Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
FUNCTION-BASED PROBES FOR ENVIRONMENTAL MICROBIOME ANALYSIS AND METHODS OF MAKING AND USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2019/053700
Kind Code:
A3
Abstract:
Probe embodiments for identifying analytes involved in biofuel or bioenergy production, bioremediation, or nutrient cycling as well as methods of making and use are described herein. In some embodiments, probes identifying cellulose degradation and/or sugar transport, lignin or chitin degradation, or peptide or toxin metabolism are included. In some embodiments, probes for identifying analytes in a soil sample are included in the compositions and methods disclosed herein.

Inventors:
WRIGHT, Aaron T. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
RAMOS-HUNTER, Susan (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
SADLER, Natalie C. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
Application Number:
IB2018/058935
Publication Date:
August 08, 2019
Filing Date:
November 13, 2018
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
BATTELLE MEMORIAL INSTITUTE (902 Battelle Boulevard, Richland, Washington, 99354, US)
WRIGHT, Aaron T. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
RAMOS-HUNTER, Susan (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
SADLER, Natalie C. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
FREDRICKSON, JIM K. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
ROMINE, MARGARET F. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
WHIDBEY, CHRISTOPHER-MYCHAEL (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
STODDARD, ETHAN G. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
KILLINGER, BRYAN J. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
NAIR, REJI N. (P.O. Box 999 M/S K1-5, Richland Washington, 99352, US)
International Classes:
G01N33/548; C07C305/24; C07D229/02; C07F9/09; C07H9/00; C07H13/12; C07H15/22; C07H15/26; G01N33/569
Foreign References:
US20110020837A12011-01-27
Other References:
LIU, X. ET AL.: "Exploring the Binding Proteins of Glycolipids with Bifunctional Chemical Probes", ANGEW. CHEM. INT. ED., vol. 55, no. 46, 2016, pages 14330 - 14334, XP055628145
WRIGHT, A. T. ET AL.: "A Suite of Activity-Based Probes for Human Cytochrome P450 Enzymes", J. AM. CHEM. SOC., vol. 131, no. 30, 2009, pages 10692 - 10700, XP055537695, doi:10.1021/ja9037609
HONG, S. ET AL.: "Live- Cell Stimulated Raman Scattering Imaging of Alkyne-Tagged Biomolecules", ANGEW. CHEM. INT. ED., vol. 53, no. 23, 2014, pages 5827 - 5831, XP055628167
CHAUVIGNE-HINES, L. M ET AL.: "Suite of Activity-Based Probes for Cellulose-Degrading Enzymes", J. AM. CHEM. SOC., vol. 134, no. 50, 2012, pages 20521 - 20532, XP055537686, doi:10.1021/ja309790w
Attorney, Agent or Firm:
SCHWARTZ, Johanna P. (Klarquist Sparkman, LLPOne World Trade Center, Suite 1600,121 SW Salmon Stree, Portland Oregon, 97204, US)
Download PDF: