Title:
FUNCTIONAL NANOPARTICLES
Document Type and Number:
WIPO Patent Application WO/2016/167327
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an easily obtained formulation having exceptional functionality such as solvent dispersibility and percutaneous absorptivity of an active ingredient. The present invention pertains to functional nanoparticles including an active substance, the functional nanoparticles being dispersed in microparticles that include a readily water-soluble solute, and/or being present on the surface of the microparticles. The functional nanoparticles can be obtained by mixing immediately before spraying a liquid in which a readily water-soluble solute is dissolved in water and a liquid in which the active substance is dissolved in a solvent via separate flow paths, subsequently spraying the mixed liquid while the same is in a liquid-fine-particle state by using a pressurized gas, and removing the water and solvent through vaporization.
Inventors:
IMOTO TAKAYUKI (JP)
HATANAKA DAISUKE (JP)
HATANAKA DAISUKE (JP)
Application Number:
PCT/JP2016/062036
Publication Date:
October 20, 2016
Filing Date:
April 14, 2016
Export Citation:
Assignee:
NISSAN CHEMICAL IND LTD (JP)
International Classes:
A61K9/14; A61K8/02; A61K8/19; A61K8/34; A61K8/73; A61K31/405; A61K31/728; A61K33/44; A61K47/10; A61K47/36; A61P17/00; A61Q19/00; B82Y5/00
Foreign References:
| JP2009113169A | 2009-05-28 | |||
| JP2006524238A | 2006-10-26 | |||
| JP2002308728A | 2002-10-23 | |||
| JP2010116358A | 2010-05-27 | |||
| JP2004292398A | 2004-10-21 |
Other References:
AMI OMATA ET AL.: "Hyaluronic acid Nano Ryushi no Chosei to Hifu Shintosei", JAPANESE SOCIETY FOR BIOMATERIALS SYMPOSIUM 2012 YOKOSHU, 26 November 2012 (2012-11-26), pages PI33
Attorney, Agent or Firm:
TSUKUNI & ASSOCIATES et al. (JP)
Patent business corporation Tsukuni (JP)
Patent business corporation Tsukuni (JP)
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