Title:
FUSED BICYCLIC COMPOUND AND USE THEREOF IN MEDICINE
Document Type and Number:
WIPO Patent Application WO/2018/233553
Kind Code:
A1
Abstract:
Disclosed are a fused bicyclic compound and the use thereof in a medicine, particularly a novel fused bicyclic compound used as an ASK1 activity regulator and a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the use of the compound in the preparation of a medicine for treating a disease and/or condition regulated by ASK1. Also disclosed are a pharmaceutical composition comprising the compound and a method for treating a disease and/or condition regulated by ASK1 by using the compound or the pharmaceutical composition thereof.
Inventors:
PAN SHENGQIANG (CN)
MA FACHENG (CN)
ZHANG YINGXUN (CN)
XIONG SHAOHUI (CN)
YANG XINYE (CN)
WANG XIAOJUN (CN)
ZHANG YINGJUN (CN)
MA FACHENG (CN)
ZHANG YINGXUN (CN)
XIONG SHAOHUI (CN)
YANG XINYE (CN)
WANG XIAOJUN (CN)
ZHANG YINGJUN (CN)
Application Number:
PCT/CN2018/091392
Publication Date:
December 27, 2018
Filing Date:
June 15, 2018
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D471/04; A61K31/437; A61P9/00; A61P25/28; A61P29/00; A61P37/00
Domestic Patent References:
WO2008016131A1 | 2008-02-07 | |||
WO2016025474A1 | 2016-02-18 |
Foreign References:
CN101878212A | 2010-11-03 | |||
CN102482257A | 2012-05-30 | |||
CN102834393A | 2012-12-19 |
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