GENERAL-PURPOSE DEPROTECTING METHOD USING SULFUR OXIDE

Title:

GENERAL-PURPOSE DEPROTECTING METHOD USING SULFUR OXIDE

Document Type and Number:

WIPO Patent Application WO/2007/099894

Kind Code:

A1

Abstract:

An object is to provide a method for production of an industrially useful amine derivative safely and with high efficiency by employing a deprotecting technique which is applicable to any protected amine derivative for general purposes. Another object is to provide a deprotecting method applicable to any compound having a protecting group on a heteroatom. The objects can be achieved by reacting a compound having a protecting group on a heteroatom (including a protected amine derivative) with a sulfur oxide in a solvent to detach the protecting group. The methods are less likely to require a strong acid or base, are simpler, and require no complicated after-treatment, compared to conventional methods.

More Like This:

WO/2009/102043	METHOD FOR PRODUCING OPTICALLY ACTIVE 4-AMINO-3-(3,4-DICHLOROPHENYL)BUTAN-1-OL AND INTERMEDIATE THEREFOR
WO/2000/023608	PREPARATION OF AMINO ALCOHOLS
WO/2002/083659	DIAMINE, ACID DIANHYDRIDE, POLYIMIDE COMPOSITION HAVING REACTIVE GROUP OBTAINED THEREFROM, AND PROCESSES FOR PRODUCING THESE

Inventors:

AMANO SUSUMU (JP)
KAWASAKI HIROAKI (JP)
FUJII AKIO (JP)
MOROSHIMA TADASHI (JP)
MITSUDA MASARU (JP)
KINOSHITA KOICHI (JP)
UEDA YASUYOSHI (JP)

Application Number:

PCT/JP2007/053484

Publication Date:

September 07, 2007

Filing Date:

February 26, 2007

Export Citation:

Click for automatic bibliography generation Help

Assignee:

KANEKA CORP (JP)
AMANO SUSUMU (JP)
KAWASAKI HIROAKI (JP)
FUJII AKIO (JP)
MOROSHIMA TADASHI (JP)
MITSUDA MASARU (JP)
KINOSHITA KOICHI (JP)
UEDA YASUYOSHI (JP)

International Classes:

C07C213/02; C07B43/04; C07C211/27; C07C217/28; C07C229/28; C07C229/36; C07D207/16

Other References:

ONO M. AND ITOH I.: "A new deprotection method for levulinyl protecting groups under neutral conditions", CHEMISTRY LETTERS, 1988, pages 585 - 588, XP003016872
KARUPAIYAN K. ET AL.: "Synthesis of N1-unsubstituted beta-lactams: introducing N1-(1'-thiophenyl) benzyl as an N-protecting group", TETRAHEDRON LETTERS, vol. 38, no. 24, 1997, pages 4281 - 4284, XP004074811

Attorney, Agent or Firm:

KANEKA CORPORATION (Kita-ku Osaka-shi, Osaka, JP)

Download PDF:

View/Download PDF PDF Help

Previous Patent: VOICE-INPUTTING EAR MICROPHONE

Next Patent: IMPINGEMENT COOLING STRUCTURE