Title:
FUSED HETEROCYCLIC DERIVATIVES
Document Type and Number:
WIPO Patent Application WO/2022/253255
Kind Code:
A1
Abstract:
The application describes fused heterocycle derivative compounds, pharmaceutical compositions comprising these compounds, chemical processes for preparing these compounds and their use in the treatment of diseases associated with HBV infection.
Inventors:
LU CHUNLIANG (CN)
DENG GANG (CN)
LIU LIANZHU (CN)
LI XIAOYU (CN)
LIU ZHIGUO (CN)
TANG BINGQING (CN)
CAI WEI (CN)
PLUNKETT SHANE (US)
PYE PHILIP JAMES (US)
DERATT LINDSEY GRAHAM (US)
RABOISSON PIERRE JEAN-MARIA BERNARD (BE)
JACOBY EDGAR (BE)
GROSSE SANDRINE CÉLINE (BE)
CHENG ZHANLING (CN)
VANDYCK KOEN (BE)
JONCKERS TIM HUGO MARIA (BE)
KUDUK SCOTT D (US)
DENG GANG (CN)
LIU LIANZHU (CN)
LI XIAOYU (CN)
LIU ZHIGUO (CN)
TANG BINGQING (CN)
CAI WEI (CN)
PLUNKETT SHANE (US)
PYE PHILIP JAMES (US)
DERATT LINDSEY GRAHAM (US)
RABOISSON PIERRE JEAN-MARIA BERNARD (BE)
JACOBY EDGAR (BE)
GROSSE SANDRINE CÉLINE (BE)
CHENG ZHANLING (CN)
VANDYCK KOEN (BE)
JONCKERS TIM HUGO MARIA (BE)
KUDUK SCOTT D (US)
Application Number:
PCT/CN2022/096525
Publication Date:
December 08, 2022
Filing Date:
June 01, 2022
Export Citation:
Assignee:
JANSSEN SCIENCES IRELAND UNLIMITED CO (IE)
JOHNSON & JOHNSON CHINA INVEST LTD (CN)
JOHNSON & JOHNSON CHINA INVEST LTD (CN)
International Classes:
A61P31/20; A61K31/4985; C07D471/14
Domestic Patent References:
| WO2020243135A1 | 2020-12-03 | |||
| WO2018005883A1 | 2018-01-04 | |||
| WO2022116997A1 | 2022-06-09 |
Foreign References:
| CN2021097848W | 2021-06-02 | |||
| CN2022090237W | 2022-04-29 |
Other References:
"Remington's Pharmaceutical Sciences", 1985, MACK PUBLISHING CO.
HUGHES, S.A. ET AL., LANCET, vol. 378, 2011, pages 73 - 85
HOLFORDSCHEINER, CLIN. PHARMACOKINET., vol. 6, pages 429 - 453
LOEWEMUISCHNEK, ARCH. EXP. PATHOL PHARMACOL., vol. 114, 1926, pages 313 - 326
CHOUTALALAY, ADV. ENZYME REGUL., vol. 22, 1984, pages 27 - 55
"Van Nostrand's Encyclopedia of Chemistry", 2005, pages: 261
G.S. PAULEKUHN ET AL.: "Trends in Active Pharmaceutical Ingredient Salt Selection based on Analysis of the Orange Book Database", J. MED. CHEM., vol. 50, 2007, pages 6665 - 72, XP055536811, DOI: 10.1021/jm701032y
S.M. BERGE ET AL.: "Pharmaceutical Salts", J PHARM SCI., vol. 66, 1977, pages 1 - 19, XP002675560, DOI: 10.1002/jps.2600660104
"Handbook of Pharmaceutical Salts, Properties, Selection, and Use", 2002, WILEY-VCH
HUGHES, S.A. ET AL., LANCET, vol. 378, 2011, pages 73 - 85
HOLFORDSCHEINER, CLIN. PHARMACOKINET., vol. 6, pages 429 - 453
LOEWEMUISCHNEK, ARCH. EXP. PATHOL PHARMACOL., vol. 114, 1926, pages 313 - 326
CHOUTALALAY, ADV. ENZYME REGUL., vol. 22, 1984, pages 27 - 55
"Van Nostrand's Encyclopedia of Chemistry", 2005, pages: 261
G.S. PAULEKUHN ET AL.: "Trends in Active Pharmaceutical Ingredient Salt Selection based on Analysis of the Orange Book Database", J. MED. CHEM., vol. 50, 2007, pages 6665 - 72, XP055536811, DOI: 10.1021/jm701032y
S.M. BERGE ET AL.: "Pharmaceutical Salts", J PHARM SCI., vol. 66, 1977, pages 1 - 19, XP002675560, DOI: 10.1002/jps.2600660104
"Handbook of Pharmaceutical Salts, Properties, Selection, and Use", 2002, WILEY-VCH
Attorney, Agent or Firm:
NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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