Title:
FULLY-AUTOMATIC GENE-READING INTEGRATED CHIP
Document Type and Number:
WIPO Patent Application WO/2019/022299
Kind Code:
A9
Abstract:
The present invention relates to a full-automatic gene-reading integrated chip and, more particularly, to a full-automatic gene-reading integrated chip adapted to rapidly read a gene of bacteria to be detected, in a fully automated manner. The configuration of the present invention provides a fully-automatic gene-reading integrated chip comprising: a concentration extractor for enriching a bacteria to be detected by discharging a foreign matter solution out of a combined solution in which a detaching solution and magnetic particles are combined and for extracting a gene from the enriched bacteria to be detected; a mixer, arranged downstream of the concentration extractor, for mixing the gene and a PCR buffer to form a mixed PCR solution; an amplifier, arranged downstream of the mixer, for performing a polymerase chain reaction (PCR) with the mixed PCR solution to give an amplified solution; a quantitative injector, arranged between the mixer and the amplifier, for injecting a determined quantity of the mixed PCR solution to the amplifier; a combiner, arranged downstream of the amplifier, for combining a signaling substance with the amplification solution amplified by the amplifier to form a combined matter; and a reader, arranged downstream of the combiner, for reading the gene contained in the combined matter, wherein the reader measures a current amount of the combined matter to read the gene.
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Inventors:
LEE TAE JAE (KR)
SHIN SU JEONG (KR)
LIM SUN YOUNG (KR)
KIM CHI HYUN (KR)
SHIN SEOL YI (KR)
LEE MOON KEUN (KR)
LEE KYOUNG GYUN (KR)
BAE NAM HO (KR)
LEE SEOK JAE (KR)
SHIN SU JEONG (KR)
LIM SUN YOUNG (KR)
KIM CHI HYUN (KR)
SHIN SEOL YI (KR)
LEE MOON KEUN (KR)
LEE KYOUNG GYUN (KR)
BAE NAM HO (KR)
LEE SEOK JAE (KR)
Application Number:
PCT/KR2017/011246
Publication Date:
May 16, 2019
Filing Date:
October 12, 2017
Export Citation:
Assignee:
KOREA ADVANCED INST SCI & TECH (KR)
International Classes:
B01L3/00; B01L7/00; G01N35/08
Attorney, Agent or Firm:
HAN, Sang Soo (KR)
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