Title:
FUSED HETEROCYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2023/104111
Kind Code:
A1
Abstract:
The present disclosure describes antagonists of the enzyme. The present disclosure provides compounds having a structure set forth in Formula (VI), (VII), (VII-1) or (VIII), the stereoisomer or pharmaceutically acceptable salts, solvates and prodrugs thereof. Further provided are uses of the compounds of Formula (VI), (VII), (VII-1) or (VIII) in treating cancers.
Inventors:
HAO XIAOLIN (US)
LEI YONGHUA (CN)
LEI YONGHUA (CN)
Application Number:
PCT/CN2022/137307
Publication Date:
June 15, 2023
Filing Date:
December 07, 2022
Export Citation:
Assignee:
NANJING ZENSHINE PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D405/04; A61K31/352; A61K31/4433; A61P35/00; C07D471/04
Domestic Patent References:
| WO2004016607A1 | 2004-02-26 | |||
| WO2022251482A1 | 2022-12-01 | |||
| WO2022235574A1 | 2022-11-10 | |||
| WO2022235575A1 | 2022-11-10 | |||
| WO2021202964A1 | 2021-10-07 | |||
| WO2011051704A1 | 2011-05-05 |
Attorney, Agent or Firm:
WU, FENG & ZHANG (CN)
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