FULVESTRANT DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF

Title:

FULVESTRANT DERIVATIVE, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/103929

Kind Code:

A1

Abstract:

Provided are a fulvestrant derivative, and a preparation method therefor and the medical use thereof. Specifically, provided are a fulvestrant derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing same, and the use thereof in treating breast cancer.

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Inventors:

WU MAOJIANG (CN)
XU MIAOHUAN (CN)
YANG BAOJIE (CN)

Application Number:

PCT/CN2022/136446

Publication Date:

June 15, 2023

Filing Date:

December 05, 2022

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Assignee:

JIANGSU YAHONG MEDITECH CO LTD (CN)
ASIERIS PHARMACEUTICALS SHANGHAI CO LTD (CN)

International Classes:

C07J31/00; A61K31/567; A61P35/00; C07J41/00

Domestic Patent References:

WO2019046491A1	2019-03-07
WO2021100029A2	2021-05-27
WO2019224790A2	2019-11-28

Foreign References:

CN106715456A	2017-05-24
CN108137482A	2018-06-08

Attorney, Agent or Firm:

GE CHENG & CO., LTD. (CN)

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