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Title:
GENE ENCODING FATTY ACID ELONGASE, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2010/147138
Kind Code:
A1
Abstract:
A novel fatty acid elongase is provided. Disclosed are: a fatty acid elongase involved in a fatty acid chain extension reaction; a polynucleotide encoding the fatty acid elongase; and others. Specifically disclosed are: a polynucleotide comprising the nucleotide sequence depicted in SEQ ID NO:1 or SEQ ID NO:4; a polynucleotide encoding a protein comprising the amino acid sequence depicted in SEQ ID NO:2; an expression vector and a transformant, each of which carries the polynucleotide; a process for producing a food or the like using the transformant; a food produced by the process; a method for evaluating or selecting a fat-producing bacterium of interest; and others.

Inventors:
OCHIAI MISA (JP)
SHIMIZU SAKAYU (JP)
SAKURADANI EIJI (JP)
Application Number:
PCT/JP2010/060186
Publication Date:
December 23, 2010
Filing Date:
June 16, 2010
Export Citation:
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Assignee:
SUNTORY HOLDINGS LTD (JP)
OCHIAI MISA (JP)
SHIMIZU SAKAYU (JP)
SAKURADANI EIJI (JP)
International Classes:
C12N15/00; A23D9/02; A61K31/7088; A61K31/713; A61K36/06; A61P1/14; A61P25/18; A61P35/00; A61P43/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/00; C12N15/09; C12P7/64; C12Q1/02; C12Q1/04; C12Q1/68
Foreign References:
JP2006262778A2006-10-05
JP2009512437A2009-03-26
JP2008073030A2008-04-03
JP2004097134A2004-04-02
Other References:
SAKURADANI E ET AL.: "Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4.", APPL MICROBIOL BIOTECHNOL., vol. 84, no. 4, September 2009 (2009-09-01), pages 709 - 716, XP019737724, DOI: doi:10.1007/s00253-009-1999-3
KAWASHIMA H ET AL.: "Inhibitory effects of alkyl gallate and its derivatives on fatty acid desaturation.", BIOCHIM BIOPHYS ACTA, vol. 1299, no. 1, 1996, pages 34 - 38
EIJI SAKURADANI ET AL.: "Production of functional lipids by microorganisms: arachidonic acid and related polyunsaturated fatty acids", PROTEIN, NUCLEIC ACID AND ENZYME, vol. 54, no. 6, May 2009 (2009-05-01), pages 725 - 734
"59th Annual Meeting of the Society for Biotechnology, Japan", 2007, article KUNI ITO ET AL.: "Expression of elongase gene from microalgae Pavlova sp. in oleaginous fungus Mortierella alpina 1S-4", pages: 110 - 3D12-1
Attorney, Agent or Firm:
KOBAYASHI, Hiroshi et al. (JP)
Kobayashi 浩 (JP)
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