Title:
FUSED RING COMPOUND AS NAV1.8 INHIBITOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/121805
Kind Code:
A1
Abstract:
The present invention provides a fused ring compound as a sodium channel blocker and a use thereof. The fused ring compound has inhibitory activity on a sodium ion channel Nav1.8, and can be used as a drug for extensive pain treatment.
Inventors:
LIU TING (CN)
FANG QUN (CN)
ZHENG YANG (CN)
KE ZUNHONG (CN)
FANG QUN (CN)
ZHENG YANG (CN)
KE ZUNHONG (CN)
Application Number:
PCT/CN2021/135469
Publication Date:
June 16, 2022
Filing Date:
December 03, 2021
Export Citation:
Assignee:
CHENGDU KANGHONG PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D401/04; A61K31/44; A61P29/00; C07D413/12; C07D417/04; C07D417/14; C07D471/10; C07D487/04; C07D491/04; C07D495/04
Domestic Patent References:
| WO2020092187A1 | 2020-05-07 | |||
| WO2020092667A1 | 2020-05-07 |
Foreign References:
| CN101466665A | 2009-06-24 | |||
| CN112457294A | 2021-03-09 |
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