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Title:
FULLERENE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2005/061444
Kind Code:
A1
Abstract:
It is intended to provide a fullerene derivative comprising a site to which a sugar chain can be specifically attached regardless of the sugar chain type and a fullerene nucleus. It is also intended to provide a novel sugar chain analysis technique with the use of the principle of largely shifting a sugar chain signal alone from a molecular weight region involving a large number of various biological molecules in mass spectroscopy. It is furthermore intended to provide a method of constructing a sugar chain-capturing support with the use of the membrane characteristics of a sugar chain-capturing fullerene derivative to thereby separate, purify, concentrate or analyze a sugar chain or a sugar chain-containing substance at a high efficiency and/or in a state closely similar to the naturally occurring state, and a system and an apparatus to be used therefor. Namely, a novel fullerene derivative comprising a site capable of interacting specifically with a sugar chain and a fullerene nucleus; and a method of separating, concentrating or purifying a sugar chain or a sugar chain-containing substance in a sample with the use of a sugar chain-capturing support containing the fullerene derivative.

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Inventors:
NISHIMURA SHINICHIRO (JP)
ABE SHIGEAKI (JP)
MORIYAMA HIDEKI (JP)
Application Number:
PCT/JP2004/017814
Publication Date:
July 07, 2005
Filing Date:
November 30, 2004
Export Citation:
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Assignee:
SHIONOGI & CO (JP)
NISHIMURA SHINICHIRO (JP)
ABE SHIGEAKI (JP)
MORIYAMA HIDEKI (JP)
International Classes:
C07C239/20; (IPC1-7): C07C239/20
Foreign References:
JPH08509232A1996-10-01
JPH10506106A1998-06-16
JP2002212197A2002-07-31
Attorney, Agent or Firm:
Yamamoto, Shusaku (Crystal Tower 2-27 Shiromi 1-chome, Chuo-k, Osaka-shi Osaka 15, JP)
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