FUSED HETEROCYCLIC BIARYL BENZYL ALCOHOL COMPOUND, PREPARATION METHOD, AND USE

Title:

FUSED HETEROCYCLIC BIARYL BENZYL ALCOHOL COMPOUND, PREPARATION METHOD, AND USE

Document Type and Number:

WIPO Patent Application WO/2020/063976

Kind Code:

A1

Abstract:

Provided are a fused heterocyclic biaryl benzyl alcohol compound, a preparation method, and use. The fused heterocyclic biaryl benzyl alcohol compound is as represented by formula (IA), has good inhibition activity for a BRD enzyme, and is quite excellent in inhibition activity for BRD/c-Myc-related cell proliferation.

Inventors:

WAN HUIXIN (CN)
PAN JIANFENG (CN)
MA JINGUI (CN)

Application Number:

PCT/CN2019/109143

Publication Date:

April 02, 2020

Filing Date:

September 29, 2019

Export Citation:

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Assignee:

RUDONG RINGENE PHARMACEUTICALS CO LTD (CN)

International Classes:

C07D471/14; A61K31/437; A61K31/4427; A61K31/4985; A61K31/519; A61P1/00; A61P1/16; A61P3/10; A61P7/06; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P15/00; A61P17/00; A61P17/06; A61P17/14; A61P19/06; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P37/00; A61P37/02; A61P37/06; C07D487/14

Domestic Patent References:

WO2017177955A1	2017-10-19
WO2015095492A1	2015-06-25

Foreign References:

CN105164135A

2015-12-16

Attorney, Agent or Firm:

SHANGHAI BESHINING LAW OFFICE (CN)

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