FUSION PROTEIN COMPRISING PEPTIDE TAG HAVING MAIN AMINO ACIDS COMPOSED OF CHARGED AND POLAR AMINO ACIDS AND FORMING SELF-ASSEMBLY, AND METHOD FOR PURIFYING RECOMBINANT PROTEIN USING SAME

Title:

FUSION PROTEIN COMPRISING PEPTIDE TAG HAVING MAIN AMINO ACIDS COMPOSED OF CHARGED AND POLAR AMINO ACIDS AND FORMING SELF-ASSEMBLY, AND METHOD FOR PURIFYING RECOMBINANT PROTEIN USING SAME

Document Type and Number:

WIPO Patent Application WO/2024/071964

Kind Code:

A1

Abstract:

The present invention relates to: a fusion polypeptide in which a His tag is fused with a peptide tag having main amino acids composed of charged and polar amino acids; a fusion protein in which the fusion polypeptide is fused with a target protein; and a target protein purification method using the same. Since the peptide tag is fused with the target protein and thus has the ability to induce the formation of a self-assembly, a target protein purification method using same can be used to isolate and purify the target protein by using only a very simple method such as centrifugation or filtration.

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Inventors:

KIM DAE HEON (KR)
NA YUN JEONG (KR)
KIM JONGHAK (KR)
CHOI SEON (KR)

Application Number:

PCT/KR2023/014773

Publication Date:

April 04, 2024

Filing Date:

September 26, 2023

Export Citation:

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Assignee:

CCRIPO INC (KR)

International Classes:

C07K7/06; C07K1/34; C07K7/08; C07K14/435; C12N15/62

Attorney, Agent or Firm:

YOU ME PATENT AND LAW FIRM (KR)

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