AND COMPOSITION'

Field of the invention:

5

The present invention relates to use of the herbal formulation comprising the synergistic combination of fiber/powder/granules of the aerial parts of at least two plants selected from ; .. . the group comprising of Hemedesmus indicus, Acorus calamus, Murraya Koenigii, Alpinia galanga, Papaver somniferum, Amorphophallus campanulatus, Hygrophila auriculata, 0 Hygrophila schulli, Cuminum cyminum, Apium graveolens, Colocasia esculenta along with one or more flavoring agents selected from essential/aromatic oils.

More particularly, it relates to the use of the said formulation in formulated products such as bidis and cigarettes/ snuffs/ chewing gums.

5 Background and prior art of the invention:

For the joy of living, medicated smoke should become a part of the daily routine. When used as therapy, the smoke is inhaled through the nose for head and neck disease, and through the mouth for throat disorders. The potential advantages of delivering a drug to 0 the lung by inhalation have been well known to physicians and drug abusers for years. For drugs that exert their biological effect in the lung, these include rapid onset of action, reduced dose and minimized side effects compared to the same drug delivered by mouth. First line asthma therapy is currently based on inhaled corticosteroids which minimize the problems associated with oral steroids, such as adrenal suppression, electrolyte imbalance 5 and muscle weakness. Tobacco smoke has been used in western culture for more than 400 years; human inhalation of cigarette smoke is a twentieth century phenomenon with major medical and economic consequences. However, excessive smoking is now recognized as one of the major health problems throughout the world. The most important difficulty results from the fact that heavy smokers are dependent on nicotine, which is considered to 0 be one of the risk factors in tobacco smoke. During the combustion of tobacco the important risk factors formed such as carbon monoxide, tar products, aldehydes and hydrocyanic acid (US patent 5335678). US patent 20040103908 describes the herbal

cigarette free from the existing tobacco cigarettes contains a predetermined mixture of different herbs packed in the filtered or non-filtered cigarette paper tubes. The US patent 6497234 relates to a mixture of herbs and other natural products that can be used as a healthy substitute for tobacco and also alleviates the addictive effects of nicotine, and provides an aid to quit smoking tobacco-related products. Whereas, the US patent 20050061828 invention relates generally to the field of packaging machines which provides for the packaging of at least two types of smoking products consisting of tobacco cigarettes/cigars and bidis. None of the prior art discloses functional cigarettes controlling body weight. Accordingly studies were undertaken to develop a herbal cigarette controlling body weight and composition that benefits in innumerable ways the health of our body and mind

Objects of the invention:

The main object of the present invention is to provide the use of the herbal formulation comprising the synergistic combination of fiber/powder/granules of the aerial parts of at least two plants selected from the group comprising of Hemedesmus indicus, Acorus calamus, Murraya Koenigii, Alpinia galanga, Papaver somniferum, Amorphophallus campanulatus, Hygrophila auriculata, Hygrophila schulli, Cuminum cyrninum, Apium graveolens, Colocasia esculenta along with one or more flavoring agents selected from essential/aromatic oils.

Another object of the present invention is to provide the use of the said herbal formulation in formulated products such as bidis and cigarettes/ snuffs/ chewing gums.

Further object of the present invention is to provide novel herbal cigarette in controlling body weight and change in body weight composition.

Summary of the invention:

The invention deals with the use of the herbal formulation comprising the synergistic combination of fiber/powder/granules of the aerial parts of at least two plants selected from

the group comprising of Hemedesmus indicus, Acorus calamus, Murraya Koenigii, Alpinia galanga, Papaver somniferutn, Amorphophallus campanulatus, Hygrophila auriculata, Hygrophila schulli, Cuminum cyminum, Apium graveolens, Colocasia esculenta along with one or more flavoring agents selected from essential/aromatic oils and in the development of aphrodisiac develop a novel herbal cigarette in controlling body weight and change in body weight composition. The novelty of the present investigation lies in providing (1) control of over weight; (2) which helps in the cure or relief from asthma or respiratory diseases and improves the digestion and evacuation of bowel; (3) spreads good aroma to the surrounding and ties up the good relations in business and profession and relief stress; (4) removes the higher bad fat content.

Detailed description of the present invention:

Accordingly, the present invention provides use of the herbal formulation comprising the synergistic combination of fiber/powder/granules of the aerial parts of at least two plants selected from the group comprising of Hemedesmus indicus, Acorus calamus, Murraya

Koenigii, Alpinia galanga, Papaver somniferum, Amorphophallus campanulatus,

Hygrophila auriculata, Hygrophila schulli, Cuminum cyminum, Apium graveolens,

Colocasia esculenta along with one or more flavoring agents selected from essential/aromatic oils.

In an embodiment of the present invention, the said formulation further comprising upto 50% of the said formulation and the rest being the conventional additives along with tobacco.

In another embodiment of the present invention, the synergistic combination of fiber/powder/granules are mixed in the ratio of Hemedesmus indicus (2-8%), Acorus calamus (0.05-1.2%), Murraya Koenigii (1-8%), Alpinia galangal (2-15%), Papaver somniferum (0.5-13.5%), Amorphophallus campanulatus (2.5-7.5%), Hygrophila auriculata (1-15%), Hygrophila schulli (0.5%-7.8%) Cuminum cyminum(2-3%), Apium graveolensβ- 5%), Colocasia esculenta(2-5%) along with one or more specific flavoring agents selected from essential/aromatic oils.

Further, in an embodiment of the present invention, the essential/aromatic oils are selected from the group comprising of clove, eucalyptus, Angelica archangel, Apium graveolens, Cananga odorata, Carum carvi, Citrus aurantifolia, Citrus limonum, Cymbopogon citrates, Cymbopogon martinii, Cinnamomum verum, Lavandula angustifolia, Lavendula officinalis, Melaleuca alternifolia, Myristica fragrans, Pelargonium graveolens, Rosa damascene, Santalum album, Jasminum multiflorum, Jasminum sambac, Ocimum sanctum, Ocimum gratissimum, Allium cepa, Allium sativum and Nicotiana tabacum.

Yet in an embodiment of the present invention, the use of the herbal formulation in formulated products such as bidis and cigarettes/ snuffs/ chewing gums.

Still in an embodiment of the present invention, the said formulated product is effective in reduction of over weight.

Still in an embodiment of the present invention, the said formulated product helps in removing depression.

Still in an embodiment of the present invention, the said formulated product helps in relieving stress.

Still in an embodiment of the present invention, the said formulated product spreads fragrance or good aroma in surrounding.

Still in an embodiment of the present invention, the said formulated product helps in curing or relieving asthma or breathing difficulties.

Still in an embodiment of the present invention, the said formulated product helps in improving the digestion and evacuation of bowel.

Still in an embodiment of the present invention, the said formulated product scavenges the free radicals and acts as potent antioxidant.

Still in an embodiment of the present invention, the said formulated product is non-irritating to eye, nose and does not possess itching property.

Still in an embodiment of the present invention, the said formulated product is non-irritating and having no toxic- effects, no itching, no breathing problems, no bronchial irritation, and no pain in nose, ear and throat.

Still in an embodiment of the present invention, the said formulated product helps in improving the potent enzymatic superoxide dismutase enhancing activity.

Still in an embodiment of the present invention, the said formulated product helps in defending the body against the effect of stressful environment and provides vitality and energy.

The present invention also provides a herbal formulation comprising the synergistic combination of fiber/powder/granules of the aerial parts of at least two plants selected from the group comprising of Hemedesmus indicus, Acorus calamus, Murraya Koenigii, Alpinia galanga, Papaver somniferum, Amorphophallus campanulatus, Hygrophila auriculata, Hygrophila schulli, Cuminum cyminum, Apium graveolens, Colocasia esculenta along with one or more flavoring agents selected from essential/aromatic oils.

In an embodiment of the present invention, the said formulation further comprises upto 50% of the said formulation and the rest being the conventional additives along with tobacco. In another embodiment of the present invention, the synergistic combination of fiber/powder/granules are mixed in the ratio of Hemedesmus indicus (2-8%), Acorus calamus (0.05-1.2%), Murraya Koenigii (1-8%), Alpinia galangal (2-15%), Papaver somniferum (0.5-13.5%), Amorphophallus campanulatus (2.5-7.5%), Hygrophila auriculata (1-15%), Hygrophila schulli (0.5%-7.8%) Cuminum cyminum(2-3%), Apium graveolensβ- 5%), Colocasia esculenta(2-5%) along with one or more specific flavoring agents selected from essential/aromatic oils.

Further, in an embodiment of the present invention, the essential/aromatic oils are selected from the group comprising of clove, eucalyptus, Angelica archangel, Apium graveolens, Cananga odorata, Carum carvi, Citrus aurantifolia, Citrus limonum, Cymbopogon citrates,

Cymbopogon martinii, Cinnamomum verum, Lavandula angustifolia, Lavendula officinalis, Melaleuca altemifolia, Myristica fi-agrans, Pelargonium graveolens, Rosa damascene, Santalum album, Jasminum multiflorum, Jasminum sambac, Ocimum sanctum, Ocimum gi'atissimum, Allium cepa, Allium sativum and Nicotiana tabacum.

Further, the present invention also provides herbal bidis / cigarettes / snuffs / chewing gums comprising the herbal formulation.

In an embodiment of the present invention, the said Herbal bidis / cigarettes / snuffs / chewing gums contain low tar content.

The plants used in the preparation of the functional cigarettes with slimming property have been reported to have following descriptive characters Hemidesmus indicus Family: Asclepiadaceae

Botanical Description- A slender, twining or prostate perennial shrub with cylindrical stems, thickened at the nodes, and aromatic roots. Leaves simple, opposite or whorled, short-petioled, variable in shape from broadly ovate to oblong-elliptic , linear or linear- lanceolate, obtuse or apiculate,3-10 cm long and 0.3-3.8 cm wide, base acute, rounded or truncate, apex rounded or emarginate and apiculate, leathery , dark green above, often variegated with white along the veins, paler beneath , leaves on flowering shoots broader and brighter green than other leaves; petioles 0.1-0.6 cm long. Flowers small, greenish yellow outside and purplish inside, crowded in subsessile axillary cymes shorter than the leaves; calyx deeply 5-lobed, glandular within; corolla 5- partite, 0.6-0.8 cm in diameter when expanded, lobes thick, ovate-oblong. Fruit (follicle) glabrous,often purplish, slender, cylindrical , sometimes curved, 10-12 cm long and 0.5-0.6 cm wide, divaricate, containing numerous black, flattened ,ovate-oblong seeds with a silvery -white coma. Flowers mainly between july and October and fruits from October to February within its Indian range.

Distribution and habitat- Common in open deciduous and scrub forests, hedges and on degraded sites from the upper gangetic plains of northern India eastwards to Assam and southwards through peninsular India to srilanka.

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Medicinal properties and uses- The dried roots, known commercially as Hemidusmus or Anantamul, are official in the Indian pharmacopoeia. The root and root bark are considered tonic, alternative, demulcent, diaphoretic, diuretic and blood purifying. They are used in several well known ayurvedic preparations for treating bowel complaints, elephantiasis, fever, nausea, and vomiting. Administered in powder form or as an infusion, decoction or syrup, it is prescribed for fever, leucorrhoea, chronic rheumatism and skin diseases. The root paste is applied to the forehead to reduce fever among the paharia in southern Bihar. Among the kondhs of south western Orissa, the crushed root is applied externally to relieve itching and its decoction is used to control excessive menstrual flow, or mixed with mother's milk to check diarhoea in infants. A hot infusion of the root bark with milk and sugar is given to children to relieve chroniccough and diarrhea. In kerela, the milky latex is used to relieve eye inflammation. Acorus calamus . Family: Araceae

Botanical Description- A strongly aromatic semi-aquatic perennial herb; rhizomes creeping, jointed, somewhat vertical compressed, 1.3-2.5 cm thick, pale to dark brown and spongy inside. Leaves narrow up to 80cm long ,linear to narrowly ensi form , glossy bright green , apex acute, base amplexicaul; petioles sheathing for 20-50cm. flowers pale green, fragrant ,arranged compactly on a sessile, cylindrical, stumpy spadix 5-7cm long. Fruits (berries) green, angular, 3-celled, fleshy, containing 1-3 oblong seeds.

Distribution and Habitat- Native to Europe, cultivated and sometimes naturalized throughout India, Myanmar (Burma) and Srilanka. Common in moist or marshy habitats between 300 and 2000 m elevation in the Himalayas.

Medicinal properties and uses- The dried rhizomes comprise the commercial drug calamus, used in Europe since the time of Hippocrates. In ayurveda they constitute the drug Vaca, considered to have antispasmodic, carminative and anthelmintic properties and to be capable of improving memory and intellect. It is used in various forms (as a powder, balm, enema or pills) to treat a wide variety of diseases and conditions, including epilepsy and other mental ailments, chronic diarrhea and dysentery, bronchial caratacts, intermittent

fevers and glandular and abdominal tumors, liver and kidney ailments, rheumatism and eczema. The rhizomes are an ingredient in many compound ayurvedic and other traditional medicinal preparations. The rhizomes, roots and leaves yield a light brown to brownish- yellow volatile oil known as calamus oil. , credited with carminative, antispasmodic and antibacterial properties. Among the gonds of Uttarpradesh the roots bark, taken together with black pepper, is reportedly used as an antidote for snakebite. Murraya Koenigii Family: Rutaceae

Botanical Description- A large shrub or small evergreen or deciduous tree to 5m tall with a short trunk, thin, smooth, grey or brown bark and a dense , shady crown. Most parts of the plant are covered with fine down and have a strong, peculiar smell. Leaves pinnately compound, 15-3 Ocm long, arranged spirally, crowded on the ends of branchlets, rachis terete, pubescent, petioles 1.2-1.5 cm long; leaflets 11-25, alternate on rachis, 2.5-3.5 cm long, ovate-lanceolate with an oblique base, margins irregularly crenate, pubescent beneath, petioles 2-3 mm long. Flowers white, 0.8-1 cm long, numerous in broad terminal clusters, calyx pubescent, lobes triangular, subacute; petal 6mm long, linear-oblong, rounded at apex, gland-dotted. Fruits ovoid to subglobose, wrinkled or rough with glands, to 2.5cm long and 0.8 cm in diameter, purplish-black when ripe; 2-seeded. Flowers mainly between February and April, and fruits between April and August, depending on locality.

Distribution and habitat - Native to tropical Asia from the Himalayan foothills of India to Srilanka eastwards through Myanmar, Indochina, Southern china and Hainan. Frequently cultivated throughout India and elsewhere in the tropics of its leaves, used to flavor curries; sometimes naturalized outside its native range.

Medicinal properties and uses- The plant is highly valued for its leaves, an important ingredient in Indian cuisine, to promote appetite and digestion. In Ayurveda, they enter into several important compound preparations, and are considered useful for destroying pathogenic organisms and poisons, and treating skin diseases, worm, infestation and neurosis. The raw green leaves or their decoction are taken orally to treat dysentery and as a febrifuge. Crushed leaves are applied externally to cure skin eruptions and to relieve

burns. The bark and roots are used as stimulants, and are applied externally to cure skin eruptions and to treat the bites of poisonous animals.

Hygrophila auricuϊata Family: Acanthaceae

Botanical Description- A stout herb up to 1.5m high, more or less hispid with long hairs; stems numerous, erect, usually unbranched ,subquadangular , thickened at the nodes. Leaves in whorls of 6, the outer 2 the largest, oblong-lancoelate or oblanceolate, upto 18cm long and 3.2cm wide, with sharp , yellow, axillary spines; the two outer leaves of each whorl larger and others much smaller. Flowers bluish- purple, in sessile axillary whorls; calyx 4-partite, lobes unequal, clothed with soft hairs; corolla distinctly 2-lipped, the upper2-lobed , the lower 3-lobed. Fruits 0.8cm long, linear -oblong, pointed , containing 4-8 orbicular seeds. Flowers between October and December in central Indian deciduous forest regions.

Distribution and habitat - Throughout the plains of India, in moist habitats such as marshy margins of canals and rice fields. Also found in tropical Himalayas, Myanmar, Indonesia and Malaysia.

Medicinal properties and uses- hi ayurveda, seeds and roots comprise the drug Kolilaksah, a reputed remedy for arthritis. The bitter seeds are considered aphrodiasiac and tonic and are used as a uterine sedative for pregnant women, and for treating diseases of biliousness. The seeds are given with sugar or milk in the treatment of impotence,gonorrhoea and spermatorrhoea. A paste of the seeds mixed with buttermilk or whey, is given for diarrhoea. A decoction of the roots is used as a diuretic and to treat rheumatism , gonorrhoea, and other diseases of the genito-urinary tract, jaundice and anasarca. The leaves are considered oleaginous , tonic , aphrodisiac and hypnotic; they are used to treat diarrhea, dysentery, thirst, urinary calculi and urinary discharges, inflammations, constipation, abdominal troubles. Among the rural inhabitant of Bhavnagar district of Gujarat, the whole plant is reportedly used to treat jaundice ,dropsy, and rheumatism. In unani system , the plant is known as Talamakhana, the leaves being considered useful for relieving cough; they are applied externally to treat gleet, lumbago

and joint pains. In siddha,the flower, seeds and whole plant are used for treating anaemia, dropsy, ascites, constipation, piles and aphrodisiac.

Alpinia galanga Family: Zingeberaceae

Botanical DescriptionrDried rhizomes constitute greater galangal. Used in rheumatism and bronchial catarrh; also considered stimulant and carminative. Rhizome yields an essential oil, used in perfumery as a source of methyl cinnamate and cineol. They are used for pickling; as condiment, and for seasioning fish; also substituted for ginger.

Medicinal properties and uses: Flowers eaten raw or pickled. Herb accredited with antitubercular properties. Seeds used for colic,diarrhea and vomiting , and as a sternutatory.

Papaver somniferum Family: Papaveraceae

Part used: Leaves

Botanical Description: Cultivated for production of opium which is harvested by incising the capsules at a particular stage known as "industrial maturity"; the product of first lancing contains higher percentage of morphine. Opium used as a narcotic,sedative, anodyne, antispasmodic, hypnotic ,and sudorific. Whole opium is much less used, its pure alkaloids, moiphine and codeine and their salts are preferred.

Medicinal properties and uses: Eating of opium creates a sense of euphoria and is habit forming; consumed orally, by smoking, and by injection. Poppy seed oil used for culinary pouposes, free from narcotic action; also used in dairrhoea and dysentery and in compositions for skin care. Capsules contain the same constituens as opium; infusion applied as a soothing application. Extract used as a sedative against irritating cough. Amorphophallus campanulatus Family: Araceae

Botanical description: A tuberous, stout, indigenous herb, 1.0-1.5m found almost throughout India. Tubers depressed, globose or hemispherical, dark brown out side, pale dull brown, sometimes almost white, with numerous long roots; leaves solitary, tripartite, 30-90 cm broad.

Medicinal uses: The corms are irritant due to the presence of calcium oxalate. It can also be made pickles. The stems can be used as cattle feed. They are rich in nutrients and minerals. They are carminative, aperient and expectorant. The fresh ones are an acrid stimulant and expectorant and increase appetite and taste. They are applied to treat acute rheumatism. They are also used in dysentery, piles and haemorrhoids.

Phytochemistry: It is nutritious and food values compares well with other stablished. It contains proteins, fat, fiber, carbohydrates, starch, oxalic acid and minerals calcium, phosphorus, Iron and vitamin A. Besides these, glucose, galactose and xylose are also present. The presence of an active diastatic enzyme is reported. The corm contains betulinic acid, beta sitosterol, stigmasterol and beta sitosterol palmitate.

Pharmacology: The methanolic extract of the corms showed significant effect on the uterus of the guinea pig. The fermented juice of the petioles is used to cure diarrhea. The seeds are also applied externally as irritant in treating rheumatic swelling. Hygrophila auriculata Family: Acanthaceae

Botanical description: A stout herb up to 1.5 m high, more or less hispid with long hairs; stems numerous, erect, usually unbranched, subquadragnular thickened at the nodes. Leaves in whorls of 6, the outer 2 the largest, oblong - lanceolate or oblanceolate, up to 18 cm long and 3.2 cm wide, with sharp yellow , auxiliary spines; the two outer leaves of each whorl larger and others much smaller.

Medicinal uses: In ayurveda, seeds and roots comprise the drug kolilakash, reputed remedies for arthritis. The bitter seeds are considered aphrodisiac and tonic and used as a uterine sedative for pregnant women and for treating diseases of the blood and biliousness. The seeds are given with sugar or milk in the treatment of impotence, gonorrhea and spermatorrhoea. A paste of seeds, mixed with buttermilk is given for diarrhea. A decoction of the root is used as a diuretic and to treat rheumatism. The leaves are considered oleaginous, tonic, aphrodisiac and hypnotic. Hygrophila schulli Family: Acanthaceae

Botanical description: A stout herb up to 1.5 m high, more or less hispid with long hairs; stems numerous, erect, usually unbranched, subquadragnular thickened at the nodes. Leaves in whorls of 6, the outer 2 the largest, oblong - lanceolate or oblanceolate, up to 18 cm long and 3.2 cm wide, with sharp yellow , auxiliary spines; the two outer leaves of each whorl larger and others much smaller.

Medicinal uses: hi ayurveda, seeds and roots comprise the drug kolilakash, reputed remedies for arthritis. The bitter seeds are considered aphrodisiac and tonic and used as a uterine sedative for pregnant women and for treating diseases of the blood and biliousness. The seeds are given with sugar or milk in the treatment of impotence, gonorrhea and spermatorrhoea. A paste of seeds, mixed with buttermilk is given for diarrhea. A decoction of the root is used as a diuretic and to treat rheumatism. The leaves are considered oleaginous, tonic, aphrodisiac and hypnotic. They are used to treat diarrhea, dysentery, thirst, urinary calculi and urinary discharges, diseases of the eyes, pains, ascites and abdominal troubles, anemia and constipation. Coϊocasia esculenta Family: Araceae

Medicinal properties and uses: Tubers consumed boiled or fried. Young leaves eaten like spinach, also consumed when bleached. Juice of the petioles used as an astringent and styptic. Taro mucilage may be used as a size for impermeable paper. Tubers may be used for production of industrial alcohol. Taro flour can be used for soups and gruels, gravies and puddings. Taro-malt, prepared from flour, is good foods for infants and invalids. Cuminum cyniinum Family: Umbelliferae/Apiaceae

Medicinal properties and uses: Fruits used as a condiment in curry powders and for flavoring dishes. They are considered carminative, stomachic and astringent, useful in dyspepsia and diarrhea. Yield an essential oil used for flavoring liqueurs and cordials, also in perfumery. Besides the volatile oil, fruits contain also fixed oil with strong aromatic flavor.

Apium graveolens Family: Umbelliferae/Apiaceae

Medicinal properties and uses: Leaves used in salads and soups. Cremocarps (fruits) are used as spice. They are stimulant, carminative, sedative and nervine tonic, decoction used in rheumatism. Fruits yield an essential oil, used as a spasmodic and nervine stimulant. It probably acts as an intestinal antiseptic and has been found useful in rheumatoid arthritis. Roots are used as diuretic. Allium cepa Family: Alliaceae

Botanical Description: Onion are a popular vegetable, also used for flavouring and pickling. Bulbs as well as fresh herb yield an essential oil.

Medicinal properties and uses: Onions considered stimulant, diuretic and expectorant, used against flatulence and dysentery. Roasted onions are applied as poultice Allium sativum Family: Alliaceae

Botanical Description: Bulbs consisting of cloves, used as a spice and condiment.

Medicinal Properties and usesBulbs Preparation of garlic are used in pulmonary phthisis, gangrene of the lungs, and whooping cough. Laryngeal tuberculosis, lupus, and duodenal ulcers are treated by garlic juices. Cloves also used for flatulence, colic, and atonic dyspepsia. Juice is applied in skin troubles and used as eardrops, it is used diluted with water as a vulnerary.

The following examples are given by way of illustration of the present invention and should not be construed to limit the scope of present invention.

Example 1

FORMULATIONS

Fl

Example 2

Blood pressure recording

Blood pressure (Systolic and diastolic) and pulse rate were recorded after 1 ^st and 2 ^nd week smoke exposure using a tail cuff blood pressure recorder (UGO Basile, Model no 58500; Comerio-varese, Italy). Rats were acclimatized to heating chamber (29-30 oC) for 30 min before recording the blood pressure (between 8. 30 and 10.30 AM), in order to cause a sufficient vasodilatation in the caudal artery. Three recordings were measured for each rat and the average was calculated.

Table 1: Body weight, systolic, diastolic pressure and pulse rate of smoke exposure in rats

The result explains that a change in the vital parameters on the blood pressure and pulse rate. This may be due to the reduction in the intake of the food during the course of exposure of the smoke.

Table 2: Body weight, systolic, diastolic pressure and pulse rate of smoke exposure in rats

The result explains that there is a change in the vital parameters on the blood pressure and pulse rate. However, there is a tendency in reduction of the body weight. This may be due to the reduction in the intake of the food during the course of exposure of the smoke.

Advantage:

1. The present formulation is effective in controlling of body weight.

2. It is also useful to remove stress, spreads fragrance or good aroma in surrounding.

3. It helps in improving the digestion and evacuation of bowel and also provides vitality and energy.