FUSION PROTEIN CAPABLE OF SELF-ASSEMBLY BY COMPRISING PEPTIDE TAG OF WHICH MAIN AMINO ACIDS ARE CHARGED AMINO ACIDS, AND METHOD FOR PURIFYING RECOMBINANT PROTEIN BY USING SAME

Title:

FUSION PROTEIN CAPABLE OF SELF-ASSEMBLY BY COMPRISING PEPTIDE TAG OF WHICH MAIN AMINO ACIDS ARE CHARGED AMINO ACIDS, AND METHOD FOR PURIFYING RECOMBINANT PROTEIN BY USING SAME

Document Type and Number:

WIPO Patent Application WO/2024/071970

Kind Code:

A1

Abstract:

The present invention relates to: a fusion polypeptide comprising a His tag, and a peptide tag of which the main amino acids are charged amino acids; a fusion protein in which the fusion polypeptide and a target protein are fused; and a method for purifying the target protein by using same. Since the fusion polypeptide has the ability to induce self-assembly by being fused with the target protein, the target protein purification method using same enables the isolation and purification of the target protein merely through very simple processes such as centrifugation or filtration.

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Inventors:

KIM DAE HEON (KR)
NA YUN JEONG (KR)
KIM JONGHAK (KR)
CHOI SEON (KR)

Application Number:

PCT/KR2023/014780

Publication Date:

April 04, 2024

Filing Date:

September 26, 2023

Export Citation:

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Assignee:

CCRIPO INC (KR)

International Classes:

C07K7/06; C07K1/34; C07K14/00; C07K14/435; C12N15/62

Attorney, Agent or Firm:

YOU ME PATENT AND LAW FIRM (KR)

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