Title:
FUSION PROTEIN, KIT AND CHIP-SEQ DETECTION METHOD
Document Type and Number:
WIPO Patent Application WO/2019/153851
Kind Code:
A1
Abstract:
A fusion protein, a kit and a CHIP-seq detection method. The fusion protein comprises a Tn5 transposase and an Fc binding protein. The kit comprises said fusion protein and other auxiliary detection reagents. Said method uses said fusion protein or kit to perform the CHIP-seq detection method. Said fusion protein, kit and method can improve library construction efficiency during CHIP-seq detection and reduce library background, thereby improving the accuracy of the CHIP-seq detection method and simplifying the experimental flow of CHIP-seq.
Inventors:
HE AIBIN (CN)
AI SHANSHAN (CN)
LUO YINGJIE (CN)
AI SHANSHAN (CN)
LUO YINGJIE (CN)
Application Number:
PCT/CN2018/118432
Publication Date:
August 15, 2019
Filing Date:
November 30, 2018
Export Citation:
Assignee:
UNIV BEIJING (CN)
International Classes:
C07K19/00; C12N9/12; C12Q1/6804; C12Q1/6869
Foreign References:
| CN108285494A | 2018-07-17 | |||
| CN108219006A | 2018-06-29 | |||
| CN106507677A | 2017-03-15 | |||
| US20070009937A1 | 2007-01-11 | |||
| CN107674870A | 2018-02-09 | |||
| CN105754995A | 2016-07-13 | |||
| CN107841533A | 2018-03-27 |
Attorney, Agent or Firm:
CHOFN INTELLECTUAL PROPERTY (CN)
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