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Patent Searching and Data


Title:
GADOBUTROL INTERMEDIATE AND GADOBUTROL PRODUCTION METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2019/045436
Kind Code:
A1
Abstract:
Disclosed are: an intermediate capable of high-purity synthesis of gadobutrol which can be used as an MRI contrast agent; and a gadobutrol production method using same. The gadobutrol intermediate is represented by Chemical Formula 2 in the specification.

Inventors:
LEE JAE YONG (KR)
LEE JONG SOO (KR)
KANG BYUNG KYU (KR)
LEE SANG OH (KR)
LEE BYUONG WOO (KR)
YUN DAE MYOUNG (KR)
BANG JAE HUN (KR)
CHOI KYUNG SEOK (KR)
Application Number:
PCT/KR2018/009956
Publication Date:
March 07, 2019
Filing Date:
August 29, 2018
Export Citation:
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Assignee:
ENZYCHEM LIFESCIENCES CORP (KR)
International Classes:
C07D257/02; A61K49/10
Domestic Patent References:
WO2011151347A12011-12-08
WO1998055467A11998-12-10
WO2012143355A12012-10-26
WO2001058988A12001-08-16
WO1998056776A11998-12-17
WO1999005145A11999-02-04
WO2012143355A12012-10-26
WO2011151347A12011-12-08
Foreign References:
KR20140035911A2014-03-24
KR20160079460A2016-07-06
KR20160056648A2016-05-20
US5539105A1996-07-23
US5980864A1999-11-09
US5962679A1999-10-05
Other References:
PLATZEK, J.: "Synthesis and structure of a new macrocyclic polyhydroxylated gadolinium chelate used as a contrast agent for magnetic resonance imaging", INORGANIC CHEMISTRY, 1997, pages 6086 - 6093, XP002199426, DOI: 10.1021/ic970123t
See also references of EP 3677574A4
Attorney, Agent or Firm:
SHINWOO PATENT & LAW FIRM (KR)
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