Title:
GENERATION OF VIRUS-LIKE PARTICLES AND USE AS PANFILOVIRUS VACCINE
Document Type and Number:
WIPO Patent Application WO2006046963
Kind Code:
A9
Abstract:
In this application are described filoviruslike particles for both Ebola and Marburg and their use as a diagnostic and therapeutic agent as well as a filovirus vaccine. Also described are the association of Ebola and Marburg with lipid rafts during assembly and budding, and the requirement of functional rafts for entry of filoviruses into cells.
Inventors:
BAVARI SINA (US)
AMAN M JAVAD (US)
WARFIELD KELLY (US)
AMAN M JAVAD (US)
WARFIELD KELLY (US)
Application Number:
PCT/US2005/012378
Publication Date:
July 06, 2006
Filing Date:
April 13, 2005
Export Citation:
Assignee:
U S ARMY MEDICAL RES INST OF I (US)
BAVARI SINA (US)
AMAN M JAVAD (US)
WARFIELD KELLY (US)
BAVARI SINA (US)
AMAN M JAVAD (US)
WARFIELD KELLY (US)
International Classes:
A61K39/12; C07K14/08; C12N7/00
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