Title:
FUNCTIONALIZED DIBLOCK COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/063206
Kind Code:
A1
Abstract:
The present application relates to the field of organic chemistry and polymer chemistry, and in particular to a functionalized diblock copolymer, a preparation method therefor and a use thereof. The present application provides a functionalized diblock copolymer, and a chemical structural formula of the functionalized diblock copolymer is as shown in formula I. The functionalized diblock copolymer or polymer particle provided in the present application can be widely applied to the fields of tumor images, tumor treatment, and the like; the present invention has good safety, so that rapid and adjustable (by changing the number of functional groups) degradation and removal of polymers under acidic conditions are achieved; the present invention also has an excellent-specificity high-quality image imaging effect at a target site, has the characteristics of high signal-noise ratio, clear boundary, long half-life period, and the like, and solves the problem of a fluorescence imaging technology in real-time intraoperative navigation. Thus, the present invention has good industrial prospects.
Inventors:
ZHOU CHUN (CN)
YE ZHENXING (CN)
LU CHENHONG (CN)
YE ZHENXING (CN)
LU CHENHONG (CN)
Application Number:
PCT/CN2021/120152
Publication Date:
March 31, 2022
Filing Date:
September 24, 2021
Export Citation:
Assignee:
INNOVATINGBIO SHANGHAI CO LTD (CN)
International Classes:
C08G79/04; A61K47/34; A61K49/00; C09K11/06
Foreign References:
| CN112142986A | 2020-12-29 | |||
| CN104387591A | 2015-03-04 | |||
| CN103421195A | 2013-12-04 | |||
| CN105213348A | 2016-01-06 | |||
| CN103055321A | 2013-04-24 | |||
| US20140308363A1 | 2014-10-16 |
Attorney, Agent or Firm:
J.Z.M.C. PATENT AND TRADEMARK LAW OFFICE (CN)
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