Title:
FUSION PROTEINS FOR SPECIFIC TREATMENT OF CANCER AND AUTO-IMMUNE DISEASES
Document Type and Number:
WIPO Patent Application WO2002079222
Kind Code:
A3
Abstract:
The invention relates to the field of apoptosis. The invention provides novel therapeutic substances, for example novel therapeutic (non) viral vectors or proteinaceous compounds that contain apoptin in conjunction with cytotoxic agents, especially in those cases when cells are derailed such as cancer-autoimmune-derived cells.
Inventors:
NOTEBORN MATHIEU HUBERTUS MARI (NL)
RENES JOHAN (NL)
ZHANG YING-HUI (NL)
RENES JOHAN (NL)
ZHANG YING-HUI (NL)
Application Number:
PCT/NL2002/000204
Publication Date:
May 08, 2003
Filing Date:
March 28, 2002
Export Citation:
Assignee:
LEADD BV (NL)
NOTEBORN MATHIEU HUBERTUS MARI (NL)
RENES JOHAN (NL)
ZHANG YING-HUI (NL)
NOTEBORN MATHIEU HUBERTUS MARI (NL)
RENES JOHAN (NL)
ZHANG YING-HUI (NL)
International Classes:
A61P19/02; A61P35/00; C07K14/01; C07K14/47; (IPC1-7): C12N15/62; C07K14/01; C12N9/12; A61K47/48; A61K38/16; A61K38/45; A61P35/00; A61P19/02
Domestic Patent References:
| WO2000041497A2 | 2000-07-20 | |||
| WO1998046760A1 | 1998-10-22 | |||
| WO1999008108A1 | 1999-02-18 | |||
| WO1996041191A1 | 1996-12-19 | |||
| WO2002085305A2 | 2002-10-31 |
Foreign References:
| EP1186665A1 | 2002-03-13 | |||
| EP1188832A1 | 2002-03-20 |
Other References:
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; April 1998 (1998-04-01), VAN DER EB M M ET AL: "Severe hepatic dysfunction after adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene and ganciclovir administration.", XP002229399, Database accession no. PREV199800256147
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1 May 1999 (1999-05-01), GOOSSENS PAULIEN H ET AL: "Feasibility of adenovirus-mediated nonsurgical synovectomy in collagen-induced arthritis-affected rhesus monkeys.", XP002229400, Database accession no. PREV199900277375
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1989, LAFYATIS R ET AL: "ANCHORAGE-INDEPENDENT GROWTH OF SYNOVIOCYTES FROM ARTHRITIC AND NORMAL JOINTS STIMULATION BY EXOGENOUS PLATELET-DERIVED GROWTH FACTOR AND INHIBITION BY TRANSFORMING GROWTH FACTOR-BETA AND RETINOIDS", XP002229401, Database accession no. PREV198987122407
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1 May 1999 (1999-05-01), GOOSSENS PAULIEN H ET AL: "Feasibility of adenovirus-mediated nonsurgical synovectomy in collagen-induced arthritis-affected rhesus monkeys.", XP002229400, Database accession no. PREV199900277375
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1989, LAFYATIS R ET AL: "ANCHORAGE-INDEPENDENT GROWTH OF SYNOVIOCYTES FROM ARTHRITIC AND NORMAL JOINTS STIMULATION BY EXOGENOUS PLATELET-DERIVED GROWTH FACTOR AND INHIBITION BY TRANSFORMING GROWTH FACTOR-BETA AND RETINOIDS", XP002229401, Database accession no. PREV198987122407
Download PDF:
Previous Patent: SAPOGENIN DERIVATIVES, THEIR SYNTHESIS AND USE
Next Patent: COVALENTLY REACTIVE TRANSITION STATE ANALOGS AND METHODS OF USE THEREOF
Next Patent: COVALENTLY REACTIVE TRANSITION STATE ANALOGS AND METHODS OF USE THEREOF