panelists evaluate the slides in a random order and are able to revisit their assessment as they work through the slides at that time point. Their assessments are recorded. In the subsequent analysis, the data for strength and character comparisons are drawn from the independent assessments carried out at a given time point. Only when using the character difference scale below are any 2 products physically directly compared to each other. Panelists are selected from individuals who are either trained to evaluate fragrances according to the scales below or who have experience of fragrance evaluation in the industry. Typically, around 6-10 panellists are used to evaluate a given product and its control.

(a) Fragrance Intensity:

The panelists are asked to give a score on a scale of 0 to 5 for perceived fragrance intensity according to the odour intensity scale set out in Table 4 herein below.

Table 4 - Odour Intensity Scale

Score Fragrance Intensity

0 None

1 Very Weak 2 Weak

3 Moderate

4 Strong

5 Very Strong

(b) Fragrance Character:

The panelists are asked to assess the fragrance character in one of 2 ways:

i) a score on a scale of 0 to 3 for the dominance of particular characters that are relevant to that particular fragrance, e.g.: fresh, green, watery, floral, rose, muguet, fruity, apple, berry, citrus, creamy, woody, balsamic, amber, musk just to name a few, according to the odour grading scale set out in Table 5(i) herein below;

ii) a score on a scale of 1 to 5 for changes in the perceived fragrance profile change for the test compositions versus the controls according to the odour grading scale set out in Table 5(H) herein below.

Table 5(i) - Character Dominance Odour Grading Scale

Table 5(ii) - Character Difference Odour Grading Scale

Score Fragrance Profile Change

Frargrance profile is unchanged, i.e., no difference between the sample vs.

1 the control.

2 Slight fragrance profile change when compared directly with the control.

3 Moderate fragrance profile but similar character to the control,

4 Large difference in fragrance profile from the control.

5 Total difference in the fragrance profile from the control. The results of the panelists are averaged and then analysed using Analysis of Variance methods. The model treats the subject as a random effect and looks at the impact of product, time and the interaction between product and time. From the analysis the least square means for the product and time interaction are obtained. These means (as well as their confidence intervals) are then plotted to enable comparisons between products at each time point. It should be noted that the confidence levels plotted are intended as a guide, and not as a statistical comparison, as they do not take into account that multiple testing has been performed. As well as a graphical assessment, statistical comparisons between the two products at each of the time points are performed with a Sidak correction for multiple comparisons. The p-values for the product differences are obtained, with p-values < 0.05 indicating a statistical difference between the two products at 5% significance (or 95% confidence).

Test Method 3: Analytical Evaporation Tests

The following test is carried out to demonstrate the improved or enhanced longevity of a fragrance profile of a composition of the present invention vs. a control. In particular, the test measures the effect of a substantially non-odorous fragrance modulator on the evaporation rate of one or more fragrance materials (e.g., 10 PRMs) formulated in a composition. The evaporation response of the fragrance materials to the modulator, as a function of time, is measured through the use of gas chromatography ("GC").

1. A test composition may comprise a substantially non-odorous fragrance modulator (any one of the modulators as disclosed in Tables 4(a) and 4(b)) with either: (i) a fragrance material (any one of the moderate volatile fragrance materials as disclosed in Table 2 and high volatile fragrance materials as disclosed in Table 3), or (ii) a blend of fragrance materials from Tables 2 and 3 (as disclosed as Fragrance Example 6 in Table 11). The test compositions also contain high purity ethanol, such as Hayman 100%EP/BP grade, and deionized water. Samples test compositions are provided in Tables 19(a)- 19(b). All of the ingredients are admixed until evenly distributed in the test compositions.

2. A control composition to the test composition described in 1 above, without the substantially non-odorous fragrance modulator is made in a similar manner to Step 1, except that the missing substantially non-odorous modulator is replaced by deionized water. Sample control compositions are provided in Tables 19(a)-19(b).

An internal standard is needed to correct for variations of the amount of composition dispensed in the evaporation test as well as loss during the GC analysis. The internal standard has a vapor pressure of less than 0.001 Torr (0.000133 kPa) at 25 °C and is soluble in the composition and fragrance material. A suitable non-limiting example of an internal standard is triethyl citrate. The internal standard and fragrance material are admixed until evenly distributed at a level of 90 to 95 parts by weight of fragrance material and the required amount of internal standard to reach 100 parts. This mixture is then use to prepare the sample compositions in Step 1 and 2. Alternatively, the internal standard and test or control composition are admixed until evenly distributed at a level of 99 to 99.75 parts by weight of composition and the required amount of internal standard to reach 100 parts. This resultant solution is used in subsequent steps.

A hotplate is set to a temperature of 32 °C. An aluminum container, such as TA

Instruments T-Zero pan, is placed on the hotplate. 20 μΐ _^ of the test or control composition is introduced in the aluminum container using a micropipette. Alternatively, the aluminum container may be filled with the test or control composition to its full capacity. The time at which this takes place is determined to be time zero (i.e., T = 0). Multiple aluminum containers are prepared and left at the set temperature for pre-determined periods of time, such as for example 30 mins, 1 hr, 2 hrs, 3 hrs, 4 hrs, 5 hrs, 6 hrs, 8 hrs and up to 12 hrs.

The aluminum container is removed from the hotplate at the end of the predetermined time period and transferred by being inserted into a 4 mL glass vial already containing at least 2 mL of highly volatile solvent, such as high purity ethanol or hexane.

The glass vial is mixed using a Heidolph multi REAX shaker, or equivalent, for 5 to 10 mins to extract the fragrance materials into the solvent phase. 1.5 mL of the resultant solution is transferred to a 2 mL GC vial.

The GC vial is analysed on an Agilent GC system 6890 equipped with an autosampler, or equivalent. A GC column such as a DB-5MS, Rxi-5 SilMS model or equivalent phase, with a length of 30 m, an inner diameter of 0.25 mm and a film thickness of 1 μιη is used. The GC parameters are set to the values indicated as follows:

Table 5(iii) - GC Parameters

Gas chromatography with flame ionization detection ("FID") or with mass spectrometry ("MS") can be used for the identification and quantification of fragrance material in the compositions. Either detection system can be used in conjunction with GC. The column dimensions as well as GC settings described in this method, such as injector temperature, carrier gas velocity, temperature ramp and final oven temperature can be adjusted to optimize the response of the fragrance material and internal standard being monitored. The detection system settings, such as FID gas flows and temperature or MS parameters, should be optimized by a trained analyst to enable the precise detection and quantification of the analytes of interest. 8. The peak area of the fragrance material and internal standard are recorded. The peak area ratio of the fragrance material and the internal standard is calculated at each time point for each sample composition. The % of non-evaporated fragrance material remaining from T = 0 is calculated at each time point for each sample composition. The % fragrance material remaining in each composition is plotted to give an evaporation profile over time. This is done for both the test and control compositions. Significance is determined by comparison of the evaporation profile for the same fragrance material or same fragrance mixture in the test and control compositions. Test Method 4: Analytical Headspace Tests

The following test is carried out to demonstrate the character retention over time of a fragrance composition of the present invention vs. a control. It is necessary for the test and control samples to be run at approximately the same time to ensure that ambient conditions are the same. The test measures the presence of one or more fragrance materials in the headspace formed in a sealed vial by the test composition, after set evaporation times. The fragrance profile in the headspace is measured at specific time points through the use of headspace ("HS") gas chromatography ("GC").

1. The test and control compositions as described in the Example section are used for the evaluation.

2. Capillaries of about 2 cm to 3.5 cm, with one sealed end are cut from a Sigma Aldrich "Stuart™ melting point tube" product code Z673269, or equivalent. A suitable fixed volume chosen between 50 and 200 μΐ _^ of the composition is pipetted into the well of a VWR Tissue Culture 96 F well plate, or equivalent. The sealed end of the glass capillary is dipped into the filled well and left for at least 15 sees to wet the surface of the glass. Care must be taken not to contact the glass capillary with the sides of the well by maintaining it straight and approximately in the center of the well.

3. The glass capillary is then removed from the well and inverted or transferred onto a stable surface or into a holder and allowed to evaporate at ambient conditions for a set period of time. A windshield may be used to reduce high air turbulence.

4. The glass capillary is then introduced into an empty 20 mL HS vial, which is immediately closed with a PTFE cap. The time at which this takes place is determined to be time T = initial (i.e., T = 10 mins).

5. Multiple glass capillaries are prepared in the same way and left to evaporate at ambient temperature for pre-determined periods of time, such as for example 10, 15, 30 mins, 1 hr, 2 hrs, 3 hrs, 4 hrs, 5 hrs, and up to 6 hrs, before being introduced to the headspace vial and sealed.

6. The HS vial is then analysed on an Agilent GC system 6890 equipped with a Gerstel MPS 2 autosampler, or equivalent, capable of performing SPME injections. A SPME fiber assembly DVB/CAR/PDMS (50/30 μιη, 1 cm length) is required. A GC column such as a DB-5MS, ZB-5MSi models, or equivalent phase, with a length of 30 m, an inner diameter of 0.25 mm and a film thickness of 1 μιη is used.

7. The SPME HS parameters are set to the values indicated as follows:

Incubation chamber temperature: 40 °C Incubation time: 20 mins

Agitation of sample 250 RPM

Extraction time 5 mins

Desorption time 2 mins

The GC parameters are set to the values indicated as follows

Gas chromatography with flame ionization detection ("FID") or with mass spectrometry ("MS") can be used for the identification and quantification of fragrance material in the compositions. Either detection system can be used in conjunction with GC. The column dimensions as well as GC settings described in this method, such as injector temperature, carrier gas velocity, temperature ramp and final oven temperature can be adjusted to optimize the response of the fragrance material being monitored. The detection system settings, such as FID gas flows and temperature or MS parameters, should be optimized by a trained analyst to enable the precise detection and identification of the analytes of interest.

A qualitative assessment of the chromatograms obtained is performed by comparing the peak height of the fragrance materials and overall chromatogram at time T = 10 mins to other time points. A dotted line is drawn around an estimated retention time where fragrance materials with a vapour pressure of 0.001 Torr or less (0.000133 kPa or less) elute during the analysis. The difference between the peaks present at each measured time point for the test and control compositions provides evidence of the retention of the character of the fragrance over time.

This test set-up is designed to enable the collection of the headspace in a manner that does not saturate the SPME fiber. If the fiber is saturated it does not provide an accurate analysis of the headspace composition. Therefore the quantity of liquid and the evaporation surface area are very different from those in the olfactive evaluation of the same samples. For this reason it is not possible to compare directly the evaporation time frames used in the 2 experiments. It is expected that the evaporation profile is much faster in this headspace experiments compared to the olfactive evaluations.

EXAMPLES

The following examples are provided to further illustrate the present invention and are not to be construed as limitations of the present invention, as many variations of the present invention are possible without departing from its spirit or scope.

Example 1 - Fragrance Oils

Fragrance examples 1, 2, 3, 4b and 5b are provided below in Tables 6, 7, 8, 9 and 10, respectively, as non-limiting examples of formulations of fragrance materials intended to form the fragrance component of the compositions of the present invention. The exemplary formulations of the fragrance materials span the range from "simple accords" (less than 10 fragrance materials) to "complex fragrances" (greater than 30 fragrance materials). Typically, full bodied fragrance compositions do not comprise less than about 30 fragrance materials.

Fragrance examples 4a and 5a provided in Table 9 and 10, respectively, below are examples of traditional formulations of fragrance materials that fall outside the scope of the present invention.

Fragrance example 6 provided in Table 11 below as an example of a formulation of volatile fragrance materials.

Fragrance examples 7 and 8 are provided in Tables 12 and 13 below as examples of a formulation of fragrance materials intended to form the fragrance component that fall outside the scope of the present invention.

Fragrance examples 9 to 16 are provided in Tables 14 and 15 below as examples of formulations of fragrance materials containing higher than 30 wt% of the low volatile fragrance materials.

Fragrance examples 17 and 18 are provided in Tables 16 and 17 below as comparative samples of formulations of fragrance materials intended to form the fragrance component. The following fragrance formulations are made by mixing the listed ingredients in the listed proportions (wt%) at room temperature, wherein the wt% is relative to the total weight of the fragrance component.

Table 6 - Fragrance Example 1 (Fresh Floral Accord - 10 wt% of Low Volatile Fragrance Materials)

Table 7 - Fragrance Example 2 (Fresh Male Accord - 13.51 wt% of Low Volatile Fragrance Materials)

Supplied at 50% in Isopropyl myristate. Table 8 - Fragrance Example 3 (Sweet Dream 18 Fragrance - 11.15 wt% of Low Volatile Fragrance Materials)

Vapor Pressure Parts

Ingredients CAS Number

(Torr at 25 °C) (wt%)

Prenyl acetate 1191-16-8 3.99000000 0.100

Manzanate 39255-32-8 2.91000000 0.200

Hexyl acetate 142-92-7 1.39000000 0.700 cis-3-Hexenyl

3681-71-8 1.22000000 0.200 acetate

Benzaldehyde 100-52-7 0.97400000 0.200

Liffarome 67633-96-9 0.72100000 0.150

Hexyl isobutyrate 2349-07-7 0.41300000 0.055

Dihydromyrcenol 18479-58-8 0.16600000 2.500

Benzyl acetate 140-11-4 0.16400000 0.700

Linalyl acetate 115-95-7 0.11600000 2.500

Verdox 88-41-5 0.10300000 4.000

Phenethyl alcohol 60-12-8 0.07410000 8.000

Rossitol 215231-33-7 0.02990000 1.500 alpha- Terpineol 98-55-5 0.02830000 1.500

Geranyl acetate 105-87-3 0.02560000 1.500

Rhodinol 141-25-3 0.01970000 0.700

Givescone 57934-97-1 0.01710000 0.700

Methyl anthranilate 134-20-3 0.01580000 0.050

Ys amber K 154171-77-4 0.01470000 1.000 alpha-Ionone 127-41-3 0.01440000 3.000

Citronellyl acetate 150-84-5 0.01370000 0.500 cis-3-hexenyl-cis-3-

61444-38-0 0.01220000 0.200 hexenoate

Cinnamic alcohol 104-54-1 0.01170000 0.100 delta-damascone 57378-68-4 0.01020000 0.200

Citronellyloxyacetal

7492-67-3 0.00967000 0.100 dehyde

Cymal 103-95-7 0.00881000 0.500

Floralozone 67634-15-5 0.00808000 0.100

Ethylmethylphenylg

77-83-8 0.00571000 0.200 lycidate

Floras a Q 63500-71-0 0.00557000 3.000

Ethyl linalool 10339-55-6 0.00520000 6.400

Pivarose 67662-96-8 0.00484000 2.500 Hydroxycitronellal 107-75-5 0.00318000 7.500

Methyl Ionone 7779-30-8 0.00286000 4.000 gamma-

104-67-6 0.00271000 0.500

Undecalactone

Kephalis 36306-87-3 0.00269000 5.000

Cashmeran 33704-61-9 0.00269000 1.000

Magnolan 27606-09-3 0.00251000 3.000

Majantol 103694-68-4 0.00224000 6.900

Brahmanol 72089-08-8 0.00154000 3.000

Coumarin 91-64-5 0.00130000 0.500

Glycolierral 68901-32-6 0.00121000 0.100

Raspberry ketone 5471-51-2 0.00106000 0.100

Top Mango base ^J — — 0.500

Cherry base ^J — — 0.200

Cassis base ^J — — 0.300

Bergamot Oil ⁴ — — 6.000

Prunella base ^J — — 0.500

Hexyl cinnamic

101-86-0 0.00069700 1.500 aldehyde

Sandalore 65113-99-7 0.00062500 3.000

Dupical 30168-23-1 0.00044100 0.005

Galaxolide ^{® 1} 1222-05-5 0.00041400 1.500

Ebanol 67801-20-1 0.00028100 2.000

Helvetolide 141773-73-1 0.00005790 2.000

Warm Milk base ⁵ — -- 0.200

Vanilla Absolute ' ⁶ — — 0.100

Isopropyl Myristate — -- 1.500

Dipropylene Glycol — — 6.040

Total 100.00

Supplied at 50% in IPM.

2 Supplied at 50% in DiPG.

³ Proprietary bases that contain a mixture of perfume raw materials, judged to be of high volatility for the purposes of calculating % of low volatility PRMs.

4 Natural oils or extracts that contain a mixture of perfume raw materials, judged to be of high volatility for the purposes of calculating % of low volatility PRMs.

5 Proprietary bases that contain a mixture of perfume raw materials, judged to be of low volatility for the purposes of calculating % of low volatility PRMs. ⁶ Natural oils or extracts that contain a mixture of perfume raw materials, judged to be of low volatility for the purposes of calculating % of low volatility PRMs.

Table 9 - Fragrance Examples 4a and 4b ("Traditional Floral Magnifica" Example 4a - 37 wt% of Low Volatile Fragrance Materials; 55 wt% of Moderate Volatile Fragrance Materials; 7 wt% of High Volatile Fragrance Materials; and "Diamond Floral Magnifica" Example 4b - 13 wt% of Low Volatile Fragrance Materials; 80 wt% of Moderate Volatile Fragrance Materials; 7 wt% of High Volatile Fragrance Materials)

Parts (wt%)

Vapor Pressure Example 4a Example 4b

Ingredients CAS Number

(Torr at 25 °C) (Traditional) (Diamond)

Beta Gamma

928-96-1 2.126000 0.20 0.20

Hexenol

Cis 3 Hexenyl

3681-71-8 1.219000 0.30 0.30

Acetate

Benzyl Acetate 140-11-4 0.16400000 3.01 3.01

Liffarome 67633-96-9 0.721000 0.20 0.20

Ligustral Or

68039-49-6 0.578000 0.10 0.10

Triplal

Methyl

67674-46-8 0.214000 0.40 0.40

Pamplemousse

d-Limonene 5989-27-5 1.54000000 3.01 3.01

Phenyl

0.368000 0.0002 0.0002

Acetaldehyde ^;

Total High Volatile Fragrance Materials 7.2% 7.2%

Alpha Damascone 24720-09-0 0.008300 0.04 0.06

Ethyl 24-

3025-30-7 0.009540 0.20 0.20

Decadienoate

Ambronat 6790-58-5 0.009340 2.00 2.01 cis-3-Hexenyl cis-

61444-38-0 0.012200 0.10 0.10

3-Hexenoate

Citronellol 106-22-9 0.032900 4.01 4.01

Cyclemax 7775-00-0 0.018200 0.40 0.40

Cyclo Galbanate 68901-15-5 0.003230 0.10 0.10

Cymal 103-95-7 0.008810 0.90 1.51

Dimethyl Benzyl

10094-34-5 0.001680 0.50 0.50

Carbinyl Butyrate

Ethyl 2,4-

3025-30-7 0.00954000 0.20 0.20

Decadienoate

Ethyl Linalool 10339-55-6 0.005200 7.23 12.04

Florol 63500-71-0 0.005570 6.43 10.71

Gamma

706-14-9 0.008520 0.20 0.20

Decalactone

Geraniol 106-24-1 0.013300 3.01 5.02 Geranyl Acetate 105-87-3 0.009760 2.01 2.01

Helional 1205-17-0 0.002700 2.41 4.01

Heliotropin 120-57-0 0.010400 0.20 0.20

Hivernal 173445-65-3 0.00392000 0.20 0.20

Hydroxycitronellal 107-75-5 0.003180 2.41 4.01

Ionone Beta 14901-07-6 0.003080 0.24 0.40

Ionone Gamma

127-51-5 0.002820 1.81 3.01

Methyl

Jasmal 18871-14-2 0.004340 5.02 5.02

Jasmolactone 32764-98-0 0.003550 0.20 0.20

Linalyl Propionate 144-39-8 0.026300 1.20 1.20

Magnolan 690304 27606-09-3 0.002510 3.01 5.02

Majantol 103694-68-4 0.002240 2.41 4.01

Para Hydroxy

5471-51-2 0.001060 0.20 0.20

Phenyl Butanone

Phenyl Ethyl

60-12-8 0.074100 3.01 5.02

Alcohol

Phenyl Hexanol 55066-48-3 0.006370 3.61 6.02

Undecavertol 81782-77-6 0.010700 2.01 2.01

Vanillin 121-33-5 0.001940 0.10 0.10

Total Moderate Volatile Fragrance Materials 55.4% 79.7%

37609-25-9

Ambretone 0.00003310 1.00 1.00

28645-51-4

Ambrettolide 0.00000139 1.00 1.00

Cis 3 -Hexenyl 65405-77-8

0.000246

Salicylate 1.51 0.50

118-58-1

Benzyl salicylate 0.00017500 10.79 1.51

Delta Muscenone 63314-79-4

0.00005650 1.00 1.00

Hedione HC 24851-98-7

0.000710 10.54 3.51

Iso-E Super ^® 54464-57-2

0.00053800 10.54 3.51

Polysantol ^® 107898-54-4

0.00011700 0.50 0.50

Total Low Volatile Fragrance Materials 36.9% 12.5%

Total 100 100

delivered as 1% in DPG.

Table 10 - Fragrance Examples 5a and 5b ("Traditional Muguesia Magnifica" Example 5a - 37 wt% of Low Volatile Fragrance Materials; 54 wt% of Moderate Volatile Fragrance Materials; 9 wt% of High Volatile Fragrance Materials; and "Diamond Muguesia Magnifica" Example 5b - 13 wt% of Low Volatile Fragrance Materials; 76 wt% of Moderate Volatile Fragrance Materials; 11 wt% of High Volatile Fragrance Materials)

Ingredients CAS Number Vapor Pressure Parts (wt%) (Torr at 25 °C) Example 5a Example 5b

(Traditional) (Diamond)

Benzyl Acetate 140-11-4 0.304000 5.86 7.32

Benzyl Alcohol 100-51-6 0.158000 0.10 0.10

Beta Gamma

928-96-1 2.126000 0.40 0.40 Hexenol

Cis 3 Hexenyl

3681-71-8 1.219000 0.20 0.20 Acetate

Linalyl Acetate 115-95-7 0.077400 1.00 1.00

Methyl Phenyl

93-92-5 0.203000 0.32 0.40 Carbinyl Acetate

d-Limonene 5989-27-5 1.54000000 1.00 1.00

Phenyl

Acetaldehyde 101-48-4 0.000538 0.20 0.10 Dimethyl Acetal

Total High Volatile Fragrance Materials 9.1% 10.5%

Cis Jasmone 488-10-8 0.020100 0.50 0.50

Cinnamic Alcohol 104-54-1 0.005720 0.20 0.20

Cinnamic

104-55-2 0.02650000 0.06 0.06 Aldehyde

Citronellol 106-22-9 0.032900 4.01 5.01

Citronellyl

150-84-5 0.013700 3.21 4.01 Acetate

Citronellyl

7492-67-3 0.009670 0.10 0.10 Oxyacetaldehyde

Cyclemax 7775-00-0 0.018200 0.32 0.40

Cyclo Galbanate 68901-15-5 0.003230 0.20 0.20

Cymal 103-95-7 0.008810 1.61 2.01

Ethyl Linalool 10339-55-6 0.005200 8.03 10.03

Florhydral 125109-85-5 0.020700 0.16 0.20

Geraniol 106-24-1 0.013300 4.01 5.02

Geranyl Acetate 105-87-3 0.009760 3.21 4.01

Helional 1205-17-0 0.002700 4.01 5.02

Hydroxycitronellal 107-75-5 0.003180 3.21 4.01

Indol 120-72-9 0.029800 0.10 0.10

Jasmal 18871-14-2 0.004340 3.21 4.01

Majantol 103694-68-4 0.002240 3.21 4.01

Phenyl Ethyl

103-45-7 0.056400 0.40 0.40 Acetate

Phenyl Ethyl

60-12-8 0.074100 14.45 18.06 Alcohol

Florosa Q 63500-71-0 0.005570 0 9.03

Total Mod erate Volatility Fragrance Materials 54.2% 76.4%

Ambrettolide 28645-51-4 0.000001 1.00 1.00

Cis-3-Hexenyl 65405-77-8 0.000246 1.00 0.50 Salicylate

Benzyl Salicylate 118-58-1 0.00017500 16.61 2.51

Hedione ^® He 24851-98-7 0.000710 8.03 4.01

Iso-E Super ^® 54464-57-2 0.000538 10.03 5.02

Total Low Volatile Fragrance Materials 36.7% 13.0%

Total 100 100

Table 11 - Fragrance Example 6 (10 Volatile Fragrance Materials)

Table 12 - Fragrance Example 7 (Fresh Floral GF 6-7 Accord - 40.14 wt% of Low Volatile Fragrance Materials)

Vapor Pressure Parts

Ingredients CAS Number

(Torr at 25 °C) (wt%)

Ligustral or

68039-49-6 0.578000 0.15

Triplal

Benzyl acetate 140-11-4 0.164000 0.31

Verdox 88-41-5 0.103000 5.38

Phenethyl alcohol 60-12-8 0.074100 1.54

Indole 120-72-9 0.029800 0.02

Heliotropin 120-57-0 0.010400 1.23

gamma-

706-14-9 0.008520 0.38

Decalactone

Florol 63500-71-0 0.005570 15.38

Ethyl linalool 10339-55-6 0.005200 26.15 Isoeugenol 97-54-1 0.005190 0.08 alpha-Irone 79-69-6 0.004190 1.54

Vanillin 121-33-5 0.001940 6.15

Dimethyl benzyl

10094-34-5 0.001680 1.54

carbinyl butyrate

Methyl beta-

93-08-3 0.000957 0.77

naphthyl ketone

Methyl

24851-98-7 0.000710 30.60 dihydroj asmonate

Benzyl salicylate 118-58-1 0.000175 7.69

Polys antol 107898-54-4 0.000117 0.77

Lrg 201 4707-47-5 0.000029 0.31

Total 100.00

Table 13 - Fragrance Example 8 (Traditional Floral Accord - 54.00 wt% of Low Volatile

Table 14 - Fragrance Examples 9, 10, 11 and 12 (Traditional Flora Magnifica - Greater than 30 wt% of Low Volatile Fragrance Materials)

Fragrance Fragrance Fragrance Fragrance

Ingredients Example 9 Example 10 Example 11 Example 12 Weight % Weight % Weight % Weight %

Traditional Flora 86.96 83.33 74.07 68.97 Magnifica ^;

Ethylene Brassylate 4.35 4.167 3.704 6.90

Methyl Dihydro

Jasmonate 4.35 8.33 14.82 13.79

Iso E super 4.35 4.167 7.407 10.35

Total 100 100 100 100.00

Wt% Low Volatile

44.33 46.66 52.60 55.87 Fragrance Materials

Wt% Moderate Volatile

49.57 47.50 42.22 39.31 Fragrance Materials

Wt% High Volatile

6.09 5.83 5.18 4.83 Fragrance Materials

Fragrance Example 4a.

Table 15 - Fragrance Examples 13, 14, 15 and 16 (Traditional Muguesia Magnifica - Greater than 30 wt% of Low Volatile Fragrance Materials)

Fragrance Example 5a.

Fragrance example 17 (as disclosed in Table 16) is composed of 30.28 wt% of high volatile fragrance materials, 38.21 wt% of moderate volatile fragrance materials and 31.48 wt% of low volatile fragrance materials, wherein the wt% is relative to the total weight of the fragrance component.

Table 16 - Fragrance Example 17 (Comparative Fragrance 1 - 31.48 wt% of Low Volatile Fragance Materials)

* origin: Firmenich SA (Geneva, Switzerland).

^; Propyl (S)-2-(l,l-dimethylpropxy)propanoate.

² 8-Methoxy-2,6,6,8-tetramethyl-tricyclo[5.3.1.0(l,5)]undecane .

³ 7-Methyl-2H,4H- 1 ,5-benzodioxepin-3-one.

⁴ 1 -(3, 3 -dimethyl- l-cyclohexyl)ethyl formate; origin: International Flavors & Fragrances.

5 Methyl dihydrojasmonate.

⁶ Linalool. Fragrance materials added as dilutions in a non-volatile solvent. For the purpo: calculating the fragrance oil composition actual fragrance materials levels added are used.

Fragrance example 18 (as disclosed in Table 17) is composed of 26.71 wt% of high volatile fragrance materials, 63.88 wt% of moderate volatile fragrance materials and 9.37 wt% of low volatile fragrance materials, wherein the wt% is relative to the total weight of the fragrance component.

Table 17 - Fragrance Example 18 (Comparative Fragrance 2 - 9.37 wt% of Low Volatile Fragance Materials)

Vapor Amount

CAS Pressure

Ingredients Parts by Parts

Number (Torr at 25

Weight (wt%)

°C)

D-Limonene 5989-27-5 1.540 50.00 5.21 cis-3-Hexenol (10% in DPG) ⁴ 928-96-1 1.040 0.5 0.05

Acetophenone (10% in DPG) ⁴ 98-86-2 0.299 1.00 0.10

Methylphenyl Acetate 101-41-7 0.176 10.00 1.04

Dihydromyrcenol 18479-58-8 0.166 50.00 5.21

Benzyl acetate 140-11-4 0.164 60.00 6.25

Tetra-Hydro Linalool n/a 0.115 50.00 5.21 n-Undecanal n/a 0.102 5.00 0.52

Linalool 78-70-6 0.0905 40.00 4.17

Phenylethyl Alcohol 60-12-8 0.0741 245.00 25.53

Allyl amyl glycolate (10% in

67634-00-8 0.04000 2.00 0.21 DPG) ⁴

Indole (10% in DPG) ⁴ 120-72-9 0.02980 1.00 0.10

Alpha-Terpineol 98-55-5 0.02830 30.00 3.13

Diphenyl Oxide 101-84-8 0.02230 5.00 0.52

L-Citronellol 7540-51-4 0.01830 80.00 8.34

Beta-Ionone 14901-07-6 0.01690 5.00 0.52

Alpha-Ionone 127-41-3 0.01440 15.00 1.56

Dimethyl benzyl carbinyl acetate 151-05-3 0.01390 30.00 3.13

Geraniol 106-24-1 0.01330 40.00 4.17

Nerol n/a 0.01330 20.00 2.08

Lilian ¹ 80-54-6 0.00444 60.00 6.25

Gamma- Undecalactone 104-67-6 0.00271 15.00 1.56

Amyl salicylate 2050-08-0 0.00144 25.00 2.61

Galaxolide ^® 1222-05-5 0.000414 20.00 2.08 cis-3-Hexenyl salicylate 65405-77-8 0.000246 20.00 2.08

Ethylene Brassylate 105-95-3 0.00000000313 30.00 3.13

Styrolyl Acetate ⁵ n/a n/a 20.00 2.08 Decenol trans-9 n/a n/a 15.00 1.56

Geranium oil n/a n/a 15.00 1.56

Total 959.5 100 wt%

Benzenepropanal, 4-( 1 , 1 -dimethylethyl)-a- methyl- .

2

Natural oil that is judged to be volatile for the purposes of calculating levels of the volatile fragrance materials.

³ Proprietary oil that is judged to be volatile for the purposes of calculating levels of the volatile fragrance materials.

⁴ Fragrance materials added as dilutions in a non-volatilee solvent. For the purposes of

calculating the fragrance oil composition actual fragrance materials levels added are used.

⁵ Unknown oil that is judged to be of low volatility for the purposes of calculating levels of the volatile fragrance materials.

Example 2 - Compositions Comprising Fragrance Oils and Substantially Non-Odorous Fragrance Modulators

Compositions A1, D1, G1, J1 and Ml are examples of fragrance compositions according to the present invention, made with any one of fragrance examples 1-3, 4b, 5b and 18, respectively. Compositions B, E, H, K and N are examples of fragrance compositions containing any one of the following fragrance examples 4a, 5a, and 7-17, and which are outside the scope of the present invention. In parallel, control compositions CI, Fl, II, LI and 01 are prepared by replacing the different substantially non-odorous fragrance modulators by the same amount of deionized water. All of the compositions are prepared by admixture of the components described in Table 18(a), in the proportions indicated.

Table 18(a) - Fragrance Compositions

Fragrance Composition (wt%) '

Ingredients

< u Q ω 1— 1 i-s - o

Fragrance 5- 0.01 3- 5- 0.1-

- - - - - - - - - - Al ² 10 -2 10 10 5

Fragrance 5- 0.01 3- 5- 0.1-

- - - - - - - - - - B ³ 10 -2 10 10 5

Fragrance 5- 0.01 3- 5- 0.1-

- - - - - - - - - - Al or B 10 -2 10 10 5

Ethanol 60-99.99

Butylated

0-0.07

Hydroxy Toluene

Modulator 2- 2-

A ⁴ 20 20

Modulator

- - - 0.1 0.1

B ⁵

Modulator 0.1- 0.1-

- - - - - -

C ⁶ 5 5

Modulator 2- 2-

- - - - D ⁷ 10 10

Modulator 0.1- 0.1-

-

E ^s 3 3

Deionized

to 100.00

water

Wt% is relative to the total weight of the composition.

Can be any one of fragrance examples 1-3, 4b, 5b, and 18.

3 Can be any one of fragrance examples 4a, 5a, and 7-17.

⁴ Can be any one of the substantially non-odorous fragrance modulators examples: sucrose laurate; sucrose dilaurate, sucrose myristate, sucrose palmitate, sucrose sterate; sucrose distearate; or sucrose tristearate.

⁵ Substantially non-odorous fragrance modulator is (E)-l-(2,2,6-trimethylcyclohexyl)oct-l-en-3- one.

⁶ Can be any one of the substantially non-odorous fragrance modulators examples: 2-(l- menthoxy) ethane- l-ol; l-(l-menthoxy) propane-2-ol; 3-(l-menthoxy) propane-l-ol; 3-(l- menthoxy) propane- 1,2-diol; 2-methyl-3-(l-menthoxy)propane-l,2-diol; or 4-(l -menthoxy) butane- l-ol.

Substantially non-odorous fragrance modulator is Hydroquinone beta-D-glycoside.

Substantially non-odorous fragrance modulator is Hyaluronic acid disaccharide sodium salt or Sodium Hyaluronate (20-50 kDa).

Compositions A2, D2, G2, J2 and M2 are examples of fine fragrance compositions according to the present invention, made with any of the fragrance examples 1 to 3, 4b, 5b, and 18 respectively. Compositions B2, E2, H2, K2 and N2 are examples of fragrance compositions containing traditional or higher levels of low volatile fragrance materials, made with any of the fragrance examples 4a, 5a, and 7-17, respectively. In parallel, control compositions C2, F2, 12, L2 and 02 are prepared by replacing the different substantially non-odorous fragrance modulators by the same amount of deionized water. All of the compositions are prepared by admixture of the components described in Table 18(b), in the proportions indicated.

Table 18(b) - Fragrance Compositions

Wt% is relative to the total weight of the composition.

2

Can be any one of fragrance examples 1-3, 4b, 5b, and 18.

³ Can be any one of fragrance examples 4a, 5a, and 7-17.

⁴ Can be any one of the substantially non-odorous fragrance modulators examples: Propylene Glycol Propyl Ether, Hexaethylene glycol monododecyl ether, Panthenol Ethyl Ether, DL- Panthenol , Diisobutyl Adipate, or Diisoamyl Adipate.

5 Neopentyl Glycol Diisononanoate.

⁶ 2-ethylhexyloxypropanediol.

⁷ PPG- 11 Stearyl Ether. Can be any one of the substantially non-odorous fragrance modulators examples: Dicetyl Ether; Polyglycerin-4 Ethers; Isoceteth-5; Isoceteth-7, Isoceteth-10; Iscoeteth-12; Isoceteth-15; Isoceteth-20; Isoceteth-25; Isoceteth-30; Disodium Lauroamphodipropionate; Hexaethylene glycol monododecyl ether; or Cetearyl Ethylhexnoate.

Composition A3 is an example of a fragrance composition according to the present invention, made with any of the fragrance examples 1-3, 4b, 5b and 18, respectively. Composition B3 is an example of a fragrance composition containing traditional or higher levels of low volatile fragrance materials, made with any of the fragrance examples 4a, 5a, and 7-17, respectively. In parallel, a control composition C3 is prepared by replacing the different substantially non-odorous fragrance fixative by the same amount of deionized water. All of the compositions are prepared by admixture of the components described in Table 18(c) in the proportions indicated.

Table 18(c) - Fragrance Composition

Wt% is relative to the total weight of the composition.

2

Can be any one of fragrance examples 1-3, 4b, 5b, and 18.

³ Can be any one of fragrance examples 4a, 5a, and 7-17.

⁴ Can be any one of the substantially non-odorous fragrance modulator as disclosed in Table 4(b).

Compositions A4, D4, G4, and J4 are examples of fragrance compositions according to the present invention, made with any one of fragrance examples 1-3, 4b, 5b, and 18, respectively. Compositions B4, E4, H4, and K4 are examples of fragrance compositions containing any one of the following fragrance examples 4a, 5a, and 7-17, and which are outside the scope of the present invention. In parallel, control compositions C4, F4, 14, and L4 are prepared by replacing the different substantially non-odorous fragrance modulators by the same amount of deionized water or ethanol. All of the compositions are prepared by admixture of the components described in Table 18(d), in the proportions indicated.

Table 18(d) - Fragrance Compositions

Wt% is relative to the total weight of the composition.

2

Can be any one of fragrance examples 1-3, 4b, 5b, and 18.

³ Can be any one of fragrance examples 4a, 5a, and 7-17.

⁴ Available as GLUCAM™ P-20.

⁵ Available as Plantacare ^® 810 UP.

β Available as Simulsol ^® SL 11W.

7 Available as Ceraphyl ^® ICA.

Compositions A5 is an example of a fragrance composition according to the present invention, made with any one of fragrance examples 1-3, 4b, 5b, and 18, respectively. Compositions C5 is an example of a fragrance composition containing traditional or higher levels of low volatile fragrance materials, made with any one of the following fragrance examples 4a, 5a, and 7-17, respectively. In parallel, control compositions C5 is prepared by replacing the different substantially non-odorous fragrance modulator by the same amount of deionized water. All of the compositions are prepared by admixture of the components described in Table 18(e), in the proportions indicated.

Table 18(e) - Fragrance Composition

Wt% is relative to the total weight of the composition.

2

Can be any one of fragrance examples 1-3, 4b, 5b, and 18.

3 Can be any one of fragrance examples 4a, 5a, and 7-17.

⁴ Can be any one of the substantially non-odorous fragrance modulators nos. 1, 3, 7, 8, 99, 100, and 101-103 as disclosed in Table 4(a).

Tables 19(a) provides test compositions (MODI to MOD3) comprising the volatile fragrance formulation of fragrance example 6 (as disclosed in Table 11) with a substantially non- odorous fragrance modulator (as disclosed in Tables 4(a) and 4(b)) that are particularly suited to analytical measurements. All of the compositions are prepared by admixture of the components described in Table 19(a) in the proportions indicated.

Table 19(a) - Fragrance Example (Compositions Comprising 10 Volatile Fragrance Materials)

Test composition Reference composition

(wt% ² ) (wt% ² )

Ingredients

MOD 1 to 3 REF

Fragrance A 7.0 7.0

Triethyl citrate 0.25 to 1.0 0.25 to 1.0 Ethanol 75.0 75.0

Modulator ³ 15.0 0.0

Water qsp qsp

Total 100.0 100.0

^; Wt% is relative to the total weight of the composition.

Fragrance Example 6 (as disclosed in Table 11).

3 Can be any one of the substantially non-odorous fragrance modulator nos. 7, 8 and 100 as disclosed in Table 4(a).

Tables 19(b) provides test compositions comprising the volatile fragrance formulation of fragrance example 6 (as disclosed in Table 11) with a substantially non-odorous fragrance modulator (as disclosed in Tables 4(a) and 4(b)) that are particularly suited to analytical measurements. All of the compositions are prepared by admixture of the components described in Table 19(b) in the proportions indicated.

Table 19(b) - Compositions comprising fragrance with 10 Volatile Fragrance Materials

Wt% is relative to the total weight of the composition.

Fragrance Example 6 (as disclosed in Table 11).

³ Can be any one of the substantially non-odorous fragrance modulator nos. 1-6, 9-99, and 101- 103 as disclosed in Table 4(a) and substantially non-odorous fragrance modulator nos. 1-189 as disclosed in Table 4(b).

Example 3 - Single Fragrance Material Compositions containing Substantially Non-Odorous Fragrance Modulators Compositions A6, C6, E6, and G6-L6 are examples of compositions according to the present invention, made with single fragrance materials and the substantially non-odorous fragrance modulators, respectively. In parallel, control Compositions B6, D6, F6 and M6 are prepared without a substantially non-odorous fragrance modulator as a control. All the compositions are prepared by admixture of the components in Table 20, in the proportions indicated.

Table 20 - Single Fragrance Material Compositions

Wt% is relative to the total weight of the composition.

2

Can be any one of the substantially non-odorous modulators examples: sucrose laurate, sucrose dilaurate, sucrose palmitate, sucrose stearate, sucrose distearate, or sucrose tristearate.

³ Can be any one of the substantially non-odorous modulators examples: (E)- 1 -(2,2,6- trimethylcyclohexyl)oct-l-en-3-one.

⁴ Can be any one of the substantially non-odorous modulators examples: 2-(l-menthoxy) ethane- l-ol; l-(l-menthoxy) propane-2-ol; 3-(l-menthoxy) propane-l-ol; 3-(l-menthoxy) propane-1,2- diol; 2-methyl-3-(l-menthoxy)propane-l,2-diol; or 4-(l-menthoxy) butane-l-ol. Substantially non-odorous fragrance modulator is Hydroquinone beta-D-glycoside (available as Arbutin from Sigma- Aldrich).

⁶ Can be any one of the single fragrance materials: Dimethyl Benzyl Carbinol; Ethyl Safranate, Phenyl ethyl alcohol or Eugenol.

Substantially non-odorous fragrance modulator is Hyaluronic acid disaccharide sodium salt or Sodium Hyaluronate (20-50 kDa).

Compositions A7, C7 and E7-I7 are examples of compositions according to the present invention, made with single fragrance materials and the substantially non-odorous fragrance modulators, respectively. In parallel, control Compositions B7, D7 and J7 are prepared without a substantially non-odorous fragrance modulator as a control. All the compositions are prepared by admixture of the components in Table 21, in the proportions indicated.

Table 21 - Single Fragrance Material Compositions

Wt% is relative to the total weight of the composition.

2

Can be any one of the substantially non-odorous modulators examples: Hexaethylene glycol monododecyl ether, Panthenol Ethyl Ether, DL-Panthenol, or Diisoamyl Adipate.

3 Neopentyl Glycol Diisononanoate. ⁴ 2-ethylhexyloxypropanediol.

⁵ PPG- 11 Stearyl Ether.

⁶ Can be any one of the single fragrance materials examples: Dimethyl Benzyl Carbinyl Acetate or Eugenol.

Can be any one of the substantially non-odorous modulators examples: Dicetyl Ether; Polyglycerin-4 Ethers; Isoceteth-5; Isoceteth-7, Isoceteth-10; Isoceteth-12; Isoceteth-15; Isoceteth-20; Isoceteth-25; Isoceteth-30; Disodium Lauroamphodipropionate; Hexaethylene glycol monododecyl ether or Cetearyl Ethylhexnoate.

Compositions A8, C8, E8, G8, 18, K8, M8, Q8, S8, U8, W8, Y8, AA8, and CC8 are examples of compositions according to the present invention, made with single fragrance materials and the substantially non-odorous fragrance fixatives, respectively. In parallel, control Compositions B8, D8, F8, H8, J8, L8, N8, P8, R8, T8, V8, X8, Z8, BB8, and DD8 are prepared without a substantially non-odorous fragrance fixative as a control. All of the compositions are prepared by admixture of the components in Tables 22(a) and 22(b), in the proportions indicated. Table 22(a) - Single Fragrance Material Compositions

Wt% is relative to the total weight of the composition.

Can be any one of the single fragrance materials of Table 2 or 3.

Table 22(b) - Single Fragrance Material Compositions

Wt s re at ve to t e tota we g t o t e compos t on.

Compositions A9, C9, E9, G9 and 19 are examples of compositions according to the present invention, made with single fragrance materials and the substantially non-odorous fragrance modulators, respectively. In parallel, control Compositions B9, D9, F9, H9 and J9 are prepared without a substantially non-odorous fragrance modulator as a control. All the compositions are prepared by admixture of the components in Table 22(c), in the proportions indicated.

Table 22(c) - Single Fragrance Material Compositions

Single Fragrance Material Composition (wt%) ¹

Ingredients

A9 B9 C9 D9 E9 F9 G9 H9 19 J9

Indocolore 1.0 1.0 - - - - - - - -

Dimethyl Benzyl

- - 1.0 1.0 - - - - - - Carbinol

Eugenol - - - - 1.0 1.0 - - - -

Phenylethyl - - - - - -

- - 1.0 1.0

alcohol

Fragrance C - - - - - - - - 1.0 1.0

Expert Gel ^®

5.0 0.0 - - - - - - - - EG56 ³

Kolliphor ^® EL ⁴ - - 16.6 0.0 15.2 0.0 13.0 0.0 - -

Glycerol

- - - - - - - - 0.1-20 0.0 Alkxoylates ⁵

Ethanol to 100 ^; Wt% is relative to the total weight of the composition.

Can be any one of the single fragrance materials examples: Indocolore, Dimethyl Benzyl Carbinol, Eugenol or Phenethyl alcohol.

³ Chemical name is Bis-methoxy PEG-13 PEG-438/PPG-110 SMDI Copolymer and listed as a substantially non-odorous modulator no. 99 as disclosed in Table 4(a).

⁴ Chemical name is propyl {4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl}acetate and listed as a substantially non-odorous modulator no.100 as disclosed in Table 4(a).

⁵ Can be any one of the substantially non-odorous modulators examples: 3-((2- ethylhexyl)oxy)propane-l,2-diol (modulator no. 101 as disclosed in Table 4(a)); 3-((2- propylheptyl)oxy)propane-l,2-diol (modulator no. 102 as disclosed in Table 4(a)); or l-amino-3- ((2-ethylhexyl)oxy)propan-2-ol (modulator no. 103 as disclosed in Table 4(a)).

Composition A10 is an example of a composition according to the present invention, made with single fragrance material and the substantially non-odorous fragrance modulator, respectively. In parallel, control Composition B10 is prepared without a substantially non- odorous fragrance modulator. All the compositions are prepared by admixture of the components in Table 22(d), in the proportions indicated.

Table 22(d) - Single Fragrance Material Compositions

Wt% is relative to the total weight of the composition.

Can be any one of the fragrance materials disclosed in Tables 2 and 3.

3 Can be any one of the substantially non-odorous fragrance modulator not already disclosed in Tables 20, 21, and 22(a)-22(c) above.

Example 4 - Exemplary Product Compositions

Compositions I, II, III and rV are examples of body spray compositions according to the present invention. They are prepared by admixture of the components described in Table 23, in the proportions indicated. Table 23 - Body Spray Compositions

wt% relative to the total weight of the composition.

2

Can be any one of Fragrances Examples 1, 2, 3, 4b, 5b or 18.

³ Can be any one of the substantially non-odorous fragrance modulators disclosed in Tables 4(a) and 4(b).

Composition V, VI and VII are examples of body lotion compositions according to the present invention. They are prepared by admixture of the components as described in Table 24, in the proportions indicated.

Table 24 - Body Lotion Composition

Com positions (wt% )

Ingredients CAS Number

V VI VII

Water 7732-18-5 qsp 100 % qsp 100 % qsp 100 %

Trilon ^® B 64-02-8 0.05 0.05 0.05

Carbopol ^® ETD 2050 9003-01-4 0.2 0.2 0.2

Pemulen™ TR1 9063-87-0 0.2 0.2 0.2

Nexbase ^® 2008 68037-01-4 8 8 8

Silicone V100 63148-62-9 6 6 6

Fragrance Modulator ³ — 3 3 3

Tris Amino™ Ultra Pur 102-71-6 0.4 0.4 0.4

Fragrance — 3 3 3

Preservatives — qs qs qs

Total 100.00 100.00 100.00 ^; wt% relative to the total weight of the composition.

Can be any one of the Fragrances Examples 1, 2, 3, 4b, 5b or 18.

3 Can be any one of the substantially non-odorous fragrance modulators disclosed in Tables 4(a) and 4(b).

Example 5 - Qlfactive Test Results

Compositions disclosed in Tables 18(a)- 18(d), 20, 21, and 22(a)-22(d) are applied to glass slides in accordance with the protocol described in the Method Section and a panel of 6-10 experienced panelists evaluate the perceived fragrance profile at initial time 0, then at various time points, typically 1 hour, 2 hours, 3 hours, 4 hours and 6 hours post application. Panelists are asked to score the compositions for the longevity and/or fidelity of the fragrance profile on a scale of 0 to 5, wherein 0 represents a no fragrance is detected and 5 represents a very strong fragrance intensity is detected. The results of the panelists are then averaged and discussed below. (a) Efffects of the Substantially Non-Odorous Fragrance Modulators on Single Fragrance

Material Compositions

Figure 2 shows the fragrance intensity profile of Composition A9 (as disclosed in Table 22(c)) as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance modulator Bis-methoxy PEG-13 PEG-438/PPG-110 SMDI Copolymer (i.e., Expert Gel ^® 56) and the single fragrance material Indocolore. Addition of the substantially non-odorous fragrance modulator (Expert Gel ^® 56) maintains the intensity of the fragrance material for up to at least 6 hours whilst the control, Composition B9, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile much more over this time. The substantially non-odorous fragrance modulator acts to maintain the continued initial evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1, 3 and 6 hours (p < 0.0001) at 95% significance level (i.e., p < 0.05) at all these time points.

Figure 3 shows the fragrance intensity profile of Composition C9 (as disclosed in Table 22(c)) as evaluated by 9 panelists, which comprises the substantially non-odorous fragrance modulator propyl {4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl}acetate (i.e., Kolliphor ^® EL) and the single fragrance material Dimethyl Benzyl Carbinol. Addition of the substantially non-odorous fragrance modulator (Kolliphor ^® EL) maintains the intensity of the fragrance material for up to at least 6 hours whilst the control, Composition D9, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile much more over this time. The substantially non-odorous fragrance modulator acts to maintain the reduced rate of evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p < 0.0001), 3 hours (p = 0.0265) and 6 hours (p = 0.0388) at 95% significance level (i.e., p < 0.05) at all these time points.

Figure 4 shows the fragrance intensity profile of Composition E9 (as disclosed in Table

22(c)) as evaluated by 9 panelists, which comprises the substantially non-odorous fragrance modulator propyl {4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl}acetate (i.e., Kolliphor ^® EL) and the single fragrance material Eugenol. Addition of the substantially non-odorous fragrance modulator (Kolliphor ^® EL) maintains the intensity of the fragrance material for up to at least 6 hours whilst the control, Composition F9, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile much more over this time. The substantially non-odorous fragrance modulator acts to supress the initial display of Eugenol and then maintains that continued initial evaporation over time. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 0 hours (p = 0.0025), 1 hour (p < 0.0001), 3 hours (p < 0.0001) and 6 hours (p < 0.0001) at 95% significance level (i.e., p < 0.05) at all time points.

Figure 5 shows the fragrance intensity profile of Composition G9 (as disclosed in Table 22(c)) as evaluated by 9 panelists, which comprises the substantially non-odorous fragrance modulator propyl {4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl}acetate (i.e., Kolliphor ^® EL) and the single fragrance material Phenethyl alcohol (PEA). Addition of the substantially non-odorous fragrance modulator (Kolliphor ^® EL) maintains the intensity of the fragrance material from 1 hour to 3 hours whilst the control, Composition H9, in the absence of the substantially non-odorous fragrance modulator, drops in fragrance intensity profile over this time. The substantially non-odorous fragrance modulator acts to maintain the reduced rate of evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p < 0.0001) at 95% significance level (i.e., p < 0.05) and at 3 hours (p = 0.0876) at 90% significance level (i.e., p < 0.1).

(b) Effects of the Substantially Non-Odorous Fragrance Modulators on the Fragrance Profile Longevity of Compositions having Diamond Construction of Fragrance Component vs. Compositions having Traditional Levels of Fragrance Component (Greater than 30 wt% relative to the total weight of the Fragrance Component) and No Substantially Non-Odorous Fragrance Modulator

Panelists are asked to score the compositions for the intensity of the fragrance on a scale of 0 to 5, wherein 0 represents a no fragrance intensity is detected and 5 represents a very strong fragrance intensity is detected. The results of the panel test are then averaged. The results show the effect of the substantially non-odorous fragrance modulator and diamond constructed fragrance materials for any one of the inventive Compositions Al, A2, A3, A4, A5, Dl, D2, D4, Gl, G2, G4, Jl, J2, J4, Ml, and M2 on fragrance profile longevity versus control Compositions CI, C2, C3, C4, C5, Fl, F2, F4, II, 12, 14, LI, L2, L4, 01, and 02 in the absence of the substantially non-odorous modulator. Alternatively, the results show the effect of the substantially non-odorous fragrance modulator and diamond constructed fragrance materials for any one of the inventive Compositions Al, A2, A3, A4, A5, Dl, D2, D4, Gl, G2, G4, Jl, J2, J4, Ml, and M2 on fragrance profile longevity versus traditional Compositions Bl, B2, B3, B4, B5, El, E2, E4, HI, H2, H4, Kl, K2, K4, Nl, and N2 in the presence of the substantially non- odorous fragrance modulator. Fragrance profile longevity, particularly intensity of the characters attributable to the volatile fragrance materials are maintained for up to at least 6 hours in the presence of the substantially non-odorous fragrance modulator whilst it drops in the absence of the substantially non-odorous fragrance modulator.

Figure 6 provides the fragrance intensity profile of Composition A4 (as disclosed in Table 18(d)), which comprises the substantially non-odorous fragrance modulator PPG-20 Methyl Glucose Ether (i.e., Glucam™ P-20) and the Diamond Floral Magnifica Fragrance Example 4b. Addition of the substantially non-odorous fragrance modulator Glucam™ P-20 maintains the intensity of the fragrance material for up to 6 hours. As compared to the control Composition C4, in the absence of the substantially non-odorous fragrance modulator Glucam™ P-20, and comprising the Traditional Floral Magnifica Fragrance Example 4a drops in fragrance intensity over the 6 hours.

Figure 7 provides the fragrance intensity profile of Composition A4 (as disclosed in Table 18(d)), which comprises the substantially non-odorous fragrance modulator PPG-20 Methyl Glucose Ether (i.e., Glucam™ P-20) and the Diamond Muguesia Magnifica Fragrance Example 5b. Addition of the substantially non-odorous fragrance modulator Glucam™ P-20 maintains the intensity of the fragrance material for up to 6 hours. As compared to the control Composition C4, in the absence of the substantially non-odorous fragrance modulator Glucam™ P-20, and comprising the Traditional Muguesia Magnifica Fragrance Example 5a drops in fragrance intensity over the 6 hours.

Figure 8 provides the fragrance intensity profile of Composition A2 (as disclosed in Table 18(b)), which comprises 15 wt% substantially non-odorous fragrance modulator Diisobutyl Adipate and 7 wt% Diamond Floral Magnifica Fragrance Example 4b. Addition of the substantially non-odorous fragrance modulator Diisobutyl Adipate maintains the intensity of the fragrance material for up to 6 hours. As compared to the control Composition C2, in the absence of the substantially non-odorous fragrance modulator Diisobutyl Adipate, and comprising 7 wt% Traditional Floral Magnifica Fragrance Example 4a drops in fragrance intensity over the 6 hours.

Figure 9 provides the fragrance intensity profile of Composition A2 (as disclosed in Table 18(b)), which comprises 15 wt% substantially non-odorous fragrance modulator Diisobutyl Adipate and 7 wt% Diamond Muguesia Magnifica Fragrance Example 5b. Addition of the substantially non-odorous fragrance modulator Diisobutyl Adipate maintains the intensity of the fragrance material for up to 6 hours. As compared to the control Composition C2, in the absence of the substantially non-odorous fragrance modulator Diisobutyl Adipate, and comprising 7 wt% Traditional Muguesia Magnifica Fragrance Example 5a drops in fragrance intensity over the 6 hours.

Panelists are also asked to score the Compositions Bl, B2, B3, B4, B5, El, E2, E4, HI, H2, H4, Kl, K2, K4, Nl, and N2 for the intensity of the fragrance profile. The results show the effect of the substantially non-odorous fragrance modulator and excessive levels of low volatile fragrance materials for any one of Compositions Bl, B2, B3, B4, B5, El, E2, E4, HI, H2, H4, Kl, K2, K4, Nl, and N2 on fragrance profile longevity and fidelity. Two outcomes are observed: (i) either the fragrance profile longevity is unaffected by the addition of the substantially non- odorous fragrance modulator or (ii) the fragrance profile appears to be suppressed with a loss of strength (data not shown).

Without wishing to be bound by theory, it is believed that the substantially non-odorous fragrance modulator acts to maintain the continued evaporation over time of the fragrance materials, particular the volatile fragrance materials. The effects of the improved fragrance profile longevity of the present invention are noticeable at, any one of, 1, 3 and 6 hours post application.

(c) Effects of the Substantially Non-Odorous Fragrance Modulators on the Fragrance Profile Fidelity of Compositions having Diamond Fragrance Materials (between 10 wt% to 30 wt% relative to the total weight of the Fragrance Component) vs. Compositions having Traditional Levels of Low Volatile Fragrance Materials (Greater than 30 wt% relative to the total weight of the Fragrance Component) and No Substantially Non-Odorous Fragrance Modulator

Panelists are are also asked to score the composition for the fragrance profile fidelity. In particular, the panelists are asked to score the dominance of the floral character attributable to the volatile fragrance materials on a scale of 0 to 3 wherein 0 represents not detectable and 3 represents it being the dominant character. The results of the panel test are then averaged. The results show the effect of the substantially non-odorous fragrance modulator and diamond fragrance materials for the inventive Compositions Al, A2, A3, A4, A5, Dl, D2, D4, Gl, G2, G4, Jl, J2, J4, Ml, and M2 on the floral character dominance versus control Compositions CI, C2, C3, C4, C5, Fl, F2, F4, II, 12, 14, LI, L2, L4, 01, and 02 in the absence of the substantially non-odorous fragrance modulator. Alternatively, the results show the effect of the substantially non-odorous fragrance modulator and diamond fragrance materials for any one of the inventive Compositions Al, A2, A3, A4, A5, Dl, D2, D4, Gl, G2, G4, Jl, J2, J4, Ml, and M2 on fragrance profile fidelity versus traditional Compositions Bl, B2, B3, B4, B5, El, E2, E4, HI, H2, H4, Kl, K2, K4, Nl, and N2 in the presence of the substantially non-odorous fragrance modulator. Fragrance profile fidelity, particularly floral character attributable to the volatile fragrance materials, are maintained by the substantially non-odorous fragrance modulator over time for up to 6 hours in the presence of the substantially non-odorous fragrance modulator whilst it drops in the absence of the substantially non-odorous fragrance modulator.

Figure 10 provides the fragrance fidelity profile of Composition A4 (as disclosed in Table 18(d)), which comprises the substantially non-odorous fragrance modulator PPG-20 Methyl Glucose Ether (i.e., Glucam™ P-20) and the Diamond Floral Magnifica Fragrance Example 4b. Addition of the substantially non-odorous fragrance modulator Glucam™ P-20 maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition C4 comprising the Traditional Floral Magnifica Fragrance Example 4a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator Glucam™ P-20 to Composition B4 comprising Traditional Floral Magnifica Fragrance Example 4a does not result in improved fidelity of the floral character (data not shown).

Figure 11 provides the fragrance fidelity profile of Composition A4 (as disclosed in Table 18(d)), which comprises the substantially non-odorous fragrance modulator PPG-20 Methyl Glucose Ether (i.e., Glucam™ P-20) and the Diamond Muguesia Magnifica Fragrance Example 5b. Addition of the substantially non-odorous fragrance modulator Glucam™ P-20 maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition C4 comprising the Traditional Muguesia Magnifica Fragrance Example 5a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator Glucam™ P-20 to Composition B4 comprising Traditional Muguesia Magnifica Fragrance Example 5a does not result in improved fidelity of the floral character (data not shown).

Figure 12 provides the fragrance fidelity profile of Composition D4 (as disclosed in Table 18(d)), which comprises the substantially non-odorous fragrance modulator Caprylyl/Capryl Glucoside (i.e., Plantacare ^® 810 UP) and the Diamond Floral Magnifica Fragrance Example 4b. Addition of the substantially non-odorous fragrance modulator Plantacare ^® 810 UP maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition F4 comprising the Traditional Floral Magnifica Fragrance Example 4a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator Plantacare ^® 810 UP to Composition E4 comprising Traditional Floral Magnifica Fragrance Example 4a does not result in improved fidelity of the floral character (data not shown).

Figure 13 provides the fragrance fidelity profile of Composition G4 (as disclosed in Table 18(d)), which comprises the substantially non-odorous fragrance modulator Undecyl Glucoside (i.e., Simulsol ^® SL 11W) and the Diamond Floral Magnifica Fragrance Example 4b. Addition of the substantially non-odorous fragrance modulator Simulsol ^® SL 11W maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition 14 comprising the Traditional Floral Magnifica Fragrance Example 4a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator Simulsol ^® SL 11W to Composition H4 comprising Traditional Floral Magnifica Fragrance Example 4a does not result in improved fidelity of the floral character (data not shown).

Figure 14 provides the fragrance fidelity profile of Composition J4 (as disclosed in Table 18(d)), which comprises the substantially non-odorous fragrance modulator Isocetyl Aclohol (i.e., Ceraphyl ^® ICA) and the Diamond Floral Mangifica Fragrance Example 4b. Addition of the substantially non-odorous fragrance modulator Ceraphyl ^® ICA maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition L4 comprising the Traditional Floral Magnifica Fragrance Example 4a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator Ceraphyl ^® ICA to Composition K4 comprising the Traditional Floral Magnifica Fragrance Example 4a does not result in improved fidelity of the floral character (data not shown).

Figure 15 provides the fragrance fidelity profile of Composition A2 (as disclosed in Table 18(b)), which comprises 15 wt% substantially non-odorous fragrance modulator Diisobutyl Adipate and 7 wt% Diamond Floral Magnifica Fragrance Example 4b. Addition of the substantially non-odorous fragrance modulator Diisobutyl Adipate maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition C2 comprising 7 wt% Traditional Floral Magnifica Fragrance Example 4a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator Diisobutyl Adipate to Composition B2 comprising 7 wt% Traditional Floral Magnifica Fragrance Example 4a does not result in improved fidelity of the floral character (data not shown).

Figure 16 provides the fragrance fidelity profile of Composition A2 (as disclosed in Table 18(b)), which comprises 15 wt% substantially non-odorous fragrance modulator Diisobutyl Adipate and 7 wt% Diamond Muguesia Magnifica Fragrance Example 5b. Addition of the substantially non-odorous fragrance modulator Diisobutyl Adipate maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition C2 comprising 7 wt% Traditional Muguesia Magnifica Fragrance Example 5a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator Diisobutyl Adipate to Composition B2 comprising 7 wt% Traditional Muguesia Magnifica Fragrance Example 5a does not result in improved fidelity of the floral character (data not shown).

Figure 17 provides the fragrance fidelity profile of Composition J2 (as disclosed in Table 18(b)), which comprises 15 wt% substantially non-odorous fragrance modulator PPG-11 Stearyl Ether and 7 wt% Diamond Floral Magnifica Fragrance Example 4b. Addition of the substantially non-odorous fragrance modulator PPG-11 Stearyl Ether maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition L2 comprising 7 wt% Traditional Floral Magnifica Fragrance Example 4a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator PPG-11 Stearyl Ether to Composition K2 comprising 7 wt% Traditional Floral Magnifica Fragrance Example 4a does not result in improved fidelity of the floral character (data not shown).

Figure 18 provides the fragrance fidelity profile of Composition J2 (as disclosed in Table 18(b)), which comprises 15 wt% substantially non-odorous fragrance modulator PPG-11 Stearyl Ether and 7 wt% Diamond Muguesia Magnifica Fragrance Example 5b. Addition of the substantially non-odorous fragrance modulator PPG-11 Stearyl Ether maintains the overwhelmingly dominate floral character for up to 6 hours. It is observed for Composition L2 comprising 7 wt% Traditional Muguesia Magnifica Fragrance Example 5a and no modulator, the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator PPG-11 Stearyl Ether to Composition K2 comprising 7 wt% Traditional Muguesia Magnifica Fragrance Example 5a does not result in improved fidelity of the floral character (data not shown).

Panelists are also asked to score the Compositions Bl, B2, B3, B4, B5, El, E2, E4, HI, H2, H4, Kl, K2, K4, Nl, and N2 for the dominance of the floral character. The results show the effect of the substantially non-odorous fragrance modulator and excessive levels of low volatile fragrance materials for any one of Compositions Bl, B2, B3, B4, B5, El, E2, E4, HI, H2, H4, Kl, K2, K4, Nl, and N2 on fidelity of the floral character attributable to the volatile fragrance materials. It is observed that the floral character is perceived initially but then drops quickly over time. Addition of the substantially non-odorous fragrance modulator does not result in improved fidelity of the floral character as seen in any one of Compositions Bl, B2, B3, B4, B5, El, E2, E4, HI, H2, H4, Kl, K2, K4, Nl, and N2 (data not shown).

Panelists are further asked to score the compositions on a scale of 1 to 5, wherein 1 represents the fragrance profile remains unchanged and 5 represents a total change in the fragrance profile versus a control. The results of the panel test are averaged and plotted together with the confidence intervals. The results show the effect of the substantially non-odorous fragrance modulator and diamond fragrance materials for Compositions Al, A2, A3, A4, A5, Dl, D2, D4, Gl, G2, G4, Jl, J2, J4, Ml, and M2. The presence of the substantially non-odorous fragrance modulator and diamond fragrance materials result in noticeable fidelity in fragrance characters. Particularly, noticeable fidelity in the floral aroms attributable to the volatile fragrance materials (data not shown).

Example 6 - Analytical Evaporation Test Results

Using the analytical evaporation Test Method 3, it is possible to measure the amount of each component of a perfume mixture that remains as the fragrance mixture evaporates. Test compositions (MODI to MOD3) comprising a mixture of 10 volatile perfume materials, as disclosed in Table 11 (Fragrance Example 6), and a substantially non-odorous fragrance modulators, as disclosed in Tables 4(a) and 4(b), are introduced in the aluminum containers at the set temperature for pre-determined periods of time in accordance with the protocol described in Test Method 3. Indole is one of the components of the 10 PRMs mixture of Table 11. Control compositions containing the full 10 PRMs mixture as disclosed in Table 11 without the substantially non-odorous fragrance modulator are run alongside the test compositions. The average profile for the control composition is plotted against the individual profile for the indole component from the test composition containing the 10 PRMs mixture of Table 11 with the substantially non-odorous fragrance modulators. The error associated with the method is determined by running replicate evaporation experiments on the control composition. An average evaporation profile of the control composition as well as the 95% confidence interval at each time point are calculated from the replicates.

It is useful to consider the difference (Δ) in the % of remaining fragrance material between each of the test composition (MOD) and their respective control composition (REF) at each experimental time points (e.g., 30 mins, 60 mins and 180 mins) to determine the effect of the substantially non-odorous fragrance modulator on the volatile PRMs in a mixture. The difference (Δ) in the % of remaining of a given fragrance material is calculated as follows:

Δ = % remaining of given fragrance material in test composition (MOD) - % remaining of same fragrance material in control composition (REF)

The difference (Δ) can then be plotted (data not shown) for each of the perfume materials in the mixture at each of the time points. For ease of reference, the applicant has summarize the effect of the substantially non-odorous fragrance modulator on only one volatile fragrance component (e.g., indole) of the mixture, to serve as a representative of all of the volatile fragrance materials. (a) Effect of PPG-3 Myristyl Ether on Compositions having Volatile Fragrance Materials

Figure 19 shows the effect of the substantially non-odorous fragrance modulator PPG-3 Myristyl Ether (i.e., available as Tegosoft ^® APM/ Modulator 7 from Table 4(a)) on the evaporation profile for a representative component (i.e., indole) of the test composition (MODI). With reference to Figure 19, PPG-3 Myristyl Ether has a difference (Δ) of 12 % after 30 mins, 22 % after 60 mins, and 60 % after 3 hours. Addition of the PPG-3 Myristyl Ether in the test composition (MODI) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of PPG-3 Myristyl Ether, drops in fragrance concentration over the 3 hours. Thus, PPG-3 Myristyl Ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown). (b) Effect of Neopentyl Glycol Diethylhexanoate on Compositions having Volatile Fragrance Materials

Figure 20 shows the effect of the substantially non-odorous fragrance modulator Neopentyl Glycol Diethylhexanoate (i.e., available as Schercemol™ NGDO/ Modulator 8 from Table 4(a)) on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD2). With reference to Figure 20, Neopentyl Glycol Diethylhexanoate has a difference (Δ) of 11 % after 30 mins, 21 % after 60 mins, and 53 % after 3 hours. Addition of the Neopentyl Glycol Diethylhexanoate in the test composition (MOD2) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Neopentyl Glycol Diethylhexanoate, drops in fragrance concentration over the 3 hours. Thus, Neopentyl Glycol Diethylhexanoate acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).

(c) Effect of Kolliphor ^® EL on Compositions having Volatile Fragrance Materials Figure 21 shows the effect of the substantially non-odorous fragrance modulator

Kolliphor ^® EL (disclosed as modulator 99 from Table 4(a)) on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD3). With reference to Figure 21, indole has a difference (Δ) of 15 % after 30 mins, 28 % after 60 mins, and 80 % after 3 hours. Addition of the Kolliphor ^® EL in the test composition (MOD3) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Kolliphor ^® EL, drops in fragrance concentration over the 3 hours. Thus, Kolliphor ^® EL acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown). Example 7 - Analytical Headspace Test Results

Using the analytical headspace Test Method 4, it is possible to demonstrate the character retention over time of a perfume mixture of a fragrance composition of the present invention vs. a control. Compositions disclosed in Tables 18(a)- 18(e) are added to sealed vials in accordance with the procotol described in the Method Section, and the fragrance profile in the headspace are measured at specific time points through the use of headspace gas chromatography.

(a) Effects of the Substantially Non- Odorous Fragrance Modulators on Character Retention of Compositions having Diamond Constructions vs. Compositions having Traditional Levels of Fragrance Materials

The test demonstrates the character retention over time of a fragrance composition. The results show the effect of the substantially non-odorous fragrance modulator and fragrance materials in a diamond construction for any one of the inventive Compositions Al, A2, A3, A4, A5, Dl, D2, D4, Gl, G2, G4, Jl, J2, J4, Ml, and M2 on fragrance profile versus control Compositions CI, C2, C3, C4, C5, Fl, F2, F4, II, 12, 14, LI, L2, L4, 01, and 02 in the absence of the substantially non-odorous fragrance modulator. Alternatively, results show the effect of the substantially non-odorous fragrance modulator and fragrance materials in a diamond construction for any one of the inventive Compositions Al, A2, A3, A4, A5, Dl, D2, D4, Gl, G2, G4, Jl, J2, J4, Ml, and M2 on fragrance profile longevity versus traditional Compositions Bl, B2, B3, B4, B5, El, E2, E4, HI, H2, H4, Kl, K2, K4, Nl, and N2 in the presence of the substantially non-odorous fragrance modulator. Fragrance profile fidelity, particularly of floral characters attributable to the volatile fragrance materials are maintained for up to at least 1 hour in the presence of the substantially non-odorous fragrance modulator whilst it drops in the absence of the substantially non-odorous fragrance modulator.

Figure 22(a)(i) provides the headspace chromatogram for control Composition L2 after

10 mins of evaporation, wherein Composition L2 comprises 7 wt% Traditional Muguesia Magnifica Fragrance Example 5a and no modulator. The headspace is a complex fragrance and many perfume materials can be observed spanning a range of volatility and characters. This includes: (1) moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C, for example: Cyclogalbanate or Majantol ^® , Helional, Cymal or Jasmal and hydroxycitronellal; and (2) low volatile fragrance materials having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C, for example: Hedione ^® HC and Iso-E Super ^® . As the fragrance evaporates, the height of the peaks reduces significantly, particularly the peaks due to the high and moderate volatile fragrance materials. After 60 mins of evaporation, as shown in Figure 22(a)(ii), only one substantial moderate volatile fragrance material peak remains, for example Helional. In contrast, the low volatile fragrance materials remain with substantial peaks for many perfume materials, for example Hedione ^® HC and Iso-E Super ^® . These chromatograms illustrate the loss of fragrance materials during evaporation, particularly the loss of the moderate volatile fragrance materials. Olfactively this is perceived as a loss in intensity and perception of these particular fragrance materials, particularly those that provide the floral characters.

Figure 22(b)(i) provides the headspace chromatogram for inventive Composition J2 after 10 mins of evaporation, wherein Composition J2 comprises 7 wt% Diamond Muguesia Magnifica Fragrance Example 5b and 15 wt% PPG- 11 Stearyl Ether substantially non-odorous fragrance modulator. The headspace is a complex fragrance and many perfume materials can be observed spanning a range of volatility and characters. This includes: (1) moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C, for example: Cyclogalbanate or Majantol ^® , Helional, Cymal or Jasmal and hydroxy citronellal; and (2) low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C, for example Hedione ^® HC and Iso-E Super ^® . As the fragrance evaporates the height of the peaks reduces but not as much as compared to the control Composition L2, particularly the peaks due to the moderately volatile fragrance materials are maintained. After 60 mins of evaporation, as shown in Figure 22(b)(ii), most of the moderate volatile fragrance materials peaks remain. This includes Cyclogalbanate or Majantol ^® , Helional, Cymal or Jasmal and hydroxy citronellal. The low volatile fragrance materials, Hedione ^® HC and Iso-E Super ^® , remain in the headspace but are not dominant when compared to Composition L2. These chromatograms illustrate the prolonged presence of the volatile fragrance materials in Composition J2 and the dominance of the headspace after 60 mins by the moderate volatile fragrance materials at the expense of the low volatile fragrance materials. Consumers will experience this as a fragrance with a prolonged intensity, particularly of the characters attributable to the volatile fragrance materials, most particularly of the floral characters.

Figure 23(a)(i) provides the headspace chromatogram for control Composition C4 after 10 mins of evaporation, wherein Composition C4 comprises the Traditional Muguesia Magnifica Fragrance Example 5 a and no modulator. The headspace is a complex fragrance and many perfume materials can be observed spanning a range of volatility and characters. This includes: (1) moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C, for example: Cyclogalbanate or Majantol ^® , Phenethyl alcohol, Cymal or Jasmal, and hydroxy citronellal and (2) low volatile fragrance materials having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C, for example: Hedione ^® HC and Iso-E Super ^® . As the fragrance evaporates, the height of the peaks reduces significantly, particularly the peaks due to the moderate volatile fragrance materials. After 60 mins of evaporation, as shown in Figure 23(a)(ii), only two small moderate volatile fragrance material peaks remain, Helional and Cyclogalbante or Majantol. In contrast, the low volatile fragrance materials remain with many peaks for many perfume materials, for example Hedione ^® HC and Iso-E Super ^® . These chromatograms illustrate the loss of fragrance materials during evaporation, particularly the loss of the moderate volatile fragrance materials. Olfactively this is perceived as a loss in intensity and perception of these particular fragrance materials, particularly those that provide the floral characters.

Figure 23(b)(i) provides the headspace chromatogram for inventive Composition A4 after 10 mins of evaporation, wherein Composition A4 comprises the Diamond Muguesia Magnifica Fragrance Example 5b and PPG-20 Methyl Glucose Ether (i.e., GLUCAM™ P-20) substantially non-odorous fragrance modulator. The headspace is a complex fragrance and many perfume materials can be observed spanning a range of volatility and characters. This includes: (1) moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C, for example: Cyclogalbanate or Majantol ^® , Phenethyl alcohol, Cymal or Jasmal, and hydroxycitronellal; and (2) low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C, for example Hedione ^® HC and Iso-E Super ^® . As the fragrance evaporates the height of the peaks reduces but not as much as compared to the control Composition C4, particularly the peaks due to the moderate volatile fragrance materials are maintained. After 60 mins of evaporation, as shown in Figure 23(b)(ii), most of the moderate volatile fragrance materials peaks remain. This includes Cyclogalbanate or Majantol ^® , Phenethyl alcohol, Cymal or Jasmal, and hydroxycitronellal. The low volatile fragrance materials, Hedione ^® HC and Iso-E Super ^® , remain in the headspace but are not dominant when compared to Composition C4. These chromatograms illustrate the prolonged presence of the volatile fragrance materials in Composition A4 and the dominance of the headspace after 60 mins by the moderate volatile fragrance materials at the expense of the low volatile fragrance materials. Olfactively this is perceived as a fragrance with a prolonged intensity, particularly of the characters attributable to the moderate volatile fragrance materials, most particularly of the floral characters.

Figure 24(a)(i) provides the headspace chromatogram for control Composition L4 after 10 mins of evaporation, wherein Composition L4 comprises the Traditional Floral Magnifica Fragrance Example 4a and no modulator. The headspace is a complex fragrance and many perfume materials can be observed spanning a range of volatility and characters. This includes: (1) moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C, for example: Pyranol (Florol), Cyclogalbanate or Majantol ^® , Cymal or Jasmal, and hydroxycitronellal and (2) low volatile fragrance materials having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C, for example: Hedione ^® HC and Iso-E Super ^® . As the fragrance evaporates, the height of the peaks reduces significantly, particularly the peaks due to the moderate volatile fragrance materials. After 60 mins of evaporation, as shown in Figure 24(a)(ii), only a few small moderate volatile fragrance material peaks remain, Cymal or Jasmal and Helional. In contrast, the low volatile fragrance materials remain with many peaks for many perfume materials, for example Hedione ^® HC and Iso-E Super ^® . These chromatograms illustrate the loss of fragrance materials during evaporation, particularly the loss of the moderate volatile fragrance materials. Olfactively this is perceived as a loss in intensity and perception of these particular fragrance materials, particularly those that provide the floral characters.

Figure 24(b)(i) provides the headspace chromatogram for inventive Composition J4 after

10 mins of evaporation, wherein Composition J4 comprises the Diamond Floral Magnifica Fragrance Example 4b and Isocetyl Alcohol (i.e., Ceraphyl ^® ICA) substantially non-odorous fragrance modulator. The headspace is a complex fragrance and many perfume materials can be observed spanning a range of volatility and characters. This includes: (1) moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C, for example: Pyranol (Florol), Cyclogalbanate or Majantol ^® , Cymal or Jasmal, and hydroxy citronellal; and (2) low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C, for example Hedione ^® HC and Iso-E Super ^® . As the fragrance evaporates the height of the peaks reduces but not as much as compared to the control Composition C4, particularly the peaks due to the moderate volatile fragrance materials are maintained. After 60 mins of evaporation, as shown in Figure 24(b)(ii), most of the moderate volatile fragrance materials peaks remain. This includes Pyranol (Florlol), Cyclogalbanate or Majantol ^® , Cymal or Jasmal, and hydroxy citronellal. The low volatile fragrance materials, Hedione ^® HC and Iso-E Super ^® , remain in the headspace but are not dominant when compared to Composition C4. These chromatograms illustrate the prolonged presence of the volatile fragrance materials in Composition A4 and the dominance of the headspace after 60 mins by the moderate volatile fragrance materials at the expense of the low volatile fragrance materials. Olfactively this is perceived as a fragrance with a prolonged intensity, particularly of the characters attributable to the moderate volatile fragrance materials, most particularly of the floral characters.

Figure 25(a)(i) provides the headspace chromatogram for control Composition 14 after 10 mins of evaporation, wherein Composition 14 comprises the Traditional Muguesia Magnifica Fragrance Example 5 a and no modulator. The headspace is a complex fragrance and many perfume materials can be observed spanning a range of volatility and characters. This includes: (1) moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C, for example: Cyclogalbanate or Majantol ^® , Helional, Cymal or Jasmal, and hydroxy citronellal and (2) low volatile fragrance materials having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C, for example: Hedione ^® HC and Iso-E Super ^® . As the fragrance evaporates, the height of the peaks reduces significantly, particularly the peaks due to the high and moderate volatile fragrance materials. After 60 mins of evaporation, as shown in Figure 25(a)(ii), only one substantial moderate volatile fragrance material peak remains, Helional. In contrast, the low volatile fragrance materials remain with substantial peaks for many perfume materials, for example Hedione ^® HC and Iso-E Super ^® . These chromatograms illustrate the loss of fragrance materials during evaporation, particularly the loss of the moderate volatile fragrance materials. Olfactively this is perceived as a loss in intensity and perception of these particular fragrance materials, particularly those that provide the floral characters.

Figure 25(b)(i) provides the headspace chromatogram for inventive Composition G4 after 10 mins of evaporation, wherein Composition G4 comprises the Diamond Muguesia Magnifica Fragrance Example 5b and Undecyl Glucoside (i.e., Simulsol ^® SL 11W) substantially non- odorous fragrance modulator. The headspace is a complex fragrance and many perfume materials can be observed spanning a range of volatility and characters. This includes: (1) moderate volatile fragrance materials having a vapor pressure in the range of 0.1 Torr to 0.001 Torr (0.0133 kPa to 0.000133 kPa) at 25 °C, for example: Cyclogalbanate or Majantol ^® , Helional, Cymal or Jasmal and hydroxy citronellal; and (2) low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25 °C, for example Hedione ^® HC and Iso-E Super ^® . As the fragrance evaporates the height of the peaks reduces but not as much as compared to the control Composition 14, particularly the peaks due to the moderately volatile fragrance materials are maintained. After 60 mins of evaporation, as shown in Figure 25(b)(ii), most of the moderate volatile fragrance materials peaks remain. This includes Cyclogalbanate or Majantol ^® , Helional, Cymal or Jasmal and hydroxycitronellal. The low volatile fragrance materials, Hedione ^® HC and Iso-E Super ^® , remain in the headspace but are not dominant when compared to Composition 14. These chromatograms illustrate the prolonged presence of the volatile fragrance materials in Composition G4 and the dominance of the headspace after 60 mins by the moderate volatile fragrance materials at the expense of the low volatile fragrance materials. Olfactively this is perceived as a fragrance with a prolonged intensity, particularly of the characters attributable to the moderate volatile fragrance materials, most particularly of the floral characters.

It should be understood that every maximum numerical limitation given throughout this specification includes every lower numerical limitation, as if such lower numerical limitations were expressly written herein. Every minimum numerical limitation given throughout this specification will include every higher numerical limitation, as if such higher numerical limitations were expressly written herein. Every numerical range given throughout this specification will include every narrower numerical range that falls within such broader numerical range, as if such narrower numerical.

The dimensions and values disclosed herein are not to be understood as being strictly limited to the exact numerical values recited. Instead, unless otherwise specified, each such dimension is intended to mean both the recited value and a functionally equivalent range surrounding that value. For example, a dimension disclosed as "40 mm" is intended to mean "about 40 mm."

Every document cited herein, including any cross referenced or related patent or application and any patent application or patent to which this application claims priority or benefit thereof, is hereby incorporated herein by reference in its entirety unless expressly excluded or otherwise limited. The citation of any document is not an admission that it is prior art with respect to any invention disclosed or claimed herein or that it alone, or in any combination with any other reference or references, teaches, suggests or discloses any such invention. Further, to the extent that any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall govern.

While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.