Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST
Document Type and Number:
WIPO Patent Application WO/2019/198692
Kind Code:
A1
Abstract:
The present invention relates to fused cyclic urea derivatives which have antagonistic activities against CRHR1 and/or CRHR2, and which are useful in the treatment or prevention of disorders and diseases in which CRHR1 and/or CRHR2 is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CRHR1 and/or CRHR2 is involved.

Inventors:
OHMI MASASHI (JP)
MATSUSHITA TAKESHI (JP)
ANDO KAZUO (JP)
YAMAGUCHI RYUICHI (JP)
FUKUMOTO YUTAKA (JP)
MAGARA RYOHEI (JP)
YAMAGISHI TATSUYA (JP)
TAKEFUJI MIKITO (JP)
Application Number:
JP2019/015392
Publication Date:
October 17, 2019
Filing Date:
April 09, 2019
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
RAQUALIA PHARMA INC (JP)
UNIV NAGOYA NAT UNIV CORP (JP)
International Classes:
C07D235/26; A61K31/4184; A61K31/437; A61K31/4375; A61K31/4439; A61K31/4709; A61K31/4725; A61K31/497; A61K31/4985; A61K31/501; A61K31/506; A61K31/517; A61K31/519; A61K31/5377; A61K31/5383; A61P1/00; A61P9/00; A61P25/00; A61P29/00; A61P43/00; C07D401/12; C07D401/14; C07D403/12; C07D405/14; C07D413/14; C07D417/14; C07D471/04; C07D487/04; C07D491/107; C07D498/04
Domestic Patent References:
WO2011092293A22011-08-04
Foreign References:
JP2007161585A2007-06-28
JP2004533465A2004-11-04
JP2008517060A2008-05-22
Other References:
BECK, J. P . ET AL.: "PURIN-8-ONES AS CORTICOTROPIN-RELEASING HORMONE (CRH-R1) RECEPTOR ANTAGONISTS", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 9, no. 7, 1999, pages 967 - 972, XP004162567, DOI: 10.1016/S0960-894X(99)00108-0
Attorney, Agent or Firm:
IWATANI, Ryo (JP)
Download PDF: