Fused pentacyclic polyethers - UNIV NORTH CAROLINA AT WILMING

Title:

Fused pentacyclic polyethers

Document Type and Number:

WIPO Patent Application WO2005028481

Kind Code:

A8

Abstract:

Disclosed are polycyclic polyether compounds of formula: (I) and pharmaceutical compositions comprising such compounds. Wherein R, OR₁ and R₂ are as defined herein. Also disclosed are methods of regulating mucus clearance in a cell, and methods of treating decreased mucus clearance or mucociliary dysfunction.

Inventors:

BADEN DANIEL G (US)
ABRAHAM WILLIAM M (US)
BOURDELAIS ANDREA J (US)

Application Number:

PCT/US2004/030535

Publication Date:

June 01, 2006

Filing Date:

September 20, 2004

Export Citation:

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Assignee:

UNIV NORTH CAROLINA AT WILMING (US)
BADEN DANIEL G (US)
ABRAHAM WILLIAM M (US)
BOURDELAIS ANDREA J (US)

International Classes:

A61K31/35; A61K31/353; A61K31/42; A61K31/7072; C07D493/04; C07D493/14; C07D493/22; C07H19/04

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