Title:
GENERATION OF NEURAL PROGENITOR CELLS FROM EMBRYONIC STEM CELLS OR INDUCED PLURIPOTENT STEM CELLS
Document Type and Number:
WIPO Patent Application WO/2022/110654
Kind Code:
A1
Abstract:
The present application provides methods and cell culture media for generating neural progenitor cells (NPCs), particularly human neural progenitor cells (hNPCs), from either embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs). The NPCs are particularly suitable for pre-clinical and clinical use.
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Inventors:
FAN JING (CN)
WANG ANXIN (CN)
REN FANG (CN)
LIU QIANYUN (CN)
ZOU TAN (CN)
WANG ANXIN (CN)
REN FANG (CN)
LIU QIANYUN (CN)
ZOU TAN (CN)
Application Number:
PCT/CN2021/092702
Publication Date:
June 02, 2022
Filing Date:
May 10, 2021
Export Citation:
Assignee:
ZHEJIANG HUODE BIOENGINEERING COMPANY (CN)
International Classes:
C12N5/00; C12N5/0797
Foreign References:
| CN108884444A | 2018-11-23 | |||
| CN108048400A | 2018-05-18 | |||
| CN1997733A | 2007-07-11 | |||
| CN103415614A | 2013-11-27 |
Other References:
MURATORE CHRISTINA R., SRIKANTH PRIYA, CALLAHAN DANA G., YOUNG-PEARSE TRACY L.: "Comparison and Optimization of hiPSC Forebrain Cortical Differentiation Protocols", PLOS ONE, vol. 9, no. 8, pages e105807, XP055934881, DOI: 10.1371/journal.pone.0105807
TAKAFUMI WATAYA, KEIKO MUGURUMA, YOSHIKI SASAI: "Human Pluripotent Stem Cell and Neural Differentiation", BRAIN AND NERVE , vol. 60, no. 10, 31 October 2008 (2008-10-31), JP , pages 1165 - 1172, XP009536838, ISSN: 1881-6096, DOI: 10.11477/mf.1416100360
TAKAFUMI WATAYA, KEIKO MUGURUMA, YOSHIKI SASAI: "Human Pluripotent Stem Cell and Neural Differentiation", BRAIN AND NERVE , vol. 60, no. 10, 31 October 2008 (2008-10-31), JP , pages 1165 - 1172, XP009536838, ISSN: 1881-6096, DOI: 10.11477/mf.1416100360
Attorney, Agent or Firm:
IPFAITH PARTNERS (CN)
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