Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
GENE EXPRESSION MARKERS FOR BREAST CANCER PROGNOSIS
Document Type and Number:
WIPO Patent Application WO2004065583
Kind Code:
A3
Abstract:
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.

Inventors:
COBLEIGH MELODY A (US)
SHAK STEVE (US)
BAKER JOFFRE B (US)
CRONIN MAUREEN T (US)
Application Number:
US2004000985W
Publication Date:
March 03, 2005
Filing Date:
January 14, 2004
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
GENOMIC HEALTH, INC.
RUSH UNIVERSITY MEDICAL CENTER
COBLEIGH, MELODY, A.
SHAK, STEVE
BAKER, JOFFRE, B.
CRONIN, MAUREEN, T.
International Classes:
B60G9/02; B60K17/04; C12N; (IPC1-7): C12Q1/68
Domestic Patent References:
WO2002010436A22002-02-07
WO2003078662A12003-09-25
WO2002046467A22002-06-13
WO2000055180A22000-09-21
WO2001075160A12001-10-11
WO2000055173A12000-09-21
WO2002059271A22002-08-01
Foreign References:
US6001583A1999-12-14
Other References:
SGROI D C ET AL: "IN VIVO GENE EXPRESSION PROFILE ANALYSIS OF HUMAN BREAST CANCER PROGRESSION", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 59, no. 22, 15 November 1999 (1999-11-15), pages 5656 - 5661, XP000994514, ISSN: 0008-5472
SAMUELS-LEV YARDENA ET AL: "ASPP proteins specifically stimulate the apoptotic function of p53", MOLECULAR CELL, vol. 8, no. 4, October 2001 (2001-10-01), pages 781 - 794, XP002202189, ISSN: 1097-2765
GUERIN M ET AL: "STRUCTURE AND EXPRESSION OF C-ERBB-2 AND EGF RECEPTOR GENES IN INFLAMMATORY AND NON-INFLAMMATORY BREAST CANCER: PROGNOSTIC SIGNIFICANCE", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 43, 1989, pages 201 - 208, XP002935671, ISSN: 0020-7136
MURRAY P A ET AL: "The prognostic significance of transforming growth factors in human breast cancer", BRITISH JOURNAL OF CANCER, vol. 67, no. 6, 1993, pages 1408 - 1412, XP008031811, ISSN: 0007-0920
SENS MARY ANN ET AL: "Metallothionein isoform 3 overexpression is associated with breast cancers having a poor prognosis", AMERICAN JOURNAL OF PATHOLOGY, vol. 159, no. 1, July 2001 (2001-07-01), pages 21 - 26, XP002285193, ISSN: 0002-9440
SCHORR K ET AL: "BCL-2 GENE FAMILY AND RELATED PROTEINS IN MAMMARY GLAND INVOLUTION AND BREAST CANCER", JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, PLENUM PRESS, NEW YORK, NY,, US, vol. 4, no. 2, April 1999 (1999-04-01), pages 153 - 164, XP000973885, ISSN: 1083-3021
VEER VAN 'T L J ET AL: "Gene expression profiling predicts clinical outcome of breast cancer", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 415, no. 6871, 31 January 2002 (2002-01-31), pages 530 - 536, XP002259781, ISSN: 0028-0836
BORRESEN-DALE A-L: "GENETIC PROFILING OF BREAST CANCER: FROM MOLECULAR PORTRAITS TO CLINICAL UTILITY", INTERNATIONAL JOURNAL OF BIOLOGICAL MARKERS, WICHTIG EDITORE, MILAN, IT, vol. 18, no. 1, 20 September 2002 (2002-09-20), pages 54 - 56, XP008036675, ISSN: 0393-6155
LEEK R D ET AL: "ASSOCIATION OF MACROPHAGE INFILTRATION WITH ANGIOGENESIS AND PROGNOSIS IN INVASIVE BREAST CARCINOMA", CANCER RESEARCH, AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD, US, vol. 56, 15 October 1996 (1996-10-15), pages 4625 - 4629, XP002056968, ISSN: 0008-5472
UENO T ET AL: "Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer.", CLINICAL CANCER RESEARCH : AN OFFICIAL JOURNAL OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH. AUG 2000, vol. 6, no. 8, August 2000 (2000-08-01), pages 3282 - 3289, XP002304930, ISSN: 1078-0432
FOROZAN FARAHNAZ ET AL: "Comparative genomic hybridization analysis of 38 breast cancer cell lines: A basis for interpreting complementary DNA microarray data", CANCER RESEARCH, vol. 60, no. 16, 15 August 2000 (2000-08-15), pages 4519 - 4525, XP002304931, ISSN: 0008-5472
RASCHELLA GIUSEPPE ET AL: "Expression of B-myb in neuroblastoma tumors is a poor prognostic factor independent from MYCN amplification", CANCER RESEARCH, vol. 59, no. 14, 15 July 1999 (1999-07-15), pages 3365 - 3368, XP002304932, ISSN: 0008-5472
CHENARD M-P ET AL: "HIGH LEVELS OF STROMELYSIN-3 CORRELATE WITH POOR PROGNOSIS IN PATIENTS WITH BREAST CARCINOMA", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 69, no. 6, 1996, pages 448 - 451, XP008036913, ISSN: 0020-7136
ENGEL G ET AL: "CORRELATION BETWEEN STROMELYSIN-3 MRNA LEVEL AND OUTCOME OF HUMAN BREAST CANCER", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 58, no. 6, 1994, pages 830 - 835, XP008036912, ISSN: 0020-7136
AHMAD A ET AL: "STROMELYSIN 3: AN INDEPENDENT PROGNOSTIC FACTOR FOR RELAPSE-FREE SURVIVAL IN NODE-POSITIVE BREAST CANCER AND DEMONSTRATION OF NOVEL BREAST CARCINOMA CELL EXPRESSION", AMERICAN JOURNAL OF PATHOLOGY, PHILADELPHIA, PA, US, vol. 152, no. 3, March 1998 (1998-03-01), pages 721 - 728, XP001073488, ISSN: 0002-9440
Download PDF: