Title:
GENE SIGNATURES ASSOCIATED WITH REJECTION OR RECURRENCE OF CANCER
Document Type and Number:
WIPO Patent Application WO/2012/129488
Kind Code:
A3
Abstract:
Methods and tools for assessing the prognosis for patients following treatment of primary tumors are provided. The methods involve identifying immune- or cancer-related genetic markers whose differential expression patterns at tumor lesions are indicative of either tumor recurrence or recurrence-free survival. The methods and tools of the invention assist physicians by providing objective decision-making tools for planning patient treatment protocols.
Inventors:
MANJILI MASOUD H (US)
KMIECIAK MACIEJ (US)
TOOR AMIR A (US)
IDOWU MICHAEL O (US)
BEAR HARRY D (US)
PAYNE KYLE K (US)
MARINCOLA FRANCESCO M (US)
WANG ENA (US)
KMIECIAK MACIEJ (US)
TOOR AMIR A (US)
IDOWU MICHAEL O (US)
BEAR HARRY D (US)
PAYNE KYLE K (US)
MARINCOLA FRANCESCO M (US)
WANG ENA (US)
Application Number:
PCT/US2012/030312
Publication Date:
December 27, 2012
Filing Date:
March 23, 2012
Export Citation:
Assignee:
UNIV VIRGINIA COMMONWEALTH (US)
MANJILI MASOUD H (US)
KMIECIAK MACIEJ (US)
TOOR AMIR A (US)
IDOWU MICHAEL O (US)
BEAR HARRY D (US)
PAYNE KYLE K (US)
MARINCOLA FRANCESCO M (US)
WANG ENA (US)
MANJILI MASOUD H (US)
KMIECIAK MACIEJ (US)
TOOR AMIR A (US)
IDOWU MICHAEL O (US)
BEAR HARRY D (US)
PAYNE KYLE K (US)
MARINCOLA FRANCESCO M (US)
WANG ENA (US)
International Classes:
C12Q1/68; G01N33/574
Domestic Patent References:
| WO2010003771A1 | 2010-01-14 |
Foreign References:
| US20110034347A1 | 2011-02-10 | |||
| US20060115832A1 | 2006-06-01 | |||
| US20090130678A1 | 2009-05-21 | |||
| US20100280105A1 | 2010-11-04 |
Attorney, Agent or Firm:
WHITHAM, Michael, E. et al. (Curtis Christofferson & Cook, P.C.,11491 Sunset Hills Road, Suite 34, Reston VA, US)
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